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Maria Jesús Saénz, PhD

Director, MIT Digital Supply Chain Transformation Lab | Executive Director, MIT SCM Masters Programs MIT Center for Transportation & Logistics

  • Cambridge MA

Dr. Saénz focuses on how fast-evolving technologies and AI reshape E2E value chains and Human-AI collaboration.

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Spotlight

2 min

In a recent Supply Chain Management Review article, the work of Dr. María Jesús Sáenz is highlighted through a project that tackled the challenge of optimizing an end-to-end supply chain for a global consumer goods company. The company’s traditional planning model—based on mixed-integer programming—took nearly two hours to compute a full production and distribution plan, making it difficult to respond to real-time changes such as demand fluctuations or material shortages. Dr. Sáenz and her team recognized that this lack of agility was a barrier to efficiency and competitiveness, particularly in today’s volatile global markets. Under Dr. Sáenz’s direction, the research team redesigned the process using a hybrid meta-heuristic approach that combined Genetic Algorithms (GA) and Particle Swarm Optimization (PSO). By breaking down the overall planning task into smaller, more manageable segments, they were able to generate high-quality, near-optimal plans in a fraction of the original computation time—reducing the process from hours to mere minutes. This demonstrated how advanced analytical methods can dramatically improve responsiveness and performance across a company’s entire supply chain. More broadly, Dr. Sáenz’s work underscores that end-to-end optimization is not just a technical challenge but a strategic one. She advocates for supply chains that are not only data-driven but also interconnected across all functions—from sourcing to delivery—so that decisions align with the organization’s overall objectives. Her approach combines operational excellence with digital innovation, showing how companies can build more agile, resilient, and intelligent supply networks capable of thriving amid constant disruption. The SCM thesis Smarter, Faster, Leaner: Optimizing the End-to-End Supply Chain was authored by Javiera Arancibia and Fernanda Esparza and supervised by Dr. María Jesús Sáenz and Dr. Jaime Macías Aguayo. Dr. María Jesús Sáenz is available to speak with reporters regarding this important research simply click on her icon now to arrange an interview today.

Maria Jesús Saénz, PhD

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Biography

Dr. Maria Jesus Saenz is the Executive Director of the MIT Supply Chain Management Master Programs, a #1 worldwide-ranked MIT degree that allows learners innovative educational paths in the supply chain domain, embracing the MIT experience. Dr. Saenz also serves as the director of the MIT Digital Supply Chain Transformation Lab. She explores and quantifies how fast-evolving digital technologies and AI reshape E2E supply chains and identifies the new opportunities behind Human-AI collaboration. The Lab applies quantitative research methodologies to assess how data-driven ecosystems create value.

Dr. Saenz, as a senior lecturer at MIT, teaches various courses at the Master's and Executive Education levels on Digital Transformation, Supply Chain Management, AI-driven Supply Chains, and Human-AI Collective Intelligence. Regarding her education, Dr. Saenz is certified in Leadership for Senior Executives and Participant Centered Learning by Harvard Business School. She received Cum Laude and the Outstanding Doctoral Award for her PhD in Manufacturing and Design Engineering from the University of Zaragoza, where she previously obtained her M.Sc. in Industrial Engineering, while she also studied Mathematical Sciences for several years. In 2003, she received her tenure as Associate Professor in the School of Engineering at the University of Zaragoza. In 2004, she founded the research institute MIT Zaragoza Logistics Center as Professor, and she has also served the Center as its Executive Director. She was also the Director of the Spanish Center of Excellence in Logistics.

Dr. Saenz is a strategic advisor to unicorn startups and also led various international research projects for the European Commission, as well as for companies on Supply Chain transformation, such as Dell, J&J, L’Oreal, Maersk, Coca-Cola Femsa, Mondelez, P&G, Carrefour, DHL, Leroy Merlin, or Caterpillar. She is co-author of more than 100 publications, including books and articles in leading international Journals. Her knowledge transfer work has received 20 awards, and her research was cited in the media, including Harvard Business Review, MIT Sloan Management Review, WSJ, Forbes, Financial Times, and Supply Chain Management Review. She has interacted with business leaders as a guest keynote speaker in more than 15 countries.

Research Focus

Intelligent & Autonomous Supply Chains

AI-driven, data-centric, and increasingly autonomous decision systems for supply chain planning and execution.

Supply Chain Strategy & Network Architecture

Designing the structural configuration and competitive positioning of supply networks.

Areas of Expertise

Digital Transformation
Scaling E2E Automation
AI-Driven Supply Chain
Supply Chain Resilience
Human-AI Collaboration
Autonomous Operations

Education

Harvard Business School

Leadership for Senior Executives

Executive Education

2022

Harvard Business School

Participant-Centered Learning

Executive Education

2014

Universidad de Zaragoza

Ph.D.

