Angela Fortner McKoy, Ph.D.
Adjunct Professor of Chemistry | Wheaton College
Wheaton, IL, UNITED STATES
Professor of Chemistry with expertise in X-ray crystallographic structure determination and expression and purification of polyproteins.
Biography
Dr. McKoy came to Wheaton College in 2014 as a visiting professor in Biochemistry. Her post doctoral work is in X-ray crystallographic structure determination and expression and purification of polyproteins. While at Princeton University she worked on the discovery of compounds that rescue Alzheimer's peptide toxicity through E. coli protein expression screening.
Education (4)
Princeton University: Ph.D., Biochemistry 2011
Jackson State University: M.S., Chemistry 2006
Jackson State University: B.S., Summa Cum Laude, Chemistry 2005
Center for Advanced Biotechnology and Medicine at Rutgers University: National Institutes of Health Postdoctoral Fellow 2014
National Research Service Award
Areas of Expertise and Research Interests (4)
Alzheimer's
Education
Biochemistry
Chemistry
Links (1)
Select Articles, Chapters, Reviews, and Other Publications (4)
Gold Nanoparticle Based FRET Asssay for the Detection of DNA Cleavage
Journal of Physical Chemistry
Paresh Chandra Ray, Angela Fortner, and Gopala Krishna Darbha
2006-09-03
We report gold nanoparticle based FRET assay to monitor the cleavage of DNA by nucleases. Fluorescence signal enhancement is observed by a factor of 120 after the cleavage reaction in the presence of S1 nuclease.
Gold-nanoparticle-based miniaturized laser-induced fluorescence probe for specific DNA hybridization detection: studies on size-dependent optical properties
Nanotechnology
Chan Kyu Kim, Rajamohan R Kalluru, Jagdish P Singh, Angela Fortner, Jelani Griffin, Gopala K Darbha and Paresh Chandra Ray
2006-06-05
A compact, highly specific, inexpensive and user friendly optical fibre laser-induced fluorescence (LIF) sensor based on fluorescence quenching by nanoparticles has been developed to detect single-strand (ss-) DNA hybridization at femtomolar level.
Laser-induced fluorescence quenching of tagged oligonucleotide probes by gold nanoparticles
Chemical Physics Letters
Paresh Chandra Ray, Angela Fortner, Jelani Griffin, Chan Kyu Kim, Jagdish P. Singh, Hongtao Yu
2005-08-01
Laser induced fluorescence studies of single-strand (ss) DNA hybridization based on fluorescence quenching by gold nanoparticle through a distant dependent process has been carried out. Distance- and size-dependent optical absorption properties have been described using extended Mie calculations and compared with the experimental findings.
Near infrared photo-induced DNA damage in the presence of copper-dppz complex: Evidence for the involvement of singlet oxygen
Chemical Physics Letters
Angela Fortner, Shugwang Wang, Gopala Krishna Darbha, Anandhi Ray, Hongtao Yu, Paresh Chandra Ray, Rajamohan R. Kalluru, Chan Kyu Kim, Vinita Rai, Jagdish P. Singh
2006-11-01
We present the effect of the DNA damage efficiency by excitation wavelengths above 700 nm within d–d transition bands of (l-lysine) (dppz) Cu(II) complexes.