Dr. Tim Morey is professor and chair of the Department of Anesthesiology in the College of Medicine. His research interests include measuring medication adherence using exhaled breath, employing exhaled propofol concentrations to understand anesthetic depth, alternative formulations for propofol, unique locations for pulse oximetry in patients with low perfusion states and others. Some of this technology has been transferred for development and commercialization to Xhale, a faculty start-up company headquartered in Gainesville.
Areas of Expertise (4)
Healthcare Affairs and Leadership
Case Report: Can Inhaled Adenosine Attenuate COVID-19?Respiratory Pharmacology
Bruce D. Spiess, et al.
This case report demonstrates a small repetition of the case series carried out in Italy wherein inhaled adenosine was administered to patients experiencing severe and worsening coronavirus disease-2019 (COVID-19). The two cases are important not only because they were the first of their type in the United States, but also because both patients were DNR/DNI and were therefore expected to die. Study repetition is vitally important in medicine.
The potential role of stress and sex steroids in heritable effects of sevofluraneBiology of Reproduction
Anatoly E. Martynyuk, et al.
Most surgical procedures require general anesthesia, which is a reversible deep sedation state lacking all perception. The induction of this state is possible because of complex molecular and neuronal network actions of general anesthetics (GAs) and other pharmacological agents. Laboratory and clinical studies indicate that the effects of GAs may not be completely reversible upon anesthesia withdrawal.
A Methyltransferase Inhibitor (Decitabine) Alleviates Intergenerational Effects of Paternal Neonatal Exposure to Anesthesia With SevofluraneAnesthesia and Analgesia
Ning Xu, et al.
Neonatal exposure to sevoflurane induces neurobehavioral and neuroendocrine abnormalities in exposed male rats (generation F0) and neurobehavioral, but not neuroendocrine, abnormalities in their male, but not female, offspring (generation F1). These effects of sevoflurane are accompanied by a hypermethylated neuron-specific K+-2Cl− (Kcc2) Cl− exporter gene in the F0 spermatozoa and the F1 male hypothalamus, while the gene’s expression is reduced in the F0 and F1 hypothalamus.