Dr. Eva Polverino is a pulmonologist expert in respiratory infections affiliated with the European Respiratory Society.
Industry Expertise (3)
Areas of Expertise (3)
University of Pisa: M.D., Medicine, Pulmonary Disease Residency Program 2002
- European Respiratory Society
Featured Articles (5)
Importance In patients with severe community-acquired pneumonia, treatment failure is associated with excessive inflammatory response and worse outcomes. Corticosteroids may modulate cytokine release in these patients, but the benefit of this adjunctive therapy remains controversial.
This phase II, randomised, double-blind, multicentre study (NCT00930982) investigated the safety and efficacy of ciprofloxacin dry powder for inhalation (DPI) in patients with non-cystic fibrosis bronchiectasis.
The distribution of the microbial aetiology and mortality of community-acquired pneumonia (CAP) was investigated in relation to the clinical setting and severity scores (pneumonia severity index (PSI) and confusion, blood urea nitrogen, respiratory rate, blood pressure, age (CURB-65).
Since the first British Thoracic Society (BTS) recommendations published in 2002 and web update in 2004, data from several studies have confirmed previous findings suggesting that neither resting sea level oxygen saturations nor forced expiratory volume in 1 s (FEV1) reliably predict hypoxaemia or complications of air travel in passengers with respiratory disease. It is thus now clear that there is no reliable threshold in these variables to determine accurately the safety of air travel or need for in-flight oxygen in an individual patient. Nevertheless, the need for practical recommendations remains. The new guidance covers bronchiectasis, cancer, hyperventilation and dysfunctional breathing, obesity, pulmonary arteriovenous malformations and sinus and middle ear disease, and has expanded sections on infection and comorbidity with cardiac disease.
The recent Infectious Disease Society of America/American Thoracic Society guidelines for the management of community-acquired pneumonia (CAP) in adults defined a predictive rule to identify patients with severe CAP to determine the need for intensive care unit (ICU) admission. We clinically validated this rule.