Yeongseon Jang
Assistant Professor | University of Florida
Gainesville, FL, UNITED STATES
Yeongseon Jang specializes in designing and developing advanced supramolecular biomaterials through biomacromolecular self-assembly.
Biography
Yeongseon Jang's research is dedicated to advancing the field of supramolecular biomaterials, focusing on the engineering of both structural and functional properties to create innovative applications. She leverages the principles of soft matter assembly and recombinant technology to develop advanced biomaterials that meet specific needs. Through a deep understanding of interactions among soft materials such as polymers, proteins, and colloids, Jang aims to tailor the microscopic structure, physical properties, and functionality of our materials. Our techniques involve applying recombinant protein technology to design functional biological building blocks precisely. The result is a diverse array of supramolecular structures, including synthetic cells and antibacterial surfaces
Areas of Expertise (5)
Biomacromolecules
Biomolecular Engineering
Soft Matter
Self-Assembly
Biomimetics
Articles (3)
Recombinant Fusion Proteins with Embedded Sensing Functions as Versatile Tools for Protocell Development
BiomacromoleculesBornita Deb, et. al
2024-12-02
Sensory capabilities are crucial for cells to interact with their environment. To mimic these functions in synthetic cells, we developed sensory globular protein vesicles (GPVs) made entirely of recombinant fusion proteins through self-assembly under aqueous conditions. GPVs demonstrate sensory functions via the formation of the FKBP-FRB ternary complex with the signaling molecule, rapamycin.
Architecting Multicompartmentalized, Giant Vesicles with Recombinant Fusion Proteins
BiomacromoleculesJooyong Shin, et. al
2024-08-06
We present a straightforward strategy for constructing giant, multicompartmentalized vesicles using recombinant fusion proteins. Our method leverages the self-assembly of globule-zipper-elastin-like polypeptide fusion protein complexes in aqueous conditions, eliminating the need for organic solvents and chemical conjugation.
Advancing Biomimetic Functions of Synthetic Cells through Compartmentalized Cell-Free Protein Synthesis
BiomacromoleculesJackson Powers & Yeongseon Jang
2023-11-14
Synthetic cells are artificial constructs that mimic the structures and functions of living cells. They are attractive for studying diverse biochemical processes and elucidating the origins of life. While creating a living synthetic cell remains a grand challenge, researchers have successfully synthesized hundreds of unique synthetic cell platforms.
