Aria Eshraghi

Assistant Professor University of Florida

Gainesville FL

Aria Eshraghi has expertise in infection microbiology and his team's goal is to develop new ways to prevent and treat infections.

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Biography

Aria Eshraghi's research program investigates how bacteria use virulence factors to evade detection by the immune system and cause disease. Aria's team uses highly pathogenic bacteria as models to understand how bacteria inject toxins into the host and to characterize the pathways that underlie pathogenesis. Aria's goal is to discover these bacterial pathways and toxins so that we can develop countermeasures to prevent and treat infections.

Areas of Expertise

Francisella

Francisellosis

Graduate Education in the Life Sciences

Tularemia

Tularensis

Media Appearances

How Yersinia bacterium evade the immune system: University of Florida research

Outbreak News Today online

2021-07-29

New research from the University of Florida explains how a family of bacteria called Yersinia infects the body so successfully. Yersinia bacteria, a family that includes the bacterium responsible for bubonic plague, is able go undetected by interrupting communication between immune system cells and the site of the infection, the researchers showed.

Social

Articles

A phosphatidylinositol 3-kinase effector alters phagosomal maturation to promote intracellular growth of francisella.

Cell Host & Microbe

Hannah E Ledvina, et. al

2018-07-26

Many pathogenic intracellular bacteria manipulate the host phago-endosomal system to establish and maintain a permissive niche. The fate and identity of these intracellular compartments is controlled by phosphoinositide lipids. By mechanisms that have remained undefined, a Francisella pathogenicity island-encoded secretion system allows phagosomal escape and replication of bacteria within host cell cytoplasm.