
Noelle Comolli, PhD
Professor of Chemical and Biological Engineering; Associate Dean for Faculty Affairs | College of Engineering Villanova University
- Villanova PA
Noelle Comolli, PhD, researches the use of different polymers for either novel biomaterials or controlled release delivery vehicles.
Social
Areas of Expertise
Biography
Education
Drexel University
PhD
University of Delaware
BS
Select Media Appearances
Nanoparticle Platform Delivers Drugs Across Blood-Brain Barrier in Mice
Medscape (Reuters Health) print
2021-01-15
A novel nanoparticle drug delivery system had a therapeutic effect in a mouse model of traumatic brain injury (TBI), regardless of whether the blood-brain barrier (BBB) was physically breached or intact, researchers say.
Dr. Noelle Comolli, Chair of Chemical Engineering at Villanova University in Pennsylvania, commented by email, "These nanoparticle platforms are becoming increasingly common, and similar to the lipid nanoparticle coating used in the new mRNA vaccines for COVID. These show great promise, since the increased permeability can be used in so many applications, not just TBI."
Select Academic Articles
Synthesis and characterization of multi-targeted polymeric antibody-microparticle conjugates with controlled drug release
International Journal of Polymeric Materials and Polymeric BiomaterialsLucia Fernandez, Shannon Oakes, John Cipullo, Cole Moros, Jenna Hofman & Noelle Comolli
2024
Evaluation of Acetaminophen Release from Biodegradable Poly (Vinyl Alcohol) (PVA) and Nanocellulose Films Using a Multiphase Release Mechanism
NanomaterialsKelsey L. O’Donnell, Gloria S. Oporto-Velásquez and Noelle Comolli
2021
Chemotherapeutic loading via tailoring of drug-carrier interactions in poly (sialic acid) micelles
AIMS BioengineeringGerald Pawlish, Kyle Spivack, Adam Gabriel, Zuyi Huang, Noelle Comolli
2018