Biography
Wei-en Wang's work is focused on identifying and validating neuroimaging biomarkers that improve early diagnosis and predict disease progression in people with neurodegenerative diseases such as dementia and parkinsonism. She has developed imaging pipelines for various imaging modalities, including EEG, structural MRI, diffusion MRI, PET, and CT. The validation of innovative neuroimaging biomarkers has produced a series of publications in leading journals and presentations at international conferences on mild cognitive impairment, Alzheimer’s disease (AD), Lewy body disease, and chronic pain in human clinical populations.
Areas of Expertise (5)
Cortical Oscillations
Alzheimer's Disease and Related Dementias
Neuroscience and the Brain
Neuroscience
Structural and Functional Imaging
Articles (3)
Longitudinal Free-Water Changes in Dementia with Lewy Bodies
Movement DisordersShannon Y. Chiu, et. al
2024-03-13
Diffusion-weighted magnetic resonance imaging (dMRI) examines tissue microstructure integrity in vivo. Prior dementia with Lewy bodies (DLB) diffusion tensor imaging studies yielded mixed results.
Diffusion MRI relates to plasma Aβ42/40 in PET negative participants without dementia
Alzheimer's & DementiaJesse C. DeSimone, et. al
2024-03-05
Magnetic resonance imaging (MRI) biomarkers are needed for indexing early biological stages of Alzheimer's disease (AD), such as plasma amyloid-β (Aβ42/40) positivity in Aβ positron emission tomography (PET) negative individuals.
Plasma Alzheimer's biomarkers and brain amyloid in Hispanic and non-Hispanic older adults
Alzheimer's & DementiaBreton M. Asken, et. al
2023-09-06
We evaluated associations between plasma biomarkers commonly studied in Alzheimer's (p-tau181, GFAP, and NfL), clinical diagnosis (clinically normal, amnestic MCI, amnestic dementia, or non-amnestic MCI/dementia), and Aβ-PET in Hispanic and non-Hispanic older adults. Hispanics were predominantly of Cuban or South American ancestry.