Dr Antonio Fratini

Senior Lecturer, Mechanical, Biomedical & Design Engineering Aston University

  • Birmingham

Dr Fratini's research is focussed on understanding how biomedical engineering can help to improve quality of life and clinical outcomes.

Contact

Aston University

View more experts managed by Aston University

View all Experts

Spotlight

2 min

Aston University researcher takes on leadership role within biomedical engineering

Dr Antonio Fratini is the new chair of the Institute of Mechanical Engineers Biomedical Engineering Division It is one of the largest group of professional biomedical engineers in the UK The specialism merges professional engineering with medical knowledge of the human body, such as artificial limbs and robotic surgery. An Aston University researcher has been given a leading role within the biomedical engineering sector. Dr Antonio Fratini CEng MIMechE has been elected as the new chair of the Biomedical Engineering Division (BmED) of the Institution of Mechanical Engineers (IMechE), one of the largest groups of professional biomedical engineers in the UK. The IMechE has around 115,000 members in 140 countries and has been active since 1847. Biomedical engineering, also known as medical engineering or bioengineering, is the integration of engineering with medical knowledge to help tackle clinical problems and improve healthcare outcomes. Dr Fratini previously served as chair of the Birmingham centre of the division for five years and as vice-chair of the division for one year. His research includes responsible use of AI, 3D segmentation and anatomical modelling to improve surgical training and planning, motor functions and balance rehabilitation. He leads Aston University’s Engineering for Health Research Centre within the College of Engineering and Physical Sciences and has vast experience in the design, development and testing of new medical devices. Currently he is the University’s principal investigator for the West Midlands Health Tech Innovation Accelerator and he has a growing reputation in the UK and internationally within the biomedical engineering profession. He said: “Biomedical engineering is continuously evolving and our graduates will create the future of health tech and med tech for more effective, sustainable, responsible and personalised healthcare. “I am very honoured of this appointment. This three-year post will be a great opportunity to further develop the biomedical engineering profession worldwide and to show Aston University’s commitment to an inclusive, entrepreneurial and transformational impact within the field.” Professor Helen Meese, outgoing chair of the division, said: “I am delighted to see Antonio take on the chair’s position. He has, over the years, contributed significantly to the growth of the Birmingham regional centre and has actively supported me throughout my tenure as chair. I know how passionate he is about our profession and will undoubtedly continue to drive the division forward over the next three years.” Dr Frattini was presented with his new title on 20 June at the IMECHE HQ at 1 Birdcage Walk, London during the Institution’s technology strategy board meeting. For media inquiries in relation to this release, contact Nicola Jones, Press and Communications Manager, on (+44) 7825 342091 or email: n.jones6@aston.ac.uk

Dr Antonio Fratini

2 min

Aston University scientists find mechanical stimulation could be used to prevent falls and strengthen muscles – research

Researchers find mechanical stimulation could be used to help improve balance control The findings provide new information on whole-body vibration applications Paves the way for research on the interaction between the central nervous system and peripheral muscles. Mechanical vibrations could help improve our muscles and our balance control, according to research at Aston University. Researchers in the College of Engineering and Physical Sciences have examined the effect of stimulation on muscle spindles which ‘speak’ to the central nervous system to help keep us upright and walk straight. Their results provide new perspectives on whole-body vibration applications, paving the way for future research on the interaction between the central nervous system and the peripheral muscles. The research could in future be applied to improve balance in older people and help reduce falls, this could be applied through either wearable devices or with a daily session of stimulation. Hip fractures alone account for 1.8 million hospital bed days and £1.1 billion in hospital costs every year, excluding the high cost of social care. Another potential benefit of the research is that this type of stimulation could be applied to athletes to decrease their muscle reaction times. The goal of the study was to find out if mechanical vibrations can improve the way our bodies process and react to small body oscillations. Seventeen young male and female adult volunteers aged between 20 and 28 years old stood individually on platforms, similar to vibrating plates found in gyms, which caused leg muscle contractions. Calf muscles were targeted as the muscles whose action contribute the most to maintaining a stable upright posture. The researchers stimulated their calves with a frequency of 30Hz and recorded four one-minute trials of undisturbed balance to take a baseline measure and compared the readings to measurements taken after the stimulation. After conducting the experiment, they found that their balance seemed to have improved. The research, Sensorimotor recalibration of postural control strategies occurs after whole body vibration, was led by Dr Antonio Fratini, senior lecturer in mechanical, biomedical & design engineering, and PhD student Isotta Rigoni, and has been published in Scientific Reports – Nature. Dr Fratini said: “We’re excited by our results as they could have a beneficial effect on the health and quality of life of a large number of people. “Our results indicate that whole body vibration challenges balance at first, triggering a bigger effort to control the upright stance and shifting muscle modulation toward supraspinal control, resulting in a recalibration of muscle recruitment. The neuromuscular system seems to recover from such disruption and regain control over a longer time interval.” “Indeed, while muscle recruitment and cortical effort appear unaltered over the long term, the balance seems not only restored but also improved, besides the still clearly affected calf muscles.” For more information about our research or studying in the College of Engineering and Physical Sciences please visit our website.

Dr Antonio Fratini

Social

Biography

Dr Fratini is a Biomedical Engineer with strong interests in the areas of medical biomedical data processing (imaging, segmentation, modelling), and instrumentation (biosensing and diagnostics).

His work has contributed to the design and development of cutting-edge medical devices and improvement of current medical treatments. His research has contributed to the outputs of leading national and international academic institutions and small-to-medium enterprises (SME).

Areas of Expertise

Biomedical Engineering
Medical Instrumentation
Physiological Data Processing
Proprioceptive Stimulation
Wearable Medical Devices

Education

Aston University

PGcPP

Higher Education

2015

Università degli Studi di Napoli Federico II

PhD

2008

Università degli Studi di Napoli Federico II

Hons

Electronic Engineering

2005

Affiliations

  • Leader of the Biomedical Engineering Programmes
  • Member of the AUEA Board of Directors

Articles

Characterisation of the transient mechanical response and the electromyographical activation of lower leg muscles in whole body vibration training

Scientific Reports

2022

The aim of this study is to characterise the transient mechanical response and the neuromuscular activation of lower limb muscles in subjects undergoing Whole Body Vibration (WBV) at different frequencies while holding two static postures, with focus on muscles involved in shaping postural responses. Twenty-five participants underwent WBV at 15, 20, 25 and 30 Hz while in hack squat or on fore feet. Surface electromyography and soft tissue accelerations were collected from Gastrocnemius Lateralis (GL), Soleus (SOL) and Tibialis Anterior (TA) muscles. Estimated displacement at muscle bellies revealed a pattern never highlighted before that differed across frequencies and postures (p 

View more

Cortical pathways during Postural Control: new insights from functional EEG source connectivity

IEEE Transactions on Neural Systems and Rehabilitation Engineering

2022

Postural control is a complex feedