Biography
Carlos Rinaldi-Ramos is an international leader in the hydrodynamics and biomedical applications of magnetic nanoparticles, with emphasis on flow of magnetic nanoparticle suspensions, diffusion of nanoparticles in complex and biological fluids, and biomedical applications such as magnetic hyperthermia and magnetic particle imaging.
Areas of Expertise (10)
Nanomagnetism
Hyperthermia
Nanoparticle Diffusion
Ferrofluids
Magnetic Nanoparticles
Nanomedicine
Magnetic Particle Imaging
Ferrohydrodynamics
Nanoparticle Synthesis
Drug Delivery
Articles (3)
Fast nanoparticle rotational and translational diffusion in synovial fluid and hyaluronic acid solutions
Science AdvancesMythreyi Unni, et. al
2021-06-30
Nanoparticles are under investigation as diagnostic and therapeutic agents for joint diseases, such as osteoarthritis. However, there is incomplete understanding of nanoparticle diffusion in synovial fluid, the fluid inside the joint, which consists of a mixture of the polyelectrolyte hyaluronic acid, proteins, and other components.
Tracking adoptive T cell immunotherapy using magnetic particle imaging
NanotheranosticsAngelie Rivera-Rodriguez, et. al
2021-04-27
Adoptive cellular therapy (ACT) is a potent strategy to boost the immune response against cancer. ACT is effective against blood cancers but faces challenges in treating solid tumors. A critical step for the success of ACT immunotherapy is to achieve efficient trafficking and persistence of T cells to solid tumors. Non-invasive tracking of the accumulation of adoptively transferred T cells to tumors would greatly accelerate development of more effective ACT strategies.
Perfusion, cryopreservation, and nanowarming of whole hearts using colloidally stable cryopreservation agent solutions
Science AdvancesAndreina Chiu Lam, et. al
2021-01-08
Nanowarming of cryopreserved organs perfused with magnetic cryopreservation agents (mCPAs) could increase donor organ utilization by extending preservation time and avoiding damage caused by slow and nonuniform rewarming. Here, we report formulation of an mCPA containing superparamagnetic iron oxide nanoparticles (SPIONs) that are stable against aggregation in the cryopreservation agent VS55 before and after vitrification and nanowarming and that achieve high-temperature rise rates of up to...
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