
Christine Schmidt
Distinguished Professor University of Florida
- Gainesville FL
Christine Schmidt has spent over 25 years in neural tissue engineering & wound healing, with emphasis on peripheral nerve and spinal cord.
Biography
Areas of Expertise
Social
Articles
Injectable Neural Hydrogel as in vivo Therapeutic Delivery Vehicle
Regenerative Engineering and Translational MedicineNora Hlavac, et. al
2023-01-26
This study demonstrated the in vivo delivery of a decellularized, injectable peripheral nerve (iPN) hydrogel and explored options for using iPN in combination with regenerative biomolecular therapies like stem cell secretome. Rat-derived iPN hydrogel solutions were combined with a dextran-conjugated dye before subcutaneous injection into adult Sprague–Dawley rats. After injection, an in vivo imaging system (IVIS) was used to visualize hydrogels and quantify dextran-dye release over time.
Decellularized peripheral nerve as an injectable delivery vehicle for neural applications
Journal of Biomedical Materials Research Part ADeanna Bousalis, et. al
2022-03-01
Damage to the nervous system can result in loss of sensory and motor function, paralysis, or even death. To facilitate neural regeneration and functional recovery, researchers have employed biomaterials strategies to address both peripheral and central nervous system injuries.
Development of a magnetically aligned regenerative tissue-engineered electronic nerve interface for peripheral nerve applications
BiomaterialsMary Kasper
2021-12-01
Peripheral nerve injuries can be debilitating to motor and sensory function, with severe cases often resulting in complete limb amputation. Over the past two decades, prosthetic limb technology has rapidly advanced to provide users with crude motor control of up to 20° of freedom; however, the nerve-interfacing technology required to provide high movement selectivity has not progressed at the same rate.