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Dr. John Muscedere - International Federation on Ageing. Kingston, ON, CA

Dr. John Muscedere Dr. John Muscedere

Professor of Medicine | Queen’s University

Kingston, ON, CANADA

Dr. John Muscedere MD, FRCPC is a Professor of Medicine at Queen’s University and an Intensivist at Kingston Health Sciences Center.

Media

Publications:

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Photos:

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Videos:

Combating Frailty (w/ Dr. John Muscedere, Canadian Frailty Network) AVOID Frailty How can we overcome an ageist healthcare system?

Audio:

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Biography

Dr. John Muscedere MD, FRCPC is a Professor of Medicine at Queen’s University and an Intensivist at Kingston Health Sciences Center in Kingston, Ontario Canada. He is the Research Director for the Department of Critical Care Medicine. Dr. Muscedere has extensive experience in clinical research, both in investigator initiated and industry sponsored research. His research focuses on nosocomial infections, systematic reviews and meta-analyses, clinical trials and the impact of frailty on critical care outcomes.

He is the Scientific Director for the Networks of Centers of Excellence (NCE) funded Canadian Frailty Network (CFN). CFN is dedicated to improving care for older Canadians living with frailly through the generation of new knowledge, knowledge mobilization, development of partnerships and training the next generation of highly qualified personnel.

Areas of Expertise (5)

Intensive Care

Healthy Aging

Critical Care

Frailty

Aging

Education (4)

University of Western Ontario: MD 1985

University of Toronto: Specialist Certification, Internal Medicine 1989

University of Toronto: Subspecialty Certification, Respiratory Medicine 1992

University of Toronto: Subspecialty Certification, Critical Care Medicine 1992

Affiliations (3)

  • Queen’s University
  • Kingston Health Sciences Centre
  • Canadian Critical Care Trials Group

Media Appearances (3)

Long-Term Care Is 'Dangerous.' What’s Ontario’s Plan For Alternatives?

HuffPost  online

2020-12-25

Frailty — a state of increased vulnerability and loss of function — and dementia are not inevitable parts of aging, John Muscedere, a professor of critical care medicine at Queen’s University and the scientific director of the Canadian Frailty Network, told HuffPost.

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Health Canada Grants Emergency Use Authorization for N8 Medical CeraShield™ Endotracheal Tubes in Mechanically Ventilated COVID-19 Patients

Canada NewsWire  online

2020-04-02

N8 Medical, LLC (N8 Medical) today announced that Health Canada has granted Dr. John Muscedere of Kingston General Hospital's emergency request to begin using the N8 Medical CeraShield™ Endotracheal Tubes in mechanically-ventilated COVID-19 patients.

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How improving healthcare for the frail elderly can also cut costs

EvidenceNetwork  online

Medical frailty already affects over one million Canadians. It can be expensive and upsetting for frail people and their loved ones. Dr. John Muscedere explains how Canada’s healthcare system can better support frail people, who are typically elderly and more vulnerable.

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Featured Articles (5)

The impact of frailty on intensive care unit outcomes: a systematic review and meta-analysis

National Library of Medicine

John Muscedere, Braden Waters, Aditya Varambally, Sean M Bagshaw, J Gordon Boyd, David Maslove, Stephanie Sibley, Kenneth Rockwood

2017-07-04

Abstract Purpose: Functional status and chronic health status are important baseline characteristics of critically ill patients. The assessment of frailty on admission to the intensive care unit (ICU) may provide objective, prognostic information on baseline health. To determine the impact of frailty on the outcome of critically ill patients, we performed a systematic review and meta-analysis comparing clinical outcomes in frail and non-frail patients admitted to ICU.

