Featured Post from Augusta University

Augusta experts are making huge steps and providing new insight on coinfections, viral spread and COVID

Nov 16, 2021

2 min

Ravindra Kolhe, PhD


With mask wearing and social distancing on the decline and the cold and flu season upon us, researchers have developed a viral panel that enables the simultaneous testing for SARS-CoV-2 along with numerous common respiratory viruses, that tells us whether other viruses also are at play in patients hard hit by COVID.



This new genetic epidemiology tool that provides detailed genetic information about the viruses present when packaged with a molecular immunology model called Nextstrain also enables researchers to assess the novel viral variants that are circulating in a state or nation and patterns for their spread with the goal of helping predict and mitigate future outbreaks, says Dr. Ravindra Kolhe, director of the Georgia Esoteric and Molecular Laboratory, or GEM Lab, at the Medical College of Georgia at Augusta University.


Deficits in SARS-CoV-2 monitoring and keeping tabs on other co-circulating respiratory viruses have been public health challenges during the pandemic, Kolhe and his colleagues report in the journal Viruses.


Coinfection is a reality, Kolhe says with these respiratory viruses that we unwittingly transmit through the air when we cough, sneeze, even talk, particularly when we are in close quarters for long periods like hospitals, nursing homes, schools and potentially even our workplace.


Another reality is that coinfections can have the compounding effect of worsening symptoms and outcomes, much as we have all heard that co-morbid conditions like diabetes and hypertension can do, he says.



Particularly when patients are not doing well, looking for other respiratory viruses with the new panel could help provide insight on why and possibly new directions on how to help, he says. The more expansive panel is more expensive than straight COVID testing, which will remain the frontline test in this pandemic, Kolhe predicts.

While the cold and flu season were essentially a wash last year because of COVID precautions like mask wearing — in fact the coinfection rate in the group they studied was under 1% — he and others are concerned the cold and flu season now upon us will be very different even with vaccination initiatives for both COVID and the flu.




We’ve attached the full article – and it is well worth reading given the timing of flu season and another potential wave of COVID emerging globally.


This is a fascinating topic and if you are a journalist covering the latest advancements in the effort to contain and eradicate COVID-19 – then let our leading experts help with your coverage and questions.


Ravindra Kolhe is a Molecular and Genetic Pathologist, involved in identifying and validating cutting-edge platforms for diagnostic medicine. He’s also the Director of the Georgia Esoteric & Molecular Laboratory at Augusta University. If you are looking to arrange an interview with Dr. Kolhe – simply click on his icon now to find a time to talk today.


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Ravindra Kolhe, PhD

Ravindra Kolhe, PhD

Director, Georgia Esoteric & Molecular Laboratory at Augusta University

Ravindra Kolhe is a Molecular and Genetic Pathologist, involved in identifying and validating cutting-edge platforms for diagnostic medicine

