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Jennifer Dungan - University of Florida. Gainesville, FL, US

Jennifer Dungan Jennifer Dungan

Associate Professor | University of Florida

Gainesville, FL, UNITED STATES

Jennifer Dungan’s primary area of scientific expertise is in the use of genetic epidemiology.

Biography

Jennifer Dungan’s primary area of scientific expertise is in the use of genetic epidemiology to study complex cardiovascular diseases and outcomes. Dungan is also interested in collaborating on projects related to women’s heart disease, functional genetic studies of coronary disease candidate genes, as well as clinical and genetic biorepositories.

Industry Expertise (2)

Education/Learning

Health and Wellness

Areas of Expertise (3)

Women’s Heart Disease

Cardiovascular Disease

Genetics

Media Appearances (1)

Nursing Now

Explore Research at the University of Florida  online

2020-04-24

As a doctoral student at the UF College of Nursing in the early 2000s, Jennifer Dungan regularly biked to the UF Health Shands Hospital carrying a biohazard cooler to collect and study human coronary artery fragments removed during heart bypass surgeries. Dungan used the tissue in her doctoral research to determine whether certain genes were expressed differently among people without high blood pressure.

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Articles (5)

Genome-Wide Variants Associated With Longitudinal Survival Outcomes Among Individuals With Coronary Artery Disease

Frontiers in Genetics

Coronary artery disease (CAD) is an age-associated condition that greatly increases the risk of mortality. The purpose of this study was to identify gene variants associated with all-cause mortality among individuals with clinically phenotyped CAD using a genome-wide screening approach.

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Protein Cytokines, Cytokine Gene Polymorphisms, and Potential Acute Coronary Syndrome Symptoms

Biological Research For Nursing

The purpose of this study was to determine whether relationships exist among protein cytokines, cytokine gene polymorphisms, and symptoms of potential acute coronary syndrome (ACS). Participants included 438 patients presenting to the emergency department (ED) whose symptoms triggered a cardiac evaluation (206 ruled in and 232 ruled out for ACS). Presence or absence of 13 symptoms was recorded upon arrival. Levels of tumor necrosis factor α (TNF-α), interleukin (IL)-6, and IL-18 were measured for all patients.

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Polygenic signal for symptom dimensions and cognitive performance in patients with chronic schizophrenia

Schizophrenia Research: Cognition

Genetic etiology of psychopathology symptoms and cognitive performance in schizophrenia is supported by candidate gene and polygenic risk score (PRS) association studies. Such associations are reported to be dependent on several factors - sample characteristics, illness phase, illness severity etc. We aimed to examine if schizophrenia PRS predicted psychopathology symptoms and cognitive performance in patients with chronic schizophrenia.

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Biases in Genetic Association of Coronary Heart Disease Events May Be Less Likely Than Suspected

Circulation: Cardiovascular Genetics

Investigating lethal diseases like coronary heart disease (CHD) and major adverse events like myocardial infarction (MI) and death can sometimes seem a bit macabre. We are interested in understanding the events with the hope of preventing them; yet, to demonstrate effects, it is essential for a high rate of such unfortunate events to occur and to be observed. Fortunately, the increasing availability of big [event] data supports an unprecedented ability and power to explore genetic influences on primary and subsequent CHD events. Tempering the enthusiasm around this opportunity is the concern for biases that threaten the internal and external validity of such investigations.

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Genetic correlates of insight in schizophrenia

Schizophrenia Research

Insight in schizophrenia is clinically important as it is associated with several adverse outcomes. Genetic contributions to insight are unknown. We examined genetic contributions to insight by investigating if polygenic risk scores (PRS) and candidate regions were associated with insight.

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Languages (1)

  • English

Affiliations (6)

  • Biological Research For Nursing : Editorial Board Member
  • International Society of Nurses in Genetics : Member
  • NIH Genome Blueprint Working Group : Member
  • Omics Nursing Science and Education Network (ONSEN) : Member
  • American Heart Association : Member
  • American Society of Human Genetics : Member