Social

Industry Expertise (3)

Biotechnology

Research

Education/Learning

Areas of Expertise (4)

Bacterial Genetics

Infectious Disease

Microbiology

Molecular Biology

Education (2)

Randolph-Macon Woman's College: B.S., Biology and Chemistry 2003

Penn State University: Ph.D., Microbiology and Molecular Biology 2010

Affiliations (1)

• American Society for Microbiology

Courses (4)

Clinical Microbiology

The general characteristics of bacteria, protozoa, yeasts, molds and viruses are used to understand the role of microorganisms in human health and disease. The interactions between the host and the microorganisms are emphasized as well as the physical and chemical methods of control. Infectious disease agents are covered by body system. Course includes lecture and lab.

Microbiology

This course surveys microbial life including bacteria, fungi, protozoa, and viruses (with an emphasis on bacteria). Topics covered include microbial characteristics, physical and chemical control, metabolism, enzymes, regulation of enzyme activity, bacterial genetics, microbial diversity, microbial control, and applications of microbiology. The laboratory includes aseptic technique, staining procedures, culture methods, cultural and physical characteristics, microbial control, microbiology of food, water, and soil, microbiology of the body, and identification of unknowns. This course includes lecture and lab.

Microbial Pathogenesis

This course will introduce the microorganisms responsible for many common diseases and the ways in which the human body can protect itself against these disease agents. Topics include immunology, bacteriology, virology, mycology, parasitology, and microbial pathogenesis. Lectures, case studies, current events, and discussions will be integral parts of this course. The course includes lecture and lab.

Outbreak Investigations: Case Studies in Epidemiology

At times, human societies have difficulty separating fact from fallacy. This is especially true during times of stress, such as when the Spanish flu swept the globe killing millions of people in 1918-1919. Uncertainties and false conclusions regarding the identity of the specific pathogen and the mode of transfer from one individual to another led to delayed or poor decisions that resulted in significantly more deaths. Health and human services were far exceeded and measures were taken that most would find unacceptable today. HIV/AIDS is another example of where the blend of fact and fallacy has led to the death of millions. Modern epidemiology has a set of approaches designed to help separate fact from fallacy and to help the human population effectively detect, identify, monitor, contain, prevent, and possibly eradicate a new or existing disease. In this course you will learn about these epidemiologic principles and concepts (e.g., confounding, bias, causal mechanisms) all within the context of case studies associated with outbreaks of toxic shock syndrome, Legionnaires' disease, measles, mumps, syphilis, yellow fever, Ebola hemorrhagic fever, and other diseases.

Articles (7)

The EXIT Strategy: an Approach for Identifying Bacterial Proteins Exported during Host Infection.

MBio

Perkowski E.F., Zulauf K.E., Weerakoon D., Hayden J.D., Ioerger T.R., Oreper D., Gomez S.M., Sacchettini J.C., Braunstein M.

2017-04-25

The EXIT Strategy: an Approach for Identifying Bacterial Proteins Exported during Host Infection.

Inhaled Pyrazinoic Acid Esters for the Treatment of Tuberculosis

Pharm Res

Young E.F., Perkowski E., Malik S., Hayden J.D., Durham P.G., Zhong L., Welch J.T., Braunstein M.S., Hickey A.J.

2016-10-01

Inhaled Pyrazinoic Acid Esters for the Treatment of Tuberculosis

An orphaned Mce-associated membrane protein of Mycobacterium tuberculosis is a virulence factor that stabilizes Mce transporters

Mol Microbiol

Perkowski E.F., Miller B.K., McCann J.R., Sullivan J.T., Malik S., Allen I.C., Godfrey V., Hayden J.D., Braunstein M.

2015-12-29

An orphaned Mce-associated membrane protein of Mycobacterium tuberculosis is a virulence factor that stabilizes Mce transporters

Filtration improves the performance of a high-throughput screen for anti-mycobacterial compounds

PLoS One

Cheng N., Porter M.A., Frick L.W., Nguyen Y., Hayden J.D., Young E.F., Braunstein M.S., Hull-Ryde E.A., Janzen W.P.

Filtration improves the performance of a high-throughput screen for anti-mycobacterial compounds

Reversible acetylation regulates acetate and propionate metabolism in Mycobacterium smegmatis.

Microbiology

Hayden J.D., Brown L.R.*, Gunawardena H.P. Perkowski E.F., Chen X. and Braunstein M.

2013-09-01

Reversible acetylation regulates acetate and propionate metabolism in Mycobacterium smegmatis.

The ins and outs of Mycobacterium tuberculosis protein export.

Tuberculosis (Edinb)

Ligon L., Hayden J.D. and Braunstein M.

2012-03-01

The ins and outs of Mycobacterium tuberculosis protein export.

The extracytoplasmic stress factor, σE, is required to maintain cell envelope integrity in Escherichia coli.

PLoS One

Hayden J.D. and Ades S.E.

2008-02-06

The extracytoplasmic stress factor, σE, is required to maintain cell envelope integrity in Escherichia coli.