Brittany L. Taylor is an assistant professor in the J. Crayton Pruitt Family Department of Biomedical Engineering in the Herbert Wertheim College of Engineering. Her research group investigates the regenerative and reparative processes of musculoskeletal tissues to inform the development of tailored acellular regenerative engineering approaches. Her group is particularly interested in identifying the biological and structural mechanisms that contribute to the limited healing capacity of tendons and using biomimetic matrices, tunable multifactorial delivery systems and modified subcellular components to overcome deficiencies and complement the healing response. Brittany also has a continuing interest in promoting diversity, equity and inclusion in STEM. She is the co-founder of multiple recruiting and mentoring initiatives for minoritized scholars.
Areas of Expertise (8)
Diversity in STEM
Rotator Cuff Tendon Injury and Repair
Tendon Biology and Biomechanics
The art of virtual mentoring in the twenty-first century for STEM majors and beyondNature Biotechnology
Melanie R. McReynolds, et al.
Social distancing restrictions have severely impacted the laboratory environment by limiting in-person activities. As a result of reduced in-person interactions between trainees, mentors and staff, the dynamic of traditional mentor–mentee relationships has also become remodeled (Fig. 1), leading many to rely on mentorship undertaken through virtual platforms. For the majority of trainees and mentors, mentorship that relies primarily on virtual platforms is an unfamiliar concept.
Localized delivery of ibuprofen via a bilayer delivery system (BiLDS) for supraspinatus tendon healing in a rat modelJournal of Orthopaedic Research
Brittany L. Taylor, et al.
The high prevalence of tendon retear following rotator cuff repair motivates the development of new therapeutics to promote improved tendon healing. Controlled delivery of non-steroidal anti-inflammatory drugs to the repair site via an implanted scaffold is a promising option for modulating inflammation in the healing environment. Furthermore, biodegradable nanofibrous delivery systems offer an optimized architecture and surface area for cellular attachment, proliferation, and infiltration while releasing soluble factors to promote tendon regeneration.
Three-Dimensional Porous Trabecular Scaffold Exhibits Osteoconductive Behaviors In VitroRegenerative and Translational Medicine
Brittany L. Taylor, et al.
In the USA, approximately 500,000 bone grafting procedures are performed annually to treat injured or diseased bone. Autografts and allografts are the most common treatment options but can lead to adverse outcomes such as donor site morbidity and mechanical failure within 10 years. Due to this, tissue engineered replacements have emerged as a promising alternative to the biological options. In this study, we characterize an electrospun porous composite scaffold as a potential bone substitute.