The Canadian Technology Accelerator in Boston (CTA@Boston) is an award-winning immersion program that drives growth for small and medium sized Canadian companies. Operated by the Consulate General of Canada in Boston, the program has assisted over 77 Canadian companies since its founding in 2013 with its unique business acceleration services that help companies commercialize or scale their business in the US market.



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Joseph E. Italiano, Ph.D., faculty advisor

Reviewer of Peer-reviewed Journals including Blood, Platelets, PLoS ONE, Nature Communications, Canadian Medical Association Journal, Thrombosis and Haemostasis. 

Chairman, The XXII Congress of the International Society of Thrombosis and Haemostasis, 2009

Sequence-specific 2'-O-methoxyethyl antisense oligonucleotides activate human platelets through glycoprotein VI, triggering formation of platelet-leukocyte aggregates

Transfer to the clinic: refining forward programming of hPSCs to megakaryocytes for platelet production in bioreactors

In Vitro Functionality of hiPSC Derived PLT+: The Utility of Microfluidic Assays in Determining Potency

Jonathan excels at translating scientific advances into preclinical, and clinical stage programs. He is a problem solver and a disruptive innovator, with major contributions that include the production of extracellular vesicles for nonviral gene delivery, functional human platelets from stem cells, and the invention of bioreactor platforms to scale cell culture.

Before STRM.BIO, Jonathan was CEO & CSO of Platelet BioGenesis (now Stellular Bio), which he took from a startup concept to a Series A-1 company of over 40 employees. Jonathan was also a professor and lecturer at Harvard Medical School, where he guided dozens of students toward rewarding careers in medicine and biopharma. He is a frequent speaker at scientific conferences, entrepreneurship meetings, and thought leadership events around the world.

Jonathan earned his Ph.D. in biochemistry and molecular biology from the University of British Columbia and completed his postdoctoral research fellowship in hematology at Harvard Medical School.

Clinical Research

Life Sciences

Education

Stem Cell Biology

Human Cell Culture

Biomimetic Fluid Processing

Molecular Biology

Biochemistry

Board Participation

Western Blotting

Genetics

STRM.BIO

Personal Website

Google Scholar Citations

ResearchGate Citations

First in Human Episode #48 featuring Jonathan Thon

STRM.BIO Presents Preclinical Data on a Novel Bone Marrow/HSPC-Targeted, Megakaryocyte-Derived Extracellular Vesicle Delivery Platform for In Vivo Gene Therapy at the Cell & Gene Meeting on the Mesa

STRM.BIO Receives Extension of Grant to Advance In Vivo Gene Therapy Delivery Platform

Asked and Answered: Jonathan Thon Talks about Bringing Gene Therapy to Life

Systems and methods for biomimetic fluid processing

System and method for a biomimetic fluid processing

System and method for biomimetic fluid processing

Founder & CEO

Jonathan Thon is a serial biotech entrepreneur & recognized leader in human cell culture. He excels at translating scientific advances into clinically relevant programs, having made major contributions to the production of functional human platelets from stem cells & the invention of bioreactor platforms to scale cell culture. Jonathan currently serves as Founder & CEO of STRM.BIO, a pre-clinical, VC-backed biotechnology company that is leveraging extracellular vesicles (EVs) to deliver gene therapies in vivo. Before STRM.BIO, Jonathan founded & served as CEO / CSO of PlateletBio where he helped develop next-generation allogeneic cell therapies for the treatment of human diseases. He was also a Professor at Harvard Medical School, where he combined novel concepts in bone marrow physiology with cutting-edge technical advances in tissue engineering to develop safer and scalable therapies to hematological diseases. Jonathan takes great pride in having helped guide dozens of students toward rewarding careers in medicine & biopharma, and is a sought-after speaker for keynote addresses, presentations, panels and media appearances. Jonathan holds a Ph.D. in Biochemistry & Molecular Biology from the University of British Columbia & completed his postdoctoral research fellowship in Hematology at Harvard Medical School.

Learn More @ https://strm.bio
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