Yeongseon Jang
Assistant Professor University of Florida
- Gainesville FL
Yeongseon Jang specializes in designing and developing advanced supramolecular biomaterials through biomacromolecular self-assembly.
Biography
Areas of Expertise
Articles
Recombinant Fusion Proteins with Embedded Sensing Functions as Versatile Tools for Protocell Development
BiomacromoleculesBornita Deb, et. al
2024-12-02
Sensory capabilities are crucial for cells to interact with their environment. To mimic these functions in synthetic cells, we developed sensory globular protein vesicles (GPVs) made entirely of recombinant fusion proteins through self-assembly under aqueous conditions. GPVs demonstrate sensory functions via the formation of the FKBP-FRB ternary complex with the signaling molecule, rapamycin.
Architecting Multicompartmentalized, Giant Vesicles with Recombinant Fusion Proteins
BiomacromoleculesJooyong Shin, et. al
2024-08-06
We present a straightforward strategy for constructing giant, multicompartmentalized vesicles using recombinant fusion proteins. Our method leverages the self-assembly of globule-zipper-elastin-like polypeptide fusion protein complexes in aqueous conditions, eliminating the need for organic solvents and chemical conjugation.
Advancing Biomimetic Functions of Synthetic Cells through Compartmentalized Cell-Free Protein Synthesis
BiomacromoleculesJackson Powers & Yeongseon Jang
2023-11-14
Synthetic cells are artificial constructs that mimic the structures and functions of living cells. They are attractive for studying diverse biochemical processes and elucidating the origins of life. While creating a living synthetic cell remains a grand challenge, researchers have successfully synthesized hundreds of unique synthetic cell platforms.
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