Victoria Watson
Director of Preclinical Education, Assistant Professor Michigan State University
- East Lansing MI
Victoria Watson develops large animal models of infectious pediatric gastrointestinal diseases
Biography
She is researching the role of the intestinal microbiome in health and disease in shelter kittens, and working to explain the interaction between members of the gut microbiome and protective mucus layer of the intestine.
Industry Expertise
Areas of Expertise
Education
University of South Carolina
B.S.
2003
University of Georgia
D.V.M
2009
North Carolina State University
Ph.D.
2017
Journal Articles
Robust coagulation activation and coagulopathy in mice with experimental acetaminophen-induced liver failure
Robust coagulation activation and coagulopathy in mice with experimental acetaminophen-induced liver failureDafna J. Groeneveld, Lauren G. Poole, Emma G. Bouck, Anthony Schulte, Zimu Wei, Kurt J. Williams, Victoria E. Watson, Ton Lisman, Alisa S. Wolberg, James P. Luyendyk
2023-09-01
Patients with acetaminophen (APAP)-induced acute liver failure (ALF) display both hyper- and hypocoagulable changes not necessarily recapitulated by standard hepatotoxic doses of APAP used in mice (eg, 300 mg/kg).
We sought to examine coagulation activation in vivo and plasma coagulation potential ex vivo in experimental settings of APAP-induced hepatotoxicity and repair (300-450 mg/kg) and APAP-induced ALF (600 mg/kg) in mice.
Soft tissue sarcomas in 2 zoo-housed Alaskan moose
Journal of Veterinary Diagnostic InvestigationBridget Walker, Ronan Eustace, Randall E. Junge, Tu Chun Hsu, and Victoria Watson
2022-06-07
Soft tissue sarcomas (STSs) are common well-described cutaneous neoplasms in many domestic species. Few cutaneous neoplasms have been reported in cervids, other than papilloma virus–induced benign cutaneous fibromas (BCFs). Two wild-caught Alaskan moose (Alces alces), housed at different North American zoos, were both presented with lameness and a mass.
Comparative Genomics of Atypical Enteropathogenic Escherichia coli from Kittens and Children Identifies Bacterial Factors Associated with Virulence in Kittens
ASM JournalsVictoria E. Watson, Tracy H. Hazen, David A. Rasko , Megan E. Jacob, Johanna R. Elfenbein, Stephen H. Stauffer, Jody L. Gookin
2021-02-16
Typical enteropathogenic Escherichia coli (tEPEC) is a leading cause of diarrhea and associated death in children worldwide. Atypical EPEC (aEPEC) lacks the plasmid encoding bundle-forming pili and is considered less virulent, but the molecular mechanism of virulence is poorly understood. We recently identified kittens as a host for aEPEC where intestinal epithelial colonization was associated with diarrheal disease and death.
