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Michele Marcolongo, PhD, PE

Drosdick Endowed Dean and Professor of Mechanical Engineering Villanova University

  • Villanova PA

Michele Marcolongo, PhD, PE, is an expert in biomaterials and engineered biomedical solutions to treat disease.

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Areas of Expertise

Engineering Education and Research
University Leadership
Medical Devices
Back Pain
Biomaterials
Engineered Biomedical Solutions
Molecular engineering
Materials Science
Arthritis Treatments
Cartilage
Entrepreneurship
Mentoring

Biography

Michele Marcolongo, PhD, PE, is the Drosdick Endowed Dean of Villanova University's College of Engineering and Professor of Mechanical Engineering. In this role, Dr. Marcolongo provides vision and leadership for the college's long-term strategic and academic goals, and she is committed to enhancing both faculty research and teaching innovation.

Dr. Marcolongo's research focuses on biomaterials and engineered biomedical solutions to treat disease. She was named a fellow of the National Academy of Inventors and the American Institute for Medical and Biological Engineering, and her research has been funded by top agencies such as the National Science Foundation, the National Institutes of Health, the US Department of Defense and the US Department of Education. Dr. Marcolongo serves on the editorial boards of the Journal of Biomedical Materials Research and Regenerative Engineering and Translational Medicine, and is the founding president of the Philadelphia Spine Research Society.

In addition to her extensive work in academia, Dr. Marcolongo is a successful entrepreneur who has co-founded three biomedical technology startup companies and is a co-holder of 15 patents/patent applications. Inspired by her experiences in academia and entrepreneurship, she authored a book, Academic Entrepreneurship: How to Bring Your Scientific Product to a Commercial Discovery, which serves as a how-to guide for academic faculty, graduate students and postdoctorals on translating research from the lab to commercialization.

Education

University of Pennsylvania

PhD

Bioengineering

University of Pennsylvania

MS

Bioengineering

Drexel University

MS

Mechanical Engineering

Select Accomplishments

“Start-up Campus” Keynote Address, University of California San Francisco

2026

ELATES Keynote Address to Graduates

2025

Scholar GPS Top Scholar

2024

Affiliations

  • National Academy of Inventors : Fellow
  • American Institute for Medical and Biological Engineering : Fellow
  • Philadelphia Spine Research Society : Founding President
  • Alpha Sigma Mu: Fellow

Select Media Appearances

Purpose, Persistence, and Performance in STEM Leadership

Lead Change Podcast  online

2026-05-11

In this episode of Lead Change, Dr. Michele Marcolongo joins host Mary K. Mulcahey for a powerful conversation about leadership, innovation, mentorship, and purpose-driven work in academia and engineering. The discussion explores her leadership philosophy as Dean of Engineering at Villanova University, including servant leadership, strategic vision-setting, mentorship, and creating a culture of respect and collaboration. Dr. Marcolongo also highlights groundbreaking initiatives at Villanova, including sustainable engineering integration, new biomedical engineering programs, and the innovative Sports and Performance Engineering master’s program.

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Research Grants

Molecular Engineering of Cartilage PCM Mechanotransduction in Osteoarthritis Using Biomimetic Proteoglycans

National Institutes of Health

2022-present

Impact of Perlecan Mimics on Cartilage PCM Biomechanics in Health and Disease

National Science Foundation

2018-2022

GAANN-BIOMAT (Biologically-Inspired Materials: Applications and Theory)

Department of Education

2012-2017

Select Academic Articles

Synthesis of Chondroitin Sulfate Conjugated Nanofiber Shish Kebabs as a Biomimetic Bone Template

Journal of Biomedical Materials Research Part A

2025

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Surface Modification of Polyetheretherketone With Calcium Phosphate Using Ultraviolet Functionalization

Journal of Biomedical Materials Research Part B

2025

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Biomimetic Proteoglycans Strengthen the Pericellular Matrix of Normal and Osteoarthritic Human Cartilage

ACS Biomaterials Science & Engineering Journal

2024

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