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Dr. Phyllis Billia - University Health Network. Toronto, ON, CA

Dr. Phyllis Billia Dr. Phyllis Billia

Scientist, Toronto General Research Institute | University Health Network

Toronto, ON, CANADA

Dr. Filio Billia is a member of the Division of Cardiology at the University Health Network.





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Dr. Filio Billia is a member of the Division of Cardiology at the University health Network and a Scientist at the Toronto General Research Institute. She completed her medical and research training at the University of Toronto. Recently she completed a post-doctoral fellowship with the world-renowned Dr. Tak W. Mak at the Campbell Family Institute for Cancer Research. She currently is the co-Director of the Peter Munk Cardiovascular Biobank and Medical Director of the Mechanical Circulatory Assist Program. She has embarked in her own research career with funding from the Canadian Institutes of Health Research.

Industry Expertise (2)

Research Medical/Dental Practice

Areas of Expertise (5)

Cardiology Heart Disease and Stroke Heart Transplantation Heart Failure Cardiac Regeneration

Accomplishments (1)

Young Investigator Award


Education (2)

University of Toronto: M.D., Medicine 2011

University of Toronto: Ph.D., Cardiology 2007

Languages (2)

  • Greek
  • English

Media Appearances (4)

Cancer Research Opens Doors to New Heart Therapies

UHN News  


Dr. Phyllis Billia and her team of researchers have shown that heart cell regeneration is possible – but that a heart cell’s ability to regenerate is s​uppressed by​ natural "roadblocks".

It’s believed that if these roadblocks can be removed, heart cells would be able to regenerate and multiply, potentially repairing damage caused by an injury – like a heart attack – to the hear​t.

“Something prevents heart muscle cells from regenerating,” said Dr. Billia. “So, when the heart’s cells are damaged, the effect is irreversible.”...

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Heart transplant saves Krystina’s life, but fight for survival was just beginning

The Hamilton Spectator  


Henniker asked her physician, Dr. Filio (Phyllis) Billia, to hold her hand on the way to the operating room. Billia told her she would be OK...

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Krinos Taste of the Danforth 2014

PR Newswire  


GreekTown has also donated to Dr. Phyllis Billia's cancer research at Toronto General and Toronto Western Hospitals. GreekTown naturally supports a number of Greek initiatives, including donating to University of Toronto's Greek studies program, the Greek Community, the Hellenic Canadian Federation of Ontario, Nefeli (theatre and dance), Greek Orthodox Community of Mississauga, and Hellenic Home for the Aged...

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Heart scientists discover protein that may be 1 cause of heart failure



"Our research suggests that PINK1 is an important switch that sets off a cascade of events affecting heart cell metabolism," says Dr. Phyllis Billia, principal author, clinician‑scientist and heart failure specialist at the Peter Munk Cardiac Centre. "This could be one of the inciting events in the development of heart failure."...

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Articles (5)

Short-term disruption of diurnal rhythms after murine myocardial infarction adversely affects long-term myocardial structure and function Circulation Research


Patients in intensive care units are disconnected from their natural environment. Synchrony between environmental diurnal rhythms and intracellular circadian rhythms is essential for normal organ biology; disruption causes pathology. Whether ...

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Transcatheter Aortic Valve Implantation and Left Ventricular Assist Device: A Word of Caution The Annals of Thoracic Surgery


Aortic valve disease in the setting of a left ventricular assist device presents unique challenges. We present the case of a patient who underwent transcatheter aortic valve implantation to replace a stenotic aortic valve to facilitate left ventricular assist device explantation...

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A glucagon-like peptide-1 analog reverses the molecular pathology and cardiac dysfunction of a mouse model of obesity Circulation


Cardiac consequences of obesity include inflammation, hypertrophy, and compromised energy metabolism. Glucagon-like peptide-1 is an incretin hormone capable of cytoprotective actions that reduces inflammation and endoplasmic reticulum stress in ...

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Parkinson-susceptibility gene DJ-1/PARK7 protects the murine heart from oxidative damage in vivo Proceedings of the National Academy of Sciences


Oxidative stress is caused by an imbalance between the production of reactive oxygen species (ROS) and the ability of an organism to eliminate these toxic intermediates. Although the Parkinson-susceptibility gene, Parkinson protein 7/DJ-1 (DJ-1), has been ...

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Clinical differences between continuous flow ventricular assist devices: a comparison between HeartMate II and HeartWare HVAD Journal of Cardiac Surgery


The HeartWare ventricular assist device (HVAD) is a new generation centrifugal flow VAD recently introduced in Canada. The objective of this study was to compare the HVAD device to the HeartMate II (HMII) axial flow device. Very few studies have compared ...

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