Katharina Busl
Professor/Chief | University of Florida
Gainesville, FL, UNITED STATES
Dr. Katharina Busl is a professor of neurology and neurosurgery.
Biography
Dr. Katharina Busl is the chief of the Division of Neurocritical Care, professor, and associate chair of clinical operations in the Department of Neurology. She is an internationally recognized expert in neurocritical care. She has co-authored clinical guidelines for the management of subarachnoid hemorrhage, neuroprognostication guidelines for neurocritical diseases and numerous manuscripts relevant to clinical neurocritical care. Clinical interests include subarachnoid hemorrhage, neuroprognostication, her research interests center around care innovations and quality of care in neurocritical care. Specific interests include treatment of headaches in the NeuroICU, neuroprognostication and medical complications of neurocritical disease. Dr. Busl is the lead PI for BLOCK-SAH, an NIH-funded, multicenter trial to investigate pterygopalatine fossa nerve blocks for post-subarachnoid hemorrhage headaches.
Areas of Expertise (4)
Subarachnoid Hemorrhage
Brain Death
Neurocritical Care
Acute Brain Injury
Articles (3)
Role of Dexmedetomidine in Aneurysmal Subarachnoid Hemorrhage: A Comprehensive Scoping Review
Journal of Neurosurgical AnesthesiologyKatharina M. Busl, et al.
2022-04-01
Dexmedetomidine has been widely used for anesthesia, pain control, and intensive care unit sedation. Subarachnoid hemorrhage is a complex disease that is divided into 2 phases: early brain injury and delayed cerebral ischemia. Dexmedetomidine has been shown to have an effect on these Subarachnoid hemorrhage-related pathologic processes.
Pregabalin for Recurrent Seizures in Critical Illness: A Promising Adjunctive Therapy, Especially for cyclic Seizures
Neurocritical CareKatharina M. Busl, et al.
2022-02-25
Pregabalin is an effective adjunctive treatment for focal epilepsy and acts by binding to the alpha2-delta subunit of voltage-gated calcium channels to reduce excitatory neurotransmitter release. Pregabalin has been shown to increase spreading depolarization threshold; hence, we hypothesized that the magnitude of antiseizure effect from pregabalin is more pronounced in patients with cyclic versus noncyclic seizures in a critically ill cohort with recurrent seizures.
Early vigabatrin augmenting GABA-ergic pathways in post-anoxic status epilepticus (VIGAB-STAT) phase IIa clinical trial study protocol
Neurological Research and PracticeKatharina M. Busl, et al.
2022-01-24
Nearly one in three unconscious cardiac arrest survivors experience post-anoxic status epilepticus. Historically, post-anoxic status epilepticus has been deemed untreatable resulting in its exclusion from status epilepticus clinical trials. However, emerging reports of survivors achieving functional independence following early and aggressive treatment of post-anoxic status epilepticus challenged this widespread therapeutic nihilism.
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