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Sandro R. P. da Rocha, Ph.D. - VCU College of Engineering. Smith Building, Room 450A, Richmond, VA, US

Sandro R. P. da Rocha, Ph.D. Sandro R. P. da Rocha, Ph.D.

Associate Professor, Department of Chemical and Life Sciences Engineering | VCU College of Engineering

Smith Building, Room 450A, Richmond, VA, UNITED STATES

Dr. da Rocha specializes in chemical engineering, biomedical engineering and nanotechnology.

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Industry Expertise (2)

Research

Education/Learning

Areas of Expertise (5)

Nanomedicine

Nonivasive Drug & Gene Delivery

Biomaterials

Cancer nanotechnology

Aerosol formulation

Education (4)

University of Texas at Austin: Postdoc, Chemistry & Biochemistry

University of Texas at Austin: Ph.D., Chemical Engineering

Federal University of Santa Catarina (Brazil): M.S., Chemical Engineering

Federal University of Santa Maria (Brazil): B.S., Chemical Engineering

Affiliations (4)

  • Frontiers in Colloidal Materials and Interfaces
  • Journal of Pharmaceutics
  • Advances in Pharmaceutics
  • Chemical Engineering and Process Techniques

Media Appearances (1)

VCU launches Center for Pharmaceutical Engineering and Sciences

Virginia Business  online

2019-04-16

“The idea is to translate this new knowledge and discoveries into real products,” says Sandro R.P. da Rocha, a professor in the School of Pharmacy.

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Selected Articles (3)

Poly(amidoamine) Dendrimer–Doxorubicin Conjugates: In Vitro Characteristics and Pseudosolution Formulation in Pressurized Metered-Dose Inhalers Molecular Pharmaceutics

2016 Lung cancers are the leading cause of cancer death for both men and women. A series of PEGylated poly(amidoamine) dendrimer-based doxorubicin (DOX) nanocarriers (G3NH2-mPEG-nDOX) were synthesized and their chemistry tailored for the development of novel pseudosolution formulations in propellant-based metered-dose inhalers (pMDIs) with enhanced aerosol characteristics.

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Effect of the Conjugation Density of Triphenylphosphonium Cation on the Mitochondrial Targeting of Poly(amidoamine) Dendrimers Molecular Pharmaceutics

2015 Many clinically relevant diseases with known poor therapeutic outcomes, including cancer and neurodegenerative disorders, have been directly linked to mitochondrial dysfunction. The ability to efficiently target therapeutics to intracellular organelles such as mitochondria may represent new opportunities for the effective treatment of such ailments.

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Poly(amidoamine) Dendrimer Nanocarriers and Their Aerosol Formulations for siRNA Delivery to the Lung Epithelium Molecular Pharmaceutics

2014 Small interfering RNA (siRNA)-based therapies have great promise in the treatment of a number of prevalent pulmonary disorders including lung cancer, asthma and cystic fibrosis. However, progress in this area has been hindered due to the lack of carriers that can efficiently deliver siRNA to lung epithelial cells, and also due to challenges in developing oral inhalation (OI) formulations for the regional administration of siRNA and their carriers to the lungs.

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