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Andrea Zandoná, Ph.D., D.D.S. - UNC-Chapel Hill. Chapel Hill, NC, US

Andrea Zandoná, Ph.D., D.D.S. Andrea Zandoná, Ph.D., D.D.S.

Associate Professor, Operative Dentistry | UNC-Chapel Hill


Dr Zandoná's research into the prevention and management of dental caries has led to federal and industry funding.





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Andrea F. Zandoná, D.D.S., M.S.D., Ph.D., is a tenured Associate Professor at the Department of Operative Dentistry at the University of North Carolina at Chapel Hill School of Dentistry (UNC SOD). Dr. Zandoná is originally from Curitiba, Brazil, where she received her dental degree from Pontifícia Universidade Católica do Paraná. Dr. Zandoná earned her master’s degree in dental sciences in operative dentistry and a Ph.D. in dental sciences from Indiana University.

She was a faculty member at Indiana University from 1998 until 2013, directing their graduate residency program in preventive dentistry. Her research interests in early caries detection, prevention and management of dental caries has led to federal and industry funding. She has published and lectured nationally and internationally on prevention and management of dental caries, serving on editorial boards and as reviewer for numerous scientific and dental journals. Dr. Zandoná’s clinical focus is on providing state of the art evidence-based practice of preventive and conservative management of dental caries. Her academic focus is on development of the cariology curriculum for the D.D.S. program at the UNC School of Dentistry.

Industry Expertise (3)

Medical/Dental Practice



Areas of Expertise (6)

Oral Care During Pregnancy

Clinical Education


Operative Dentistry


Diagnostic and Risk Assessment Methods

Education (3)

Pontifical Catholic University of Parana, Brazil: D.D.S., Dentistry 1990

Indiana University School of Dentistry: M.S.D., Operative Dentistry

Indiana University School of Dentistry: Ph.D., Dental Sciences

Media Appearances (1)

IU-led research will help dentists determine potential cavity sites, offer preventative treatment

Indiana University-Purdue University Indianapolis  online


The results of the study were published in the September 2012 issue of the Journal of Dental Research. The study was led by Andrea Ferreira Zandona, DDS, Ph.D, director of the Graduate Preventive Dentistry Program, director of the Department of Preventive and Community Dentistry 's Early Caries Detection and Management Program, and associate professor in the Department of Preventive and Community Dentistry, in the IU dental school...

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Articles (7)

The natural history of dental caries lesions: a 4-year observational study.

Journal of Dental Research


Dental caries is a ubiquitous disease affecting all age groups and segments of the population. It is known that not all caries lesions progress to cavitation, but little is known regarding the progression pattern of caries lesions. This study's purpose was to evaluate the natural history of dental caries using a standardized, visually based system, the International Caries Detection and Assessment System (ICDAS).

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Longitudinal analyses of early lesions by fluorescence: an observational study.

Journal of Dental Research


Previous caries experience correlates to future caries risk; thus, early identification of lesions has importance for risk assessment and management. In this study, we aimed to determine if Quantitative Light-induced Fluorescence (QLF) parameters--area (A [mm(2)]), fluorescence loss (F [%]), and Q [% × mm(2)]--obtained by image analyses can predict lesion progression.

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The impact of gender on caries prevalence and risk assessment

Dental Clinics of North America

2013 ABSTRACT: Cultural and social differences between men and women influence their oral health status by affecting their exposure to risk factors and shaping their access to protective factors and care...

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The effect of strontium and combinations of strontium and fluoride on the remineralization of artificial caries lesions in vitro

Quintessence International

2012 OBJECTIVE: To determine the effect of relatively low strontium concentrations on enamel remineralization and investigate the dose-response effects of strontium and fluoride combinations on the remineralization of artificial caries lesions in vitro...

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Dental caries and pulpal disease

Dental Clinics of North America

2011 ABSTRACT: The current practice of dentistry remains weighted towards surgically treating the consequences of dental caries. The importance of accurately diagnosing dental caries has in the past been overshadowed by the need to restore the extensive damage to tooth structure...

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Diagnostic tools for early caries detection

The Journal of the American Dental Association

2006 ABSTRACT: Management of dental caries demands early detection of carious lesions. This article provides an overview of the state-of-the-art methodologies for the detection of...

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Rationale and protocol for the treatment of non-cavitated smooth surface carious lesions

General Dentistry

2006 ABSTRACT: The decision to restore a smooth surface carious lesion should be based on whether the lesion has cavitated. All non-cavitated lesions should...

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