Spotlight
Biography
Dr. Nicholas J. Petrelli is a nationally recognized expert on colorectal cancer, joined ChristianaCare as the Bank of America endowed medical director of the Helen F. Graham Cancer Center and Research Institute in August 2001. As medical director, Dr. Petrelli oversees the state’s largest and most technologically advanced cancer program, including cancer detection, diagnosis and treatment. Under his leadership the Graham Cancer Center was selected as a National Cancer Institute Community Oncology Research Program (NCORP) and one of the original 16 NCI Community Cancer Centers Programs (NCCCP).
Dr. Petrelli came to ChristianaCare from one of the nation’s leading NCI Designated Cancer Centers, Roswell Park Cancer Institute in Buffalo, NY, where he led several clinical trials for a promising form of chemotherapy. He has conducted substantial research into the genetics of colorectal cancer and co-authored more than 300 manuscripts in peer-reviewed journals as well as 36 book chapters.
Areas of Expertise (5)
Colorectal Cancer
Cancer Care Management
Cancer Detection
Cancer clinical trials
Surgical Oncology
Education (3)
Tulane University Medical School: MD 1973
University of Notre Dame: BA 1969
Roswell Park Cancer Institute: Surgical Oncology Fellowship
1978-1980
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Links and Image Galleries (3)
Media Appearances (3)
Petrelli receives Tilton Award from Medical Society of Delaware
Dover Post
2019-10-10
Nicholas J. Petrelli, Bank of America endowed medical director of ChristianaCare’s Helen F. Graham Cancer Center & Research Institute, received the Tilton Award from the Medical Society of Delaware on Oct. 4.
Delaware-developed CRISPR cancer therapy edging closer to human testing
Philadelphia Business Journal
2019-05-06
Dr. Nicholas J. Petrelli, medical director of the Helen F. Graham Cancer Center & Research Institute at ChristianaCare, said the study — if approved — would put the Wilmington health system in a position to capture a trio of firsts. “It will be the first lung cancer clinical trial carried out by a gene editing program embedded in a community cancer center,” Petrelli said. “While our Gene Editing Institute has a great deal of translational research experience, this will be its first study to move scientific discovery toward an IND. And, it will also be the first time that we will be investigating technology that was grown organically at the Gene Editing Institute.”...
ChristianaCare’s Gene Editing Institute takes the next step toward its first investigational drug application for FDA approval to treat lung cancer using CRISPR
BioSpace
2019-04-30
“This exciting study represents a trio of firsts,” said Nicholas J. Petrelli, M.D., FACS, Bank of America endowed medical director of the Helen F. Graham Cancer Center & Research Institute at ChristianaCare. “It will be the first lung cancer clinical trial carried out by a gene editing program embedded in a community cancer center. While our Gene Editing Institute has a great deal of translational research experience, this will be its first study to move scientific discovery toward an IND application. And, it will also be the first time that we will be investigating technology that was grown organically at the Gene Editing Institute.”
Selected Papers and Publications (6)
High volume pancreaticoduodenectomy performed at an academic community cancer center
American Journal of Surgery, 218(2): 349 -354Sabesan A, Gough B, Anderson C, Abdel-Misih RZ, Petrelli NJ, Bennett JJ.
2019
Folates as adjuvants to anticancer agents: chemical rationale and mechanism of action
Critical Reviews in Hematology/Oncology, 106: 118-131Danenberg P, Gustavsson B, Johnston P, Lundberg P, Moser R, Odin E. Peters G, Petrelli N.
2016.
Operative approach to rectal cancer: an anatomical and technical description
Surgical Oncology: 27(2)Khatri VP, Rodrigues-Bigas MA, Flewell R, Petrelli NJ.
2018
The impact of multidisciplinary care on processes of cancer care: a multi institutional study
Journal of Oncology Practice, 12(2): 155-156Onukwugha E, Petrelli N, Castro K, Gardner J, Jayasekera J, Gohoubava O, Tan M, McNamara E, Zaren HA, Asfeldt T, Bearden J, Salner A, Krasna MJ, Praghu D, Clauser SB.
2016
A review of the evolution of systemic therapy in the management of colorectal cancer
Clinical Colorectal Cancer, 14(1), 1-10Gustavsson CG, Machover D, Petrelli N, Roth A, Schmoll H, Tveit K, Gibson F.
2015
Responsibility for costs associated with clinical trials
J Clin Oncol, 32(30): 3357-59Martin P, Ennis N, Petrelli N, Stewart F, Appelbaum F, Benson A.
2014
External Service & Affiliations (3)
- Annals of Surgical Oncology : Associate Editor
- Surgical Oncology Clinics of North America : Editor
- Surgical Oncology : Co-Editor
Selected Honors & Awards (3)
Clinical Research Award
2014 Association of Community Cancer Centers
American Cancer Society Clinical Oncology Fellowship Award
1980
American Cancer Society Clinical Oncology Fellowship Award
1979
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