Adam Moeser
Matilda R. Wilson Endowed Chair Michigan State University
- East Lansing MI
Adam Moeser researches how early-life adversity affects the development of brain-gut axis communication and disease risk across the lifespan
Media
Biography
Industry Expertise
Areas of Expertise
Accomplishments
William J. Beal Outstanding Faculty Award
Michigan State University
Education
University of Massachusetts, Amherst
B.S.
Veterinary and Animal Sciences
North Carolina State University
M.S.
Animal Science
North Carolina State University
Ph.D.
Physiology
North Carolina State University
D.V.M.
News
Too much stress can make you physically ill. Researchers now may know why.
NBC News online
2018-01-21
It’s not a surprise when cold and flu season strike once a year with aches, pains and bodily misery. However, something even more virulent has the ability to make us ill year-round: stress.
COVID-19’s deadliness for men is revealing why researchers should have been studying immune system sex differences years ago
The Conversation online
2020-06-09
When it comes to surviving critical cases of COVID-19, it appears that men draw the short straw.
Initial reports from China revealed the early evidence of increased male mortality associated with COVID. According to the Global Health 50/50 research initiative, nearly every country is now reporting significantly higher COVID-19-related mortality rates in males than in females as of June 4.
Who’s stronger? An immunological battle of the sexes
The Conversation online
2019-02-14
Is there anything more exciting than a battle of the sexes? In popular culture, this usually focuses on societal gender roles. But, there’s another battle of the sexes, a biological war waged by the body’s immune system. Can this conflict finally tell us who is stronger – men or women?
Here’s how stress may be making you sick
MSU Today online
2018-01-10
A Michigan State University researcher is providing new insight into how certain types of stress interact with immune cells and can regulate how these cells respond to allergens, ultimately causing physical symptoms and disease.
The federally funded study, published in the Journal of Leukocyte Biology, showed how a stress receptor, known as corticotropin-releasing factor, or CRF1, can send signals to certain immune cells, called mast cells, and control how they defend the body.
Journal Articles
Sex Differences in Mast Cell–Associated Disorders: A Life Span Perspective
Cold Spring Harbor Perspectives in BiologyEmily Mackey, Adam J Moeser
2022-10-14
Mast cells are critical innate immune effectors located throughout the body that are crucial for host defense mechanisms via orchestrating immune responses to a variety of host and environmental stimuli necessary for survival. The role of mast cells in brain development and behavior, meningeal function, and stress-related disorders has also been increasingly recognized.
Neuroimmunology of depression
Advances in PharmacologyErika Sarno, Adam J. Moeser, Alfred J. Robison
2021-04-26
Depression is one of the leading causes of disability worldwide and a major contributor to the global burden of disease, yet the cellular and molecular etiology of depression remain largely unknown. Major Depressive Disorder (MDD) is associated with a variety of chronic physical inflammatory and autoimmune disorders, and mood disorders may act synergistically with other medical disorders to worsen patient outcomes.
Sleep Disorders in dogs: A Pathophysiological and Clinical Review
Topics in Companion Animal MedicineAlejandra Mondino, Luis Delucchi, Adam Moeser, Sofía Cerdá-González, Giancarlo Vanini
2021-06-01
Sleep is a fundamental process in mammals, including domestic dogs. Disturbances in sleep affect physiological functions like cognitive and physical performance, immune response, pain sensation and increase the risk of diseases. In dogs, sleep can be affected by several conditions, with narcolepsy, REM sleep behavior disorder and sleep breathing disorders being the most frequent causes.
Early weaning and biological sex shape long-term immune and metabolic responses in pigs
Scientific ReportsMahsa Fardisi, Kyan Thelen, Allegra Groenendal, Mrigendra Rajput, Kimberly Sebastian, G. Andres Contreras & Adam J. Moeser
2023-09-23
During the early pre and postnatal life, host and environmental factors can impart a major influence on immune development, thus shaping lifelong disease resistance. Two major factors known to influence immune function and mortality in animals and people are early life stress and biological sex. How these two factors interact to shape long-term immune development and later life disease risk is poorly understood.
