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Biography
Michael S Goligorsky, M.D., Ph.D., holds the Alvin I. Goodman Chair in Nephrology, and is Professor of Medicine, Pharmacology and Physiology, Academic Chief of Renal Division, and Director of Renal Research Institute at the New York Medical College. After completing residency and fellowship, Michael joined the faculty of the State University of New York at Stony Brook (1988). He became a Professor of Medicine and Physiology in 1997 and named an Honorary Professor at the University College London (1998). In 2002 he was recruited by the New York Medical College to inaugurate Renal Research Institute. In 1991, Michael was elected to the American Society of Clinical Investigations; in 2002 elected to the American Association of Physicians. MSG serves as an Associate Editor for Am J Pathology, Am J Physiology: Cell, and a Topic Editor for Nephrology, Dialysis and Transplantation. His research interests include: the mechanisms of endothelial dysfunction as a harbinger of atherosclerotic, diabetic, and hypertensive vascular damage; stress-induced premature senescence (SIPS) of endothelial cells and the role of lysosomal dysfunction in this process; mechanisms of functional incompetence of endothelial progenitor cells (EPC) in chronic kidney disease; mechanisms of Alarm Signaling by an ischemic organ; and proteomic analysis of the urine in kidney disease.
Industry Expertise (4)
Health Care - Services
Training and Development
Biotechnology
Research
Areas of Expertise (4)
Nephrology
Cell Biology
Immune Responses
Stem Cell Research
Education (2)
Kiev Medical Institute, Ukraine: Ph.D., Medicine
Kiev Medical Institute, Ukraine: M.D., Medicine
Affiliations (1)
- New York Medical College : Academic Chief, Renal Division
Articles (selected) (5)
Nitric oxide in acute renal failure: NOS versus NOS
Kidney International
2002-01-01
Nitric oxide in acute renal failure: NOS versus NOS. This overview provides information on the pathophysiology of the inducible nitric oxide synthase/nitric oxide (iNOS/NO) system in the injury to cultured renal tubular epithelia, freshly isolated proximal ...
Workshop: Endothelial Cell Dysfunction Leading to Diabetic Nephropathy Focus on Nitric Oxide
Hypertension
2001-01-01
Clinical manifestations of diabetic nephropathy are an expression of diabetic microangiopathy. This review revisits the previously proposed Steno hypothesis and advances our hypothesis that development of endothelial cell dysfunction represents a ...
Production and physiological actions of anandamide in the vasculature of the rat kidney
Journal of Clinical Investigation
1997-01-01
The endogenous cannabinoid receptor agonist anandamide is present in central and peripheral tissues. As the kidney contains both the amidase that degrades anandamide and transcripts for anandamide receptors, we characterized the molecular components of ...
Cannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia, and human monocytes
Journal of Biological Chemistry
1996-01-01
The present study demonstrates that stereoselective binding sites for anandamide, a naturally occurring cannabinoid substance, can be found in invertebrate immunocytes and microglia. The anandamide-binding site is monophasic and of high affinity, exhibiting a K ...
Termination of endothelin signaling: role of nitric oxide
Journal of Cellular Physiology
1994-01-01
Cellular mechanisms responsible for the termination of ET-1 signal are poorly understood. In order to examine the hypothesis that nitric oxide serves as a physiological brake of ET-1 signaling, Chinese hamster ovary (CHO) cells stably transfected with the ET ...
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