John Neubert
Professor | University of Florida
Gainesville, FL, UNITED STATES
John Neubert has clinical and translational research expertise relating to the understanding and treatment of orofacial pain conditions
Biography
John Neubert's overall academic interests primarily involve basic and translational pain research. This research has mainly focused on the role of peripheral mechanisms related to the expression of orofacial pain. Specifically, his laboratory has pioneered the assessment of orofacial pain in rodent models using operant testing paradigms. More recently, Neubert's research interests have shifted to central mechanisms of modulating pain and have included investigating the roles of opioids and cannabinoids on pain and substance use disorders.
Areas of Expertise (4)
Orthodontics
Orofacial Pain
Pain
Temporomandibular Joint (TMJ) Disorders
Articles (3)
An ethogram analysis of cutaneous thermal pain sensitivity and oxycodone reward-related behaviors in rats
Scientific ReportsAriana C. Brice-Tutt, et. al
2023-06-28
Inter-relationships between pain sensitivity, drug reward, and drug misuse are of considerable interest given that many analgesics exhibit misuse potential. Here we studied rats as they underwent a series of pain- and reward-related tests: cutaneous thermal reflex pain, induction and extinction of conditioned place preference to oxycodone (0.56 mg/kg), and finally the impact of neuropathic pain on reflex pain and reinstatement of conditioned place preference.
Imaging the neural substrate of trigeminal neuralgia pain using deep learning
Frontiers in Human NeuroscienceYun Liang, et. al
2023-05-18
Trigeminal neuralgia (TN) is a severe and disabling facial pain condition and is characterized by intermittent, severe, electric shock-like pain in one (or more) trigeminal subdivisions. This pain can be triggered by an innocuous stimulus or can be spontaneous. Presently available therapies for TN include both surgical and pharmacological management; however, the lack of a known etiology for TN contributes to the unpredictable response to treatment and the variability in long-term clinical outcomes.
Preclinical comparison of antinociceptive effects between ibuprofen, diclofenac, naproxen, and acetaminophen on acid-stimulated body stretching and acid-depressed feeding behaviors in rats
Behavioural PharmacologyAhmad A. Altarifi, et. al
2022-12-01
Pain is a major problem that burdens the health and economy of societies worldwide. Nonsteroidal anti-inflammatory drugs (NSAIDs) are over-the-counter medications that are widely indicated for mild to moderate pain conditions. Clinically, the selection of a medication among this class is mainly based according to both patient's and doctor's previous experiences. Herein, we studied differences in therapeutic efficacies among the most commonly prescribed NSAIDs and acetaminophen in inflammatory pain rat...
