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Dr. Andres Lozano - University Health Network. Toronto, ON, CA

Dr. Andres Lozano Dr. Andres Lozano

Neurosurgeon, Krembil Neuroscience Centre | University Health Network

Toronto, ON, CANADA

Canada Research Chair in Neuroscience, Tier 1



Dr. Andres Lozano Publication Dr. Andres Lozano Publication Dr. Andres Lozano Publication



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Andres Lozano: Parkinson's, depression and the switch that might turn them off Pacemakers, Defibrillators and Sound: Andres Lozano at TEDxUofT Deep Brain Stimulation - Dr. Andres Lozano, October 2006 The Brain Campaign: Deep Brain Stimulation The Brain Campaign: Overview




A graduate of the University of Ottawa, Faculty of Medicine in 1983, Dr. Lozano underwent Neurosurgical Training at McGill University. He became a Fellow of the Royal College of Physicians and Surgeons of Canada in 1990. During his residency in Montreal, Dr. Lozano earned his Ph.D. in Experimental Medicine in 1989. Dr. Lozano joined the Neurosurgical Staff at the Toronto Western Hospital in 1991. He is currently Professor in the Department of Surgery, and inaugural Chair Holder of the Ron Tasker Chair in Stereotactic and Functional Neurosurgery at the University Health Network. He also holds a Tier I Canada Research Chair in Neuroscience. His main research and clinical interests lie in the field of the neurosurgical treatment of movement disorders and micro-electrode recordings of the human brain.

Industry Expertise (6)

Advanced Medical Equipment



Health Care - Services

Health Care - Providers

Health and Wellness

Areas of Expertise (10)



Alzheimer’s Disease

Deep Brain Stimulation

Functional Neurosurgery




Parkinson's Disease

Movement Disorders

Accomplishments (5)

Royal Society of Canada (professional)


Elected to membership as a leader in his field

Order of Spain (professional)


One of Spain's highest honours

H. Richard Winn Prize from the Society of Neurological Surgeons (professional)


The purpose of this international award is to encourage research in the neurosciences and to recognize outstanding, continuous commitment to research in the neurosciences by a neurological surgeon. This prize both recognizes the accomplishments of Dr. Winn, and seeks to reward a neurological surgeon who has made, and continues to make, substantial contributions to clinical or basic neuroscience.

Margolese National Brain Disorders Prize (professional)


The Margolese National Brain Disorders Prize will be awarded annually to a Canadian citizen who has made outstanding contributions to the treatment, amelioration, or cure of brain disorders.

University Professor, University of Toronto (professional)


The University of Toronto has named Dr. Andres Lozano a University Professor, the institution’s highest honour for academic excellence. The promotion recognizes Dr. Lozano’s contributions to neurosurgery research and treatments for brain disorders, as well as his commitment to education.

Only about two per cent of tenured U of T faculty members become University Professors, and Dr. Lozano is the first neurosurgeon to receive the distinction.

Education (2)

McGill University: Ph.D., Neurobiology 1990

University of Ottawa, Faculty of Medicine: MD, Medicine 1983

Affiliations (7)

  • University Professor Department of Neurosurgery University of Toronto
  • R.R. Tasker Chair in Stereotactic and Functional Neurosurgery UHN
  • Dan Family Chair in Neurosurgery
  • Chairman Department of Neurosurgery University of Toronto
  • Past-President World Society for Stereotactic and Functional Neurosurgery
  • Canada Research Chair in Neuroscience Tier 1
  • Senior Scientist Krembil Research Institute

Media Appearances (22)

Mayfield Lecturer Dr. Andres Lozano looks to DBS for new solutions to depression, Alzheimer's and epilepsy

The Mayfield Brain & Spinal Column  online


Andres Lozano, MD, PhD, Professor and Chairman of Neurosurgery at the University of Toronto and the 2014 Mayfield Lecturer, inspired an audience of faculty and neurosurgery residents Friday by illuminating the promise of deep brain stimulation (DBS) surgery for a wide range of conditions, including epilepsy and disorders related to movement, mood and memory...

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Deep brain stimulation: how far can it go?

