Biography
Christine Schmidt is a distinguished professor who has over 25 years of experience in neural tissue engineering and wound healing, with over $25M in funding and 185 peer-reviewed papers and chapters (H-index=66) and 30 issued U.S. patents. Christine is also active in innovation, commercialization, and clinical translation efforts. Her work is the foundation for the Avance Nerve Repair graft from Axogen and the VersaWrap from Alafair Biosciences.
Areas of Expertise (6)
Spinal Cord Injury
Nerve Repair
Tissue Engineering
Biomaterials
Natural Biomaterials
Neural Tissue Engineering
Articles (3)
Injectable Neural Hydrogel as in vivo Therapeutic Delivery Vehicle
Regenerative Engineering and Translational MedicineNora Hlavac, et. al
2023-01-26
This study demonstrated the in vivo delivery of a decellularized, injectable peripheral nerve (iPN) hydrogel and explored options for using iPN in combination with regenerative biomolecular therapies like stem cell secretome. Rat-derived iPN hydrogel solutions were combined with a dextran-conjugated dye before subcutaneous injection into adult Sprague–Dawley rats. After injection, an in vivo imaging system (IVIS) was used to visualize hydrogels and quantify dextran-dye release over time.
Decellularized peripheral nerve as an injectable delivery vehicle for neural applications
Journal of Biomedical Materials Research Part ADeanna Bousalis, et. al
2022-03-01
Damage to the nervous system can result in loss of sensory and motor function, paralysis, or even death. To facilitate neural regeneration and functional recovery, researchers have employed biomaterials strategies to address both peripheral and central nervous system injuries.
Development of a magnetically aligned regenerative tissue-engineered electronic nerve interface for peripheral nerve applications
BiomaterialsMary Kasper
2021-12-01
Peripheral nerve injuries can be debilitating to motor and sensory function, with severe cases often resulting in complete limb amputation. Over the past two decades, prosthetic limb technology has rapidly advanced to provide users with crude motor control of up to 20° of freedom; however, the nerve-interfacing technology required to provide high movement selectivity has not progressed at the same rate.
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