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Gene Editing Institute’s Amanda Hewes Selected as a 2023 Outstanding Delaware Woman in STEM by Million Women Mentors

May 22, 2023

2 min

Amanda Hewes, MS, education program manager at ChristianaCare’s Gene Editing Institute, has been named one of the 2023 Outstanding Delaware Women in STEM by Million Women Mentors, an international movement dedicated to encouraging girls and women to pursue careers in science, technology, engineering and math (STEM).


Hewes’ selection spotlights her dedication to engaging young people in the science of gene editing by introducing the Gene Editing Institute’s CRISPR in a BoxTM educational toolkit into classrooms across Delaware and her commitment to bridging disparities in STEM education.


“I’m overjoyed to be honored among so many amazing women in this state,” Hewes said. “It’s humbling to be considered and to stand alongside them. All of these women foster and lead dynamic communities of young women that inspire me every day. I hope that I can do the same by making young women in this state feel empowered through the work that I do.”



Hewes joined ChristianaCare’s Gene Editing Institute in 2017 with a focus on expanding its CRISPR gene editing system in a cell-free environment. She was first author in a publication in Nature that established the highly innovative “gene editing on a chip” protocol that allowed CRISPR to edit DNA outside of the cell for the first time. This methodology enables researchers to take fragments of DNA extracted from human cells, place them in a test tube and precisely engineer multiple changes to the genetic code.


This gene editing system eventually led to the creation of the CRISPR in a Box™ toolkit. This innovative educational resource provides a way for students to learn about this exciting frontier of science through a hands-on exercise in which they use CRISPR gene editing to disrupt a synthetic gene within a plasmid. The simplicity of this experiment allowed for the reaction to be developed into a remarkable teaching tool that can be brought into most school laboratories containing basic laboratory equipment.


Once CRISPR in a Box™ was developed, Hewes recognized the potential it could have for high school and college students. She took on a new role as education program manager and expanded the Gene Editing 360™ platform, which is the Gene Editing Institute’s suite of educational tools for engaging students and the public.


“Amanda has set us on a tremendous path toward providing more educational opportunities for Delaware students,” said Eric Kmiec, Ph.D., director of ChristianaCare’s Gene Editing Institute. “She’s inspired young women in multiple states and has created so much of this program with her own ingenuity and passion.”


Hewes was honored alongside 10 other women by Gov. John Carney, Lt. Gov. Bethany Hall-Long and others at the Delaware State House with the signing of a proclamation to declare March 24, 2023, as “Delaware Women and Girls in STEM Day.”

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‘You Can Do and Be Anything Coming From an HBCU’