Edge Magazine  online


In 2003, neurosurgeon Dr. Andres Lozano was performing an experimental procedure designed to suppress the appetite of a 53-year-old, 420-pound man with a lifelong history of obesity. When Lozano switched on electrodes surgically implanted in the hypothalamus, a brain area that controls hunger, the patient suddenly remembered a visit to a park with his girlfriend 30 years earlier...

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Can Hacking The Brain Make You Healthier?

NPR  online


Neurosurgeon Andres Lozano remembers the most satisfying case of his career – helping a boy with dystonia that had twisted his body to the point where he could only crawl on his stomach. The boy didn't respond to drugs, but he did respond to deep brain stimulation. Three months after surgery, he was walking like a normal child...

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Non-invasive brain surgery: an interview with Dr. Andres Lozano, University of Toronto

News Medical  online


Q. What is MR-guided focused ultrasound and what has it traditionally been used for? A. It is a new technique that involves focusing 1024 beams of ultrasound through the skull to a focal point in the brain, very much like using the sun and a magnifying glass to burn a hole in a sheet of paper...

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A surgical solution for anorexia

Globe and Mail  online


Experts at Toronto Western Hospital are in the midst of a trial application of deep brain stimulation, a surgical implantation of an electrical probe in the brain, for treatment of extreme anorexia. Health editor Paul Taylor joins Hannah Sung with footage of a patient undergoing treatment

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'Brain pacemaker' offers hope for treating severe anorexia nervosa

CTV News  tv


For patients with severe anorexia, there is often little doctors can do as they watch their patients slowly starve themselves to death. But Canadian scientists are working on what could be a new way to treat these patients using deep brain stimulation by implanting a device similar to a pacemaker.

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Brain 'pacemakers' promising for anorexia treatment

CBC News  tv


Surgically implanting pacemaker-like devices into the brains of people with severe anorexia might help improve their symptoms, a small Canadian study suggests.

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Small trial shows "brain pacemaker" may ease severe anorexia

Reuters  online


Scientists have for the first time reported successful use of a brain-stimulating implant to help patients with severe anorexia whose condition had not improved with other treatments.

Doctors implanted a device similar to a pacemaker in the brains of six severe anorexics and found at least half put on weight and showed improvements in mood. Under previous therapies, none had shown progress.

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Toronto treatment offers hope to late-stage chronic anorexics

Toronto Star  online


Electrodes permanently implanted deep in the brain can help untangle the web of mental illness that often lies behind chronic anorexia nervosa.

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Deep brain stimulation 'helps in severe anorexia nervosa'

BBC News  online


Scientists have raised the prospect that deep brain stimulation could help people suffering from severe anorexia nervosa.

In the small Canadian study three people were able to gain weight and had improvements in their overall mood after undergoing the procedure.

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Untangling Alzheimer’s

CBC The Nature of Things  tv


Untangling Alzheimer's is a dramatic and inspiring medical investigation driven by David Suzuki's journey to understand the science of Alzheimer's and the surprising new insights into its cause.

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Brain Implants Hold Promise Restoring Combat Memory Loss

Bloomberg  online


The Pentagon is exploring the development of implantable probes that may one day help reverse some memory loss caused by brain injury.

The goal of the project, still in early stages, is to treat some of the more than 280,000 troops who have suffered brain injuries since 2000, including in combat in Iraq and Afghanistan.

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Unravelling Dementia: Why researchers still can't tell us what causes or cures Alzheimer's

CBC The Current  radio


Each week there's a new study about Alzheimer's disease in the news...but what do we really know about dementia? We'll hear about the latest research in prevention and treatment, and find out how close we are to finding answers.

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Brain implant could restore MEMORIES in wounded soldiers and Alzheimer's sufferers - but is it ethical?

Daily Mail UK  online


Aside from the physical impacts brain damage has on the body, the loss of memory can be as devastating and restrictive.
The U.S. Defense Advanced Research Projects Agency is working on restoring these memories using brain implants that could reverse the loss in wounded soldiers, and benefit Alzheimer's and dementia patients.

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The self-starving brain

Aeon Magazine  online


Anorexia remains a deadly and mysterious illness. Could radical new brain treatments offer the possibility of a cure?

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Former Metro Morning host Andy Barrie battles Parkinson’s with brain surgery

Toronto Star  online


Parkinson’s left him “like a marionette with the strings cut. You just slump there.” But deep brain stimulation dialed back the clock on his disease.

