Miriam Ezenwa’s research explores health disparities in pain management, pain and symptom management for people with sickle cell disease, as well as stress reduction interventions for sickle cell disease. Her biobehavioral research also investigates the hormone cortisol as a biomarker of stress and how computer technologies may be used to measure both stress and pain.
Industry Expertise (2)
Health and Wellness
Areas of Expertise (3)
Sickle Cell Disease
Media Appearances (4)
$7.1M NIH Grant Supports Study of Opioid Alternatives to Manage SCD Pain
Sickle Cell Disease News online
The acupuncture regime was determined by Schlaeger, who also is a licensed acupuncturist, while the relaxation techniques were developed by Miriam Ezenwa, PhD, an associate professor at University of Florida College of Nursing, who also is part of the awarded team.
$7.1M grant to review opioid alternatives to treating sickle cell disease pain
For the study, 360 SCD patients will receive acupuncture twice a week for five weeks. Judy Schlaeger, associate professor in the UIC Department of Human Development Nursing Science, who developed an SCD treatment plan, determined that the time frame allows for a successful impact on pain. Also, patients will be asked to use guided relaxation techniques at least once a day. These techniques, which patients access via smartphone or computer, were developed by Miriam Ezenwa, a University of Florida associate professor in biobehavioral nursing science. Both acupuncture and guided medication were proven effective in pilot studies on SCD pain management.
UF nursing researcher receives $2.6 million grant to improve pain associated with sickle cell disease
University of Florida Health online
Miriam O. Ezenwa, Ph.D., M.S.N., R.N., FAAN, an associate professor at the College of Nursing, is the principal investigator on the project, which aims to use self-management interventions like guided relaxation therapy to improve the lives of those with the disease.
Making an Impact: Faculty
The Gator Nurse online
Ezenwa, Ph.D., R.N., grew up with her mom, dad and nine brothers and sisters in a poor and unsafe neighborhood in Nigeria. Ezenwa remembers her neighbor receiving monthly blood transfusions to reduce his risk of a stroke but he still suffered from something called sickle cell crisis, or severe attacks of pain. During these attacks, Ezenwa didn’t see her neighbor for weeks.
Critical Role of Hemopexin Mediated Cytoprotection in the Pathophysiology of Sickle Cell DiseaseInternational Journal of Molecular Sciences
Circulating hemopexin is the primary protein responsible for the clearance of heme; therefore, it is a systemic combatant against deleterious inflammation and oxidative stress induced by the presence of free heme. This role of hemopexin is critical in hemolytic pathophysiology. In this review, we outline the current research regarding how the dynamic activity of hemopexin is implicated in sickle cell disease, which is characterized by a pathological aggregation of red blood cells and excessive hemolysis.
Pain, symptom distress, and pain barriers by age among patients with cancer receiving hospice care: Comparison of baseline dataJournal of Geriatric Oncology
Age group differences have been reported for pain and symptom presentations in outpatient and inpatient oncology settings, but it is unknown if these differences occur in hospice. We examined whether there were differences in pain, symptom distress, pain barriers, and comorbidities among three age groups (20–64 years, 65–84 years, and 85+) of hospice patients with cancer.
Development of an Online Reproductive Health Intervention for Individuals with Sickle Cell Disease or TraitWomen's Health Reports
The purpose of this article is to describe the method of developing an internet-based reproductive options intervention to increase informed reproductive decision-making among individuals with sickle cell disease (SCD) or sickle cell trait (SCT). An interprofessional team of graphics and media specialist, nurses, physicians, and researchers collaborated to develop the intervention. Individuals from the community served as advisory board members who reviewed and advised on webpage design, content, delivery, and media.
The Crisis of Sickle Cell Disease in Africa from Insights into Primary Prevention in Ghana and Nigeria: Notes from the FieldJournal of Immigrant and Minority Health
Sickle cell disease (SCD), an inherited blood disorder, impacts 2% of newborns in Nigeria and Ghana. Despite devastating health consequences, SCD prevention is not a priority in either country. This article describes our U.S. research team’s feasibility assessment for adapting CHOICES, a computer-based SCD education program, for use in Ghana and Nigeria. We identified indigenous collaborators by reviewing published research and investigating advocacy organizations online.
Clinical efficacy and implementation issues of an electronic pain reporting device among outpatients with cancerSupportive Care in Cancer
Collecting patients’ pain features for congruent pain relief treatment is time-consuming. We sought to identify implementation issues and evaluate the efficacy of an electronic patient self-reporting pain device in community-based cancer clinics.
- Midwest Nursing Research Society : Grant Review Committee Member
- American Pain Society : Member
- Midwest Nursing Research Society : Member
- Council for the Advancement of Nursing Science : Member
- Sigma Theta Tau International Nursing Honor Society : Member
- Golden Key International Honor Society : Member