Anna-Lisa Paul

Director | Professor University of Florida

  • Gainesville FL

Anna-Lisa Paul’s research focuses on molecular genetic responses of plants to spaceflight and planetary exploration-relevant environments.

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University of Florida

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Biography

Anna-Lisa Paul is the Director of the Interdisciplinary Center for Biotechnology Research and a research Professor of Horticultural Sciences in the program of Plant Molecular and Cellular Biology. She is part of the UF-Research senior executive group and is chair of the Astraeus Space Institute Administrators council. Anna Lisa’s research focuses on plant gene expression in response to environmental change relevant to space exploration. Anna-Lisa uses orbital and suborbital environments to study the molecular genetic/epigenetic responses of plants to spaceflight and the transition to space, worked in extreme terrestrial environments, and worked with true lunar regolith from the Apollo era. Paul serves on two National Academies Committees associated with space exploration research.

Areas of Expertise

Astrobotany
Moon habitats
Luna regolith
Exploration science
Space molecular genetics
Space plant biology
Space transcriptome
Planetary analogs
Mars habitats
Planetary greenhouse

Media Appearances

Seeding Exploration

Florida Trend  online

2025-05-07

UF scientists Rob Ferl and Anna-Lisa Paul preach teamwork. That approach helped them take a giant leap for interplanetary exploration.

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Humans are explorers — go boldly

TED  online

2019-04-01

Humans are explorers, and space is what is next. Plants allows us to explore past the limits of a picnic basket to destinations beyond Earth’s orbit. In this talk, Research Professor Dr. Anna-Lisa Paul plants the seeds to a future of agriculture in space.

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Space Plants

Shorthand Social  online

2017-03-03

Anna-Lisa Paul's hands are steady. The pressure to plant 20 to 30 seeds in a tiny petri dish using a water dropper in under 10 minutes doesn’t faze her. Granted, the University of Florida plant molecular biologist has been doing this for "20 odd years."

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Articles

Light has a principal role in the Arabidopsis transcriptomic response to the spaceflight environment

Nature

Zhou, et al.

2024-08-06

The Characterizing Arabidopsis Root Attractions (CARA) spaceflight experiment provides comparative transcriptome analyses of plants grown in both light and dark conditions within the same spaceflight. CARA compared three genotypes of Arabidopsis grown in ambient light and in the dark on board the International Space Station (ISS); Col-0, Ws, and phyD, a phytochrome D mutant in the Col-0 background.

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Transcriptomic dynamics in the transition from ground to space are revealed by Virgin Galactic human-tended suborbital spaceflight

Nature

Ferl, et al.

2023-12-20

The Virgin Galactic Unity 22 mission conducted the first astronaut-manipulated suborbital spaceflight experiment. The experiment examined the operationalization of Kennedy Space Center Fixation Tubes (KFTs) as a generalizable approach to preserving biology at various phases of suborbital flight.

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Plants grown in Apollo lunar regolith present stress-associated transcriptomes that inform prospects for lunar exploration

Nature

Paul, et al.

2022-05-12

The extent to which plants can enhance human life support on other worlds depends on the ability of plants to thrive in extraterrestrial environments using in-situ resources. Using samples from Apollo 11, 12, and 17, we show that the terrestrial plant Arabidopsis thaliana germinates and grows in diverse lunar regoliths. However, our results show that growth is challenging; the lunar regolith plants were slow to develop and many showed severe stress morphologies.

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Media