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Dr. Vera Bril - University Health Network. Toronto, ON, CA

Dr. Vera Bril Dr. Vera Bril

Medical Director - Krembil Neuroscience Centre | University Health Network

Toronto, ON, CANADA

Neurologist and researcher focused on the diagnosis and management of patients with complex neuromuscular disorders

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Dr. Vera Bril Publication

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AAN Issues New Guidelines on Best Treatments for Diabetic Nerve Pain

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Biography

Dr. Vera Bril is a Professor of Medicine (Neurology) at the University of Toronto, Director of Neurology at University Health Network and Mount Sinai Hospital and the Krembil Family Chair in Neurology. She has particular expertise in the diagnosis and management of patients with complex neuromuscular disorders. Her research interests have centred on the diagnosis and evidence-based treatment of myasthenia gravis, inflammatory polyneuropathies, and diabetic sensorimotor polyneuropathy. Her work has helped set the standards for electrophysiological investigations in the definition and evaluation of the progression of chronic polyneuropathies. Her research has helped establish the role of intravenous immunoglobulin in the treatment of myasthenia gravis and the Guillain-Barr Syndrome, and the long-term treatment of chronic inflammatory demyelinating polyneuropathy. She has acted in an advisory capacity to Health Canada and the FDA.

Dr. Bril also serves as the Deputy Physician-in-Chief for Economic Affairs for the Department of Medicine at University Health Network and Mount Sinai Hospital and Chair of the Economics committee. She is part of the Department of Medicine Executive Committee and helps administer this group of 300 physicians.

Industry Expertise (6)

Education/Learning Health Care - Services Health Care - Providers Health Care - Facilities Health and Wellness Research

Areas of Expertise (10)

Neurology Neuromuscular Disorders Myasthenia Gravis Inflammatory Polyneuropathies Diabetic Sensorimotor Polyneuropathy Guillan-Barr Syndrome Chronic Polyneuropathies Neural and Sensory Sciences Intravenous Immunoglobulin Chronic Inflammatory Demyelinating Polyneuropathy (Cidp)

Affiliations (6)

  • University of Toronto : Professor, Department of Medicine (Neurology)
  • University Health Network and Mount Sinai Hospital: Head, Division of Neurology
  • Neuromuscular Program: Director
  • Krembil Family Chair in Neurology
  • University Health Network and Mount Sinai Hospital: Deputy Physician-in-Chief, Economic Affairs, Department of Medicine
  • Economics committee: Chair

Media Appearances (3)

Dr Vera Bril places “first-in-class” in Canadian Diabetes Association research granting competition

The Brain Campaign  online

2014-01-01

The Competition for peer reviewed research funding is fierce. Countless researchers around the country, and in some cases, the world, work for months preparing grant funding requests; defend their applications before committees made up of national and international experts and people living the respective disease; and answer detailed questions about their submission to receive scarce funding for their research projects...

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Dr. M. Barbara Berner establishes Fellowship

UHN General & Western Hospital Foundation  online

2014-01-01

Treated by Dr. Vera Bril, leader of the Neuromuscular Clinic at UHN, ever since, Dr. Berner recently expressed her gratitude profoundly. By funding both a fellowship in neuromuscular research – as well as confirming an annual gift to support the current fellowship, and leaving a more significant gift in her Will to support the fellowship in perpetuity – Dr. Berner's support promises to make a sizable difference in MG treatments, both now and into the future...

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Neurology Podcast

American Academy of Neurology  online

2012-10-02

This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns with Dr. Paola Sandroni about her paper on orthostatic intolerance. Dr. Jennifer Fugate is reading our e-Pearl of the week about bright tongue sign. In the next part of the podcast Dr. Ted Burns interviews Dr. Vera Bril about symptomatic treatment of painful diabetic neuropathy...

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Event Appearances (1)

Diagnosis and Management of CIDP

CBS/CIDP Douncation of Canada, National Conference  Toronto, ON.

2009-04-18

Articles (6)

Evidence-based guideline: Treatment of painful diabetic neuropathy American Academy of Neurology

2011-01-01

The basic question asked was: “What is the efficacy of a given treatment (pharmacological: anticonvulsants, antidepressants, opioids, others; and non-pharmacological: electrical stimulation, magnetic field treatment, low-intensity laser treatment, Reiki massage, others) to reduce pain and improve physical function and quality of life (QOL) in patients with PDN?”

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Intravenous immune globulin (10% caprylate-chromatography purified) for the treatment of chronic inflammatory demyelinating polyradiculoneuropathy (ICE study): a randomised placebo-controlled trial The Lancet

2008-01-01

Short-term studies suggest that intravenous immunoglobulin might reduce disability caused by chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) but long-term effects have not been shown. We aimed to establish whether 10% caprylate- ...

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Diabetic Neuropathies : A Statement by the American Diabetes Association American Diabetes Association

2005-01-01

The diabetic neuropathies are hetero-geneous, affecting different parts of the nervous system that present with diverse clinical manifestations. They may be focal or diffuse. Most common among the neuropathies are chronic sensorimotor distal symmetric ...

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Simple screening tests for peripheral neuropathy in the diabetes clinic Diabetes Care

2001-01-01

The utility of rapid and reliable sensory tests appropriate for the diagnosis of neuropathy in the diabetes clinic, rather than as prognostic tools for the prediction of foot complications, has been unclear because of limitations inherent in previous studies. ...

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Regeneration and Repair of Myelinated Fibers in Sural-Nerve Biopsy Specimens from Patients with Diabetic Neuropathy Treated with Sorbinil The New England Journal of Medicine

1988-01-01

There is reason to believe that diabetic neuropathy may be related to the accumulation of sorbitol in nerve tissue through an aldose reductase pathway from glucose. Short-term treatment with aldose reductase inhibitors improves nerve conduction in ...

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Histopathological heterogeneity of neuropathy in insulin-dependent and non-insulin-dependent diabetes, and demonstration of axo-glial dysjunction in human diabetic neuropathy The Journal of Clinical Investigation

1988-01-01

Altered sorbitol and myo-inositol metabolism,(Na, K)-ATPase function, electrochemical sodium gradients, axonal swelling, and distortion and disruption of the node of Ranvier (" axo-glial dysjunction") directly implicate hyperglycemia in the pathogenesis ...

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