Claire Cupples
Dean of Science and Professor of Molecular Biology & Biochemistry, Faculty of Science Simon Fraser University
- Burnaby BC
Dr. Cupples has worked as a scientist, faculty member and administrator in three Canadian comprehensive universities since 1989.
Media
Biography
Her research focuses on the causes, consequences and prevention of mutations in microbes and in humans, and she teaches in the areas of molecular biology and microbiology.
In her role as Dean, Dr. Cupples works with departments to set the strategic direction of the Faculty, oversees the budget and represents the Faculty of Science as a member of the senior administration of SFU. She has a particular interest in bringing science to school age children and the general public.
She has served on the boards of BCNet and the Science Fair Foundation of BC, and as President of the Canadian Council of Deans of Science; she is currently on the boards of TRIUMF, Bamfield Marine Sciences Centre and Science World.
Industry Expertise
Areas of Expertise
Education
York University
Ph.D.
Biology
University of Calgary
M.Sc.
Biology
University of Victoria
B.Sc.
Biology
UCLA
post-doctoral fellow
molecular genetics
Links
Media Appearances
SFU student says thanks to high school math teacher
Simon Fraser University News online
2016-05-04
Have you ever wanted to let one of your high school teachers know how much they shaped your educational experience?
SFU statistics student Nikola Surjanovic did.
Opinion: How basic academic research leads to innovation
Vancouver Sun online
2016-04-10
There’s a disconnect between Canada’s capacity to innovate and our capacity to commercialize those innovations — or so the story goes.
It’s been repeated so often it’s become a mantra in certain circles, and it was hauled out again recently in an opinion piece that wondered how we can get Canada’s health research “out of the lab and into the market.” Their solutions are always the same: reject investments in purely academic research in favour of market-driven research.
People-centered science will attract more women to the field
Vancouver Sun print
2011-03-15
You don't have to lock yourself away in a laboratory to be a successful scientist.
Opening of SFU Observatory
Global News tv
Celebrating the Trottier Observatory - a new venue for science outreach at SFU.
Call for better science education
CBC Radio radio
2012-02-20
We need to find better ways of teaching science if we are to capture students' interest.
Articles
MutL: conducting the cell's response to mismatched and misaligned DNA
Bioessays2010
Base pair mismatches in DNA arise from errors in DNA replication, recombination, and biochemical modification of bases. Mismatches are inherently transient. They are resolved passively by DNA replication, or actively by enzymatic removal and resynthesis ...
Wot the 'L—Does MutL do?
Mutation Research / Reviews in Mutation Research2010
In model DNA, A pairs with T, and C with G. However, in vivo, the complementarity of the DNA strands may be disrupted by errors in DNA replication, biochemical modification of bases and recombination. In prokaryotic organisms, mispaired bases are recognized by ...
Interaction between the mismatch repair and nucleotide excision repair pathways in the prevention of 5-azacytidine-induced CG-to-GC mutations in Escherichia coli
DNA Repair2009
5-Azacytidine induces CG-to-GC transversion mutations in Escherichia coli. The results presented in this paper provide evidence that repair of the drug-induced lesions that produce these mutations involves components of both the mismatch repair and nucleotide ...
Characterization of mutant MUTYH proteins associated with familial colorectal cancer
Gasteroenterology2008
The human mutyh gene encodes a base excision repair protein that prevents G: C to T: A transversions in DNA. Biallelic mutations in this gene are associated with recessively inherited familial colorectal cancer. The aim of this study was to ...
MBD4-mediated glycosylase activity on a chromatin template is enhanced by acetylation
Molecular and Cellular Biology2008
The ability of the MBD4 glycosylase to excise a mismatched base from DNA has been assessed in vitro using DNA substrates with different extents of cytosine methylation, in the presence or absence of reconstituted nucleosomes. Despite the enhanced ability of ...