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Deep Brain Stimulation Shows Promise for Patients with Alzheimer’s

University Health Network  online


In a world first, Dr. Andres M. Lozano and his team at Toronto Western Hospital has shown using Deep Brain Stimulation (DBS) on patients with early signs of Alzheimer's disease is safe and may help improve memory.

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Groundbreaking Treatment: Scalpel-Free Surgery Proving Successful

University Health Network  online


In a Canadian first, Dr. Andres Lozano, a neurosurgeon at the Krembil Neuroscience Centre and a team of co-investigators at Sunnybrook Health Sciences Centre, have pioneered a procedure using MRI-guided focused ultrasound to successfully treat patients with disabling tremors.

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Andres Lozano First Neurosurgeon Appointed as U of T University Professor

University Health Network  online


Dr. Andres Lozano has been appointed as a 2014 University Professor at the University of Toronto. He is the first neurosurgeon to receive this prestigious appointment, which recognizes U of T's most outstanding scholars.

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Brain Surgery Gives 'New Life, New Hope' to Anorexia Patient

University Health Network  online


In 2011, after being unable to complete yet another treatment program, Kim heard about a study involving anorexia patients. It was unlike any treatment she'd ever heard of before. It involved brain surgery – and she signed up immediately.

The study, led by Dr. Andres Lozano at UHN's Krembil Neuroscience Centre at Toronto Western Hospital, involved a procedure called Deep Brain Stimulation (DBS).

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Toronto Western Hospital Implants First Patient for North American Feasibility Study Using ‘Brain Pacemaker’ for Alzheimer’s: Study Builds on Earlier Research Pioneered at Toronto Western

University Health Network  online


The first patient in The ADvance Study, a clinical trial being conducted in the U.S. and Canada to assess deep brain stimulation (DBS) in patients with mild Alzheimer's disease has successfully been implanted at the Krembil Neuroscience Centre, Toronto Western Hospital (TWH). The study is sponsored by Functional Neuromodulation.

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Celebrating the Deep Brain Stimulation Journey

University Health Network  online


On September 10th the Movement Disorders Clinic held a celebration to recognize some their first DBS patients, all of whom have helped advance the treatment and enabled doctors, scientists and surgeons at the Krembil Neuroscience Centre to become world leaders for DBS.

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Event Appearances (3)

Society for Neurosurgery - Cell translation course

Translational Neuroscience: Bridging the Gap Between Basic Research Discoveries and Clinical Applications  Arlington, VA.


The Brain on Circuit Training: Finding and Fixing Misfiring Neural Circuitry

Neurofutures 2014  Seattle, WA.


Adjusting Dials on Circuits in the Human Brain

TEDxCaltech  California Institute of Technology, CA.


Articles (5)

Parkinson's disease New England Journal of Medicine


More than 180 years ago, James Parkinson first described the disorder that bears his name, and 30 years ago levodopa, still the most effective therapy, was introduced. Parkinson's disease is a neurodegenerative disorder of unknown cause that affects over 1 million ...

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Deep brain stimulation for treatment-resistant depression Neuron


Treatment-resistant depression is a severely disabling disorder with no proven treatment options once multiple medications, psychotherapy, and electroconvulsive therapy have failed. Based on our preliminary observation that the subgenual cingulate region ( ...

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The pedunculopontine nucleus and Parkinson's disease Brain


Akinesia and gait disturbances are particularly incapacitating for patients with Parkinson's disease. The anatomical and physiological substrates for these disturbances are poorly understood. The pedunculopontine nucleus (PPN) is thought to be involved in ...

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Randomized controlled trial of intraputamenal glial cell line–derived neurotrophic factor infusion in Parkinson disease Annals of Neurology


Glial cell line–derived neurotrophic factor (GDNF) exerts potent trophic influence on midbrain dopaminergic neurons. This randomized controlled clinical trial was designed to confirm initial clinical benefits observed in a small, open-label trial using intraputamenal ...

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Neuropsychological consequences of chronic bilateral stimulation of the subthalamic nucleus in Parkinson's disease Brain


The aim of this study was to examine possible neuropsychological changes in patients with advanced idiopathic Parkinson's disease treated with bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN). Eleven patients (age= 67±8 years, ...

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