Biography
Dr. Buckles holds faculty appointments at Dillard University and Louisiana State University Health Sciences Center. He completed postdoctoral research at Virginia Commonwealth University and the University of Maryland where his research focused on understanding molecular mechanisms of bacterial pathogenesis in uropathogenic Escherichia coli. Dr. Buckles’ current research aimed at understanding the structural changes in the androgen gene and protein during the early stages of prostate cancer in African American men. Dr. Buckles has published in the Journal of Infectious Diseases, Infection and Immunity, Microbiology, and the Proceedings of the National Academy of Sciences.
Industry Expertise (4)
Environmental Services
Research
Training and Development
Education/Learning
Areas of Expertise (4)
Environmental Services
Coastal Communities
Impact of Natural Disasters
Community Gardens
Education (2)
Meharry Medical College: Ph.D., Microbiology 2001
Alcorn State University: B.Sc., Biology 1995
Affiliations (4)
- American Society of Microbiology : Member
- Dillard University : Institutional Review Board Committee
- Dillard University : Research and Sponsored Program Committee
- Dillard University : Intercollegiate Athletics Committee
Event Appearances (1)
The Role of K2 Capsule in Escherichia coli Urinary Tract Infection and Serum Resistance
48th Annual ICCACC/IDSA 46th Annual Meeting Washington, DC.
2008-10-01
Articles (5)
Development of an OspC-based tetravalent, recombinant, chimeric vaccinogen that elicits bactericidal antibody against diverse Lyme disease spirochete strains
Vaccine
2007-01-01
Lyme disease is the most common arthropod-borne disease in North America and Europe. At present, there is no commercially available vaccine for use in humans. Outer surface protein C (OspC) has antigenic and expression characteristics that make it an attractive...
Selective Binding of Borrelia burgdorferi OspE Paralogs to Factor H and Serum Proteins from Diverse Animals: Possible Expansion of the Role of OspE in Lyme Disease Pathogenesis
Infection and Immunity
2005-01-01
The binding of Borrelia burgdorferi OspE, OspF, and family 163 (Elp) proteins to factor H/factor H-like protein 1 (FHL-1) and other serum proteins from different animals was assessed. OspE paralogs bound factor H and unidentified serum proteins from a subset of animals, while OspF and Elp proteins did not...
Demonstration of OspC Type Diversity in Invasive Human Lyme Disease Isolates and Identification of Previously Uncharacterized Epitopes That Define the Specificity of the OspC Murine Antibody Response
Infection and Immunity
2005-12-01
Outer surface protein C (OspC) of the Lyme disease spirochetes is an important virulence factor that has potential utility for vaccine development. Of the 21 OspC types that have been identified, it has been postulated that types A, B, I, and K are specifically associated with invasive infections...
Transcriptome of uropathogenic Escherichia coli during urinary tract infection
Infection and Immunity
2004-01-01
A uropathogenic Escherichia coli strain CFT073-specific DNA microarray that includes each open reading frame was used to analyze the transcriptome of CFT073 bacteria isolated directly from the urine of infected CBA/J mice...
Type 1 fimbriae and extracellular polysaccharides are preeminent uropathogenic Escherichia coli virulence determinants in the murine urinary tract
Molecular Microbiology
2002-01-01
Escherichia coli is the leading cause of urinary tract infections (UTIs). Despite the association of numerous bacterial factors with uropathogenic E. coli (UPEC), few such factors have been proved to be required for UTI in animal models. Previous investigations of urovirulence factors have relied on prior identification of phenotypic characteristics. We used signature-tagged mutagenesis (STM) in an unbiased effort to identify genes that are essential for UPEC survival within the murine urinary tract...
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