Guogen Shan
Professor | University of Florida
Gainesville, FL, UNITED STATES
Guogen Shan is an expert in longitudinal data analysis, cognitive neuroscience, and clinical trial design and analysis.
Biography
Guogen Shan is a professor biostatistics, interim director of the Research Design and Data Coordinating Center, and
director of the Biostatistics Consulting Lab.
Areas of Expertise (4)
Alzheimer's Disease
Longitudinal Data Analysis
Clinical Trials Design & Analysis
Cognitive Neuroscience
Articles (3)
Conversion to Alzheimer's disease dementia from normal cognition directly or with the intermediate mild cognitive impairment stage
Alzheimer's & Dementia JournalXinlin Lu, et. al
2025-01-21
Progression to Alzheimer's disease (AD) dementia from normal cognition (NC) can follow different trajectories, with most progressing through a recognizable mild cognitive impairment stage (NC-MCI-AD), while some individuals transition quickly from NC to AD dementia (NC-AD).
ADSS: A Composite Score to Detect Disease Progression in Alzheimer's Disease
Journal of Alzheimer's Disease ReportsGuogen Shan, et. al
2024-02-20
Composite scores have been increasingly used in trials for Alzheimer's disease (AD) to detect disease progression, such as the AD Composite Score (ADCOMS) in the lecanemab trial.
Comparison of Pocock and Simon's covariate-adaptive randomization procedures in clinical trials
BMC Medical Research MethodologyGuogen Shan, et. al
2024-01-25
When multiple influential covariates need to be balanced during a clinical trial, stratified blocked randomization and covariate-adaptive randomization procedures are frequently used in trials to prevent bias and enhance the validity of data analysis results.