Manufacturing and Design Engineering

2000

Affiliations

  • MIT Digital Supply Chain Transformation Lab : Director
  • MIT SCM Masters Programs : Executive Director
  • MITx PRO : Lecturer
  • MIT Professional Education : Lecturer

Languages

  • English
  • Spanish

Media Appearances

How AI is reshaping supply chains

Financial Times  online

2026-07-15

Maria Jesús Saénz, the director of the supply chain transformation lab at the Massachusetts Institute of Technology, says AI means that supply chains can be automated and autonomous. “This is a vision for most companies [but] the reality for only a few of them – the most successful ones,” she says.

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How AI Is Reshaping Supplier Negotiations

Harvard Business Review  online

2025-07-24

AI is starting to play a major role in how companies negotiate with suppliers. These advancements are driven by the need for greater speed, scalability, and strategic agility due to increasingly complex supply chains and disruptions caused by external factors such as weather and trade wars. Once a cost-saving tool for automating low-value, repetitive negotiations, AI is now being used to make key decisions in procurement.

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Opening pathways for future supply chain leaders

MIT News  online

2023-10-20

Sit down with Maria Jesus Saenz of the MIT Center for Transportation and Logistics (CTL) to discuss her professional achievements and priorities, and you’re likely to come away with two questions: How has she become a thought leader in so many areas — from logistics strategies and supply chain education to human-AI collaboration and digital supply chain transformation, to name just a few? And what is behind her legendary energy and drive?

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Speaking Engagements/Featured Conversations

Human-AI Collaboration: Boosting Supply Chain Performance

Drawing on her MIT research, Dr. María Jesús Saénz explains how to design effective human–AI partnerships in supply chains. She outlines where AI adds the most value (forecasting, learning loops, autonomous negotiations), how to build the right data and talent foundations, and practical ways to optimize long-term performance while proactively managing human and algorithmic bias. Watch the full episode: https://www.youtube.com/watch?v=5ij0b9-Xkqk

Revolutionizing Supply Chains: How MIT Harnesses Data and Tech w/ Maria Jesus Saenz

In this video, MIT's Maria Jesus Saenz talks about how data and technology are changing supply chain relationships – and how this is having a profound effect on the way we do business. As companies move away from traditional methods of doing business and towards ecosystems and data-driven approaches, supply chain relationships are changing dramatically. Sanez shares with you some of the consequences of this shift, and discuss the ways in which companies are preparing for the future. Watch the full episode: https://www.youtube.com/watch?v=EeY4s8L-2qU

Key Performance and Key Learning Indicators in Digital Transformation

Sáenz shares examples of how companies may use AI and ML to collaborate on data models and leverage publicly available data to craft more accurate forecasts or discover hidden efficiencies. Watch the full episode: https://www.youtube.com/watch?v=rNWzjt2j7KU

Research Papers

Integrating AI in organizations for value creation through Human-AI teaming: A dynamic-capabilities approach

Journal of Business Research

2024-09-01

Although the potentialities of artificial intelligence (AI) are motivating its fast integration in organizations, our knowledge on how to capture organizational value out of these investments is still scarce. Relying on an approach to dynamic capabilities that focuses on the team level, we examine how humans and AI create interactions that engage both agents in productive dialogue for value co-creation.

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Human–Artificial Intelligence Collaboration in Prediction: A Field Experiment in the Retail Industry

Journal of Management Information Systems

2023-12-11

This study investigates the role of human intervention in artificial intelligence/machine learning (AIML)-driven predictions. By doing so, we distinguish between three different types of human-AIML collaboration: automation, adjustable automation, and augmentation.

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From natural language to simulations: applying AI to automate simulation modelling of logistics systems

International Journal of Production Research

2023-11-02

Our research strives to examine how simulation models of logistics systems can be produced automatically from verbal descriptions in natural language and how human experts and artificial intelligence (AI)-based systems can collaborate in the domain of simulation modelling. We demonstrate that a framework constructed upon the refined GPT-3 Codex is capable of generating functionally valid simulations for queuing and inventory management systems when provided with a verbal explanation.

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Event Appearances

Human-AI Collaboration: Boosting Supply Chain Performance

June 2025 | DPW/New York  

Awards

Best Paper Award

Issued by Operations Management Research
2025

Bestseller Case Study

Issued by Harvard Business Publishing
2025

Women in Supply Chain Award

Sep 2023

Courses

SCM.261 Supply Chain Transformation: Case Studies

A combination of case studies and industry speakers covering the strategic and operating issues in supply chain transformation. Focuses on the pragmatic creation of supply chain capabilities, including resilience, omnichannel, E2E visibility, entrepreneurship, servitization, E2E automation, and AI.

MIT CTL Executive Education: E2E Autonomous Supply Chains

[no description available]

MITx PRO: COO Supply Chain Management: Leading with AI and Digital Transformation

[no description available]