A late July dinner was the finale to her second internship with ChristianaCare for Tania Paden. Her eight weeks at Christiana Hospital had left her feeling more confident in herself and excited to continue exploring direct patient care as she prepares to head back to Delaware State University in the fall. “I learned how to be more comfortable with direct patient care and communicate with the patients,” Paden said. “My favorite thing would have to be going to tour the different units and getting shadowing experiences throughout the hospital.” Paden is one of 10 Future of Health Scholarship Program recipients at ChristianaCare. Graduates from Delaware high schools attending Historically Black Colleges and Universities (HBCUs) were each awarded a $12,500 annual scholarship and a paid summer internship in 2021 each year until they graduate. The program, a partnership between ChristianaCare and the HBCU Week Foundation, is designed to help support HBCU students as they pursue degrees in health care. Teachable moments and big opportunities Paden’s enthusiasm is shared by Natalie Torres, director of Inclusion & Diversity at ChristianaCare, who oversees the scholarship program. “This experience is so much more than offering the scholarship funding,” Torres said. “It’s the time, it’s those quiet moments in-between meetings and their experiences where the teachable moments really take place. “When they come to us, we really want to lock into their lived experiences, and not only make sure they can thrive at ChristianaCare, but in life.” With these scholarships and other community-based endeavors, ChristianaCare continues to work to build a diverse workforce and represent its communities. Forbes recently listed ChristianaCare as one of America’s Best Employers for Diversity for the fourth year in a row. Although she is a young intern herself, Aniyah Barnett, a rising biochemistry junior at Hampton University, jumped at the chance to help make new caregivers feel comfortable at ChristianaCare. She played a key role welcoming medical and dental residents to campus. “My favorite project was probably the new resident orientation,” Barnett said. “I spent time getting all the new residents together, making sure they have all the information they need, and getting to meet them!” A pathway to medicine For Ashley Christopher, Esq., founder and CEO of HBCU Week Foundation, these scholarships mean a lot. Ten years ago, Christopher had a stroke that left her feeling scared and alone as she lay in hospital. Her cardiologist, a Black woman, was the only one who made her feel heard, she told the students during their summer-end dinner. With IT experiences gained at ChristianaCare, Future of Health scholar Solomon Devard is thinking about continuing on that path to become a system administrator for a big corporation. “She was the only one who made me feel safe, secure and seen during a time where I was questioning life as I knew it,” Christopher said. “You can do and be anything coming from an HBCU. This scholarship gives students who want to go to HBCUs a pathway to the field of medicine for more people who look like me to tend to the care of patients.” The HBCU Week Foundation creates opportunities through coaching and scholarships for students who want to attend HBCUs. To support these efforts, ChristianaCare committed $500,000 to providing financial and networking support, and hands-on experiences for HBCU students. “These students are energized, they’re talented, and I’m so excited for the next step,” Christopher said. “I just feel so happy to be a part of that process.”

2 min

Center for Heart & Vascular Health Recognized for Continued Excellence with American College of Cardiology HeartCARE Center Designation

For the fifth consecutive year, ChristianaCare’s Center for Heart & Vascular Health has earned the premier recognition from The American College of Cardiology (ACC) – the HeartCARE Center National Distinction of Excellence award – for its commitment to comprehensive, high quality cardiovascular care. ChristianaCare was the first hospital system in Delaware and one of only a handful in the U.S. to attain this recognition when it was first awarded in 2020 from the ACC, a nonprofit medical association representing more than 50,000 cardiovascular specialists. “We are proud to be a regional leader for cardiovascular care with the most advanced medical, surgical and minimally invasive specialty care, technology and research,” said Kirk Garratt, M.D., medical director of ChristianaCare’s Center for Heart & Vascular Health. “Congratulations to our entire team and all who collaborate seamlessly to deliver care 24/7. As a result, those living in Delaware and neighboring states can receive the highest quality cardiovascular care from the Center for Heart & Vascular Health.” Hospitals that have earned an ACC HeartCARE Center designation have met a set of criteria, including participating in at least two ACC accreditation services programs, national cardiovascular data registries and targeted quality improvement campaigns designed to close gaps in guideline-based care. In addition to being a current recipient of the HeartCARE Center designation, ChristianaCare participates in the ACC’s chest pain MI with PCI (heart attack with angioplasty) and resuscitation accreditation, cath lab accreditation and the Society of Thoracic Surgeon database. “ChristianaCare has demonstrated its commitment to providing the community with excellent heart care,” said Deepak L. Bhatt, M.D., MPH, FACC, chair of the ACC accreditation management board. “ACC accreditation services is proud to award the Center for Heart & Vascular Health with the HeartCARE Center designation.” Hospitals receiving the HeartCARE Center designation have demonstrated their commitment to consistent, high-quality cardiovascular care through comprehensive process improvement, disease and procedure-specific accreditation, professional excellence and community engagement. ChristianaCare has proven to be a forward-thinking institution with goals to advance the cause of sustainable quality improvement. The Center for Heart & Vascular Health is among the largest, most capable regional heart centers on the East Coast. It is among the few centers in the region that integrates cardiac surgery, vascular surgery, vascular interventional radiology, cardiology and interventional nephrology in a single location. Its expert clinical staff performed nearly 200,000 patient procedures last year.

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