Biography
Whitney L. Stoppel's expertise lies at the interface between transport in biological systems, biomolecular engineering natural biopolymer characterization, biomaterials development, and tissue engineering. The Stoppel Lab’s work investigates, alters, characterizes, and utilizes natural silk fibroin-based biopolymers derived from silk producing insects. Thus, they enjoy thinking about the interplay between polymer thermodynamics and reaction kinetics as they drive biopolymer secondary and tertiary structures and explore new sources for functional, dynamic biopolymers. The lab works to leverage these two completing forces within 3D material systems to develop responsive biomaterials for future applications in tissue engineering and disease treatment.
Areas of Expertise (9)
Nanomaterials
Surgical Materials
Silk Fibers
Silk Fibroin
Biomaterials
Silk
Tissue Engineering
Mechanics of Materials
Chemical Engineering
Articles (3)
Impact of crystalline domains on long-term stability and mechanical performance of anisotropic silk fibroin sponges
Journal of Biomedical Materials ResearchElizabeth L. Aikman, et. al
2024-03-12
Sponge-like materials made from regenerated silk fibroin biopolymers are a tunable and advantageous platform for in vitro engineered tissue culture and in vivo tissue regeneration. Anisotropic, three-dimensional (3D) silk fibroin sponge-like scaffolds can mimic the architecture of contractile muscle.
Harvesting Silk Fibers from Plodia interpunctella: Role of Environmental Rearing Conditions in Fiber Production and Properties
The Journal of Physical ChemistryBryce D. Shirk, et. al
2024-03-01
Silk fibers are produced by a wide variety of insects. The silkworm Bombyx mori (Bombyx) was domesticated because the physical properties of its silk fibers were amenable to the production of fine textiles. Subsequently, engineers have regenerated silk fibroin to form biomaterials. The monocular focus on Bombyx silk has underutilized the expanse of diverse silk proteins produced by more than 100,000 other arthropods.
Silk Fibroin Particles as Carriers in the Development of Hemoglobin-Based Oxygen Carriers
Advanced NanoBiomed ResearchMarisa O. Pacheco, et. al
2023-07-27
Oxygen therapeutics has a range of applications in transfusion medicine and disease treatment. Synthetic molecules and all-natural or semisynthetic hemoglobin-based oxygen carriers (HBOCs) have seen success as potential circulating oxygen carriers.
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