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Physical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management

National Library of Medicine

E Dent, J E Morley, A J Cruz-Jentoft, L Woodhouse, L Rodríguez-Mañas, L P Fried, J Woo, I Aprahamian, A Sanford, J Lundy, F Landi, J Beilby, F C Martin, J M Bauer, L Ferrucci, R A Merchant, B Dong, H Arai, E O Hoogendijk, C W Won, A Abbatecola, T Cederholm, T Strandberg, L M Gutiérrez Robledo, L Flicker, S Bhasin, M Aubertin-Leheudre, H A Bischoff-Ferrari, J M Guralnik, J Muscedere, M Pahor, J Ruiz, A M Negm, J Y Reginster, D L Waters, B Vellas

2019-10-03

Abstract Objective: The task force of the International Conference of Frailty and Sarcopenia Research (ICFSR) developed these clinical practice guidelines to overview the current evidence-base and to provide recommendations for the identification and management of frailty in older adults.

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Carbapenem Antibiotics for the Empiric Treatment of Nosocomial Pneumonia: A Systematic Review and Meta-Analysis

National Library of Medicine

Mackenzie Howatt, Michael Klompas, Andre C Kalil , Mark L Metersky, John Muscedere

2019-10-23

Abstract Background: Previous meta-analyses suggested that treating hospital-acquired pneumonia (HAP), including ventilator-associated pneumonia (VAP), with empiric carbapenems was associated with lower mortality rates but higher rates of clinical failure for pseudomonal pneumonia. This study was an updated meta-analysis with sensitivity analyses and meta-regression to better understand the impact of carbapenem use in HAP/VAP.

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Moving Towards Common Data Elements and Core Outcome Measures in Frailty Research

National Library of Medicine

J Muscedere, J Afilalo, I Araujo de Carvalho, M Cesari, A Clegg, H E Eriksen, K R Evans, G Heckman, J P Hirdes, P M Kim, B Laffon, J Lynn, F Martin, J C Prorok, K Rockwood, L Rodrigues Mañas, D Rolfson, G Shaw, B Shea, S Sinha, O Theou, P Tugwell, V Valdiglesias, B Vellas, N Veronese, L M K Wallace, P R Williamson

2019-12-19

Abstract With aging populations around the world, frailty is becoming more prevalent increasing the need for health systems and social systems to deliver optimal evidence based care. However, in spite of the growing number of frailty publications, high-quality evidence for decision making is often lacking. Inadequate descriptions of the populations enrolled including frailty severity and frailty conceptualization, lack of use of validated frailty assessment tools, utilization of different frailty instruments between studies, and variation in reported outcomes impairs the ability to interpret, generalize and implement the research findings. The utilization of common data elements (CDEs) and core outcome measures (COMs) in clinical trials is increasingly being adopted to address such concerns. To catalyze the development and use of CDEs and COMs for future frailty studies, the Canadian Frailty Network (www.cfn-nce.ca; CFN), a not-for-profit pan-Canadian nationally-funded research network, convened an international group of experts to examine the issue and plan the path forward. The meeting was structured to allow for an examination of current frailty evidence, ability to learn from other COMs and CDEs initiatives, discussions about specific considerations for frailty COMs and CDEs and finally the identification of the necessary steps for a COMs and CDEs consensus initiative going forward. It was agreed at the onset of the meeting that a statement based on the meeting would be published and herein we report the statement.

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Physical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management

National Library of Medicine

E Dent, J E Morley, A J Cruz-Jentoft, L Woodhouse, L Rodríguez-Mañas, L P Fried, J Woo, I Aprahamian, A Sanford, J Lundy, F Landi, J Beilby, F C Martin, J M Bauer, L Ferrucci, R A Merchant, B Dong, H Arai, E O Hoogendijk, C W Won, A Abbatecola, T Cederholm, T Strandberg, L M Gutiérrez Robledo, L Flicker, S Bhasin, M Aubertin-Leheudre, H A Bischoff-Ferrari, J M Guralnik, J Muscedere, M Pahor, J Ruiz, A M Negm, J Y Reginster, D L Waters, B Vellas

2019-10-03

Abstract Objective: The task force of the International Conference of Frailty and Sarcopenia Research (ICFSR) developed these clinical practice guidelines to overview the current evidence-base and to provide recommendations for the identification and management of frailty in older adults.

view more