Pathology InformaticsGenetic PathologyMolecular PathologySurgical Pathology

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5 min

AU expert talks Hurricane Helene’s impact on the supply chain

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You can’t anticipate everything, but we learned a lot from COVID and then the Baltimore bridge collapse and the supply chain disruptions those caused.” Franza said North Carolina is a case study in disruption to the supply chain at three different points: the source, manufacturing and transportation. “When we think about supply chain disruptions, people don’t typically think about it affecting the physical supply, but rather the transportation and logistics,” said Franza. “This one’s a little trickier because you have one industry affected by the supply of raw materials, another affected by the manufacturing of supplies and so many more will be affected by transportation problems.” Problems in manufacturing One industry that has been heavily impacted by the storm is the medical field, particularly the manufacturing of IV fluid bags. Baxter International, one of the largest producers of IV fluid bags in the country, has a manufacturing plant located in Marion, North Carolina. According to the American Hospital Association, the Marion plant produces 1.5 million IV bags per day, which equates to 60% of the country’s supply. “There are two big questions affecting the supply chain for those IV fluid bags,” said Franza. “If you lose a manufacturing facility, like the one in Marion, does another facility or a competitor have the ability to add capacity, even if it’s just a short term? The other piece of it is, even if they have the capacity, do they have the raw material inputs? So it’s a ripple effect.” In the wake of the storm, Baxter announced its other manufacturing facilities would increase their capacity. Thanks to its new Mount Carmel Mega Distribution Center located in Mississippi, the company feels confident it will be able to meet the needs of hospitals across the country. Baxter plans to increase allocation levels for direct customers from 40% to 60% and for distributors from 10% to 60%. They are also increasing allocations for designated children’s hospitals by 100%. Problems at the source Just outside the town of Spruce Pine, a town of less than 2,200 people located in the Blue Ridge Mountains, are two mines that produce an estimated 80% to 90% of the world’s most pure quartz. The quartz found in those mines is used in the manufacturing of semiconductors for microchips for everything from smartphones to cars to medical devices and more. The two companies that manage those two mines, Sibelco and The Quartz Corp, shut down operations on Sept. 26 ahead of the storm. As recovery efforts continue in the region, there remains more uncertainty as the full scope of the damage continues to be realized, and there is no certain timeline for when things will get started again. “The issue with natural resources like quartz is, unless you’ve come up with some method of producing an artificial version of it, you can’t really make it somewhere else,” said Franza. “Since there isn’t currently an alternative, it then becomes a question of is the mine accessible or how long until it is accessible and people can get back to regular operations?” Problems with transportation In Western North Carolina, entire roads along with buildings and other structures were wiped out as streams and rivers surged and mudslides occurred. On top of getting the mine back up and running, there is also the problem of getting the raw quartz where it needs to go. “Once you are able to access the ability of the mine to get back online, you then have the problem of whether the raw material can get where it needs to go to be processed,” said Franza. “A big problem in western North Carolina is entire roads are gone, and it’s not a simple repave. On top of that, Interstate 40 is estimated to be shut down until sometime next year, so transportation in that area is going to be extremely difficult for quite a while.” The good news is that quartz and the microchips that it is used in are not perishable items, and some chip manufacturers may have several weeks’ worth of quartz supply built up to be able to continue production. But an extended shutdown will likely mean even more chip shortages, similar to the global chip shortage that began in 2020 and lasted through 2023 due to the COVID-19 pandemic and the tightened restrictions in the countries that manufacture those chips. The loss of roads is not the only source of recent transportation problems, as immediately following the during the storm there was a three-day disruption in imports at 36 ports, including shutting 14 down stretching from Maine to Texas, as 45,000 dockworkers went on strike over pay. While that disruption could have caused serious issues, particularly for the upcoming holiday season, Franza said many companies have learned from previous disruptions, and most of the goods needed for Cyber Monday, Black Friday and preparing for the holiday season were already in the country. “I have heard that somewhere between 80% to 90% of the items for the holidays are already here, so the dock workers’ strike would not have been as much of an issue for the holidays, but there would definitely have been things you’d run out of.” Franza said the biggest problem during situations such as this is misinformation. “One of the biggest problems is most people are uninformed,” Ranza said. “Look at the toilet paper shortage at the beginning of COVID. If all of a sudden people rush to buy everything up and hoard it all, you can’t meet that demand so it causes even more problems. People need to be better informed because rumors start and then more problems are caused.” But Franza reiterated that companies have learned from past events, and that planning has made the supply chain stronger. “I think we’re better than we were four years ago because each of these crises builds our toolbox on how to plan for and deal with disruptions. It has built resiliency.”

2 min

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A new study by Lance Hunter, PhD, professor of social science in Augusta University’s Pamplin College of Arts, Humanities, and Social Sciences, reveals a direct link between voluntary involvement in civil social groups and a lower risk of suicide. In the study, published in Cross-Cultural Research, Hunter looked at data gathered from 2000 to 2019 from 156 countries with varying levels of development from Africa, Asia, Australia, Europe, North America and South America and found that participation in civil society groups, both political and non-political, may produce positive social and psychological benefits that are associated with lower suicide rates. September is National Suicide Prevention Month, during which mental health advocates, prevention organizations and other community groups promote suicide prevention awareness. “The greater the voluntary participation in civil society groups within the country, the lower the suicide rates are for that country,” said Hunter. “Voluntary civil society participation is a great way for people to connect with other individuals with similar interests and possibly find meaning and purpose to some degree. That in turn decreases feelings of social isolation, which can decrease the likelihood of suicidality or suicide.” Based on the research, he noted that social isolation is a major factor in suicide ideation and attempted suicide but it’s not the only factor. “It is important to note there are many psychological, biological, social and mental health factors that can contribute to suicide risk. Civil society participation and social isolation are just two factors among many that can affect suicidality,” said Hunter. Meredith Rausch, PhD, associate professor in the College of Education and Human Development’s Department of Research, Counseling and Curriculum, said research shows ideation and deaths by suicide in the United States tend to rise between February and April and again in August and September. “I have found the change in seasons often leads to people feeling overwhelmed when it comes to thinking about enduring another season,” said Rausch. “While the advent of spring or autumn may seem enjoyable or hopeful to some people, others find it to represent an entirely new season and the idea of experiencing that is exhausting.” Rausch also notes it’s important to note how these times of the year also coincide with the academic year, causing an increase in bullying, frustration with academics or other negative experiences for school-aged children. According to a 2023 study by the World Health Organization, more than 700,000 people worldwide die each year by suicide, and suicide is the fourth-leading cause of death among people 15 to 29 years old. Interested in learning more - let us help. Lance Hunter, PhD, is available to speak with media about this important topic - simply click on his icon to arrange an interview today.

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