Ho Ming Chow

Associate Professor, Communication Sciences & Disorders University of Delaware

  • Newark DE

Ho Ming Chow studies developmental stuttering and other speech disorders.

Contact

University of Delaware

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Media

Biography

Dr. Chow received his Bachelor’s and Master’s Degrees in Engineering at the University of Hong Kong. After working as an engineer for few years, he became interested in studying human cognition and went to Germany for his doctoral study. He obtained his PhD. in Cognitive Sciences with an emphasis on Cognitive Psychology at the University of Osnabrück. He completed his postdoctoral training at the National Institutes of Health. Before joining the University of Delaware in 2019, he was a research faculty at the University of Michigan and Nemours Children’s Hospital, Delaware.

Areas of Expertise

Motor Speech Disorders
Neural Correlates of Speech and Language Processing
Neuroimaging Method Development
Imaging Genetics
Epilepsy
Stuttering

Media Appearances

Season 5 - Episode 8: Research Update: Brain developmental trajectories associated with childhood stuttering persistence and recovery

The Stuttering Foundation  online

2023-08-08

Dr. Ho Ming Chow, Assistant Professor at the University of Delaware and principal investigator for the Delaware Stuttering Project, joins host Sara MacIntyre, M.A., CCC-SLP, to discuss a recent article, 'Brain developmental trajectories associated with childhood stuttering persistence and recovery,' in Developmental Cognitive Neuroscience.

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New paper finds brain activity differences associated with stuttering

Speech Neurophysiology Lab  online

2023-05-10

Working in collaboration with Dr. Ho Ming Chow at the University of Delaware, the paper reports new findings on brain activity differences between children who stutter and those who don’t.

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Unraveling the mystery behind stuttering | UDaily

University of Delaware  online

2022-07-27

UD researchers study the brains of children with persistent stuttering to determine what hinders recovery

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Articles

Evidence for planning and motor subtypes of stuttering based on resting state functional connectivity

Brain and Language

2024

We tested the hypothesis, generated from the Gradient Order Directions Into Velocities of Articulators (GODIVA) model, that adults who stutter (AWS) may comprise subtypes based on differing connectivity within the cortico-basal ganglia planning or motor loop. Resting state functional connectivity from 91 AWS and 79 controls was measured for all GODIVA model connections. Based on a principal components analysis, two connections accounted for most of the connectivity variability in AWS: left thalamus – left posterior inferior frontal sulcus (planning loop component) and left supplementary motor area – left ventral premotor cortex (motor loop component). A k-means clustering algorithm using the two connections revealed three clusters of AWS.

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Brain developmental trajectories associated with childhood stuttering persistence and recovery

Developmental Cognitive Neuroscience

2023

Stuttering is a neurodevelopmental disorder affecting 5–8 % of preschool-age children, continuing into adulthood in 1 % of the population. The neural mechanisms underlying persistence and recovery from stuttering remain unclear and little information exists on neurodevelopmental anomalies in children who stutter (CWS) during preschool age, when stuttering symptoms typically first emerge. Here we present findings from the largest longitudinal study of childhood stuttering to date, comparing children with persistent stuttering (pCWS) and those who later recovered from stuttering (rCWS) with age-matched fluent peers, to examine the developmental trajectories of both gray matter volume (GMV) and white matter volume (WMV) using voxel-based morphometry.

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Brain activity during the preparation and production of spontaneous speech in children with persistent stuttering

NeuroImage: Clinical

2023

Speech production forms the basis for human verbal communication. Though fluent speech production is effortless and automatic for most people, it is disrupted in speakers who stutter, who experience difficulties especially during spontaneous speech and at utterance onsets. Brain areas comprising the basal ganglia thalamocortical (BGTC) motor loop have been a focus of interest in the context of stuttering, given this circuit’s critical role in initiating and sequencing connected speech. Despite the importance of better understanding the role of the BGTC motor loop in supporting overt, spontaneous speech production, capturing brain activity during speech has been challenging to date, due to fMRI artifacts associated with severe head motions during speech production.

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Research Grants

“Administrative supplements to fund team science development projects”

NIGMS

2023/02 – 2023/01

“Neural subtypes of developmental stuttering”

NIDCD

2022/04 – 2027/03

“Generating articulatory movement from speech using deep neural network”

NIGMS

2019/12 – 2020/12

Accomplishments

Meritorious Poster Award, American Speech-Language-Hearing Association

2017

NIDCD Early Career Research (ECR) Award R21 (Role: PI)

2016

NIH Fellows Award for Research Excellence

2015

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Education

University of Osnabrueck

PhD

Cognitive Science

2008

University of Hong Kong

MPhil

Ergonomics

2000

University of Hong Kong

BEng

Industrial Engineering

1997

Affiliations

  • Neurobiology of Speech & Language Lab
  • Interpersonal Neurophysiology Lab
  • Center for Bioinformatics & Computational Biology
  • Interdisciplinary Neuroscience Graduate Program

Languages

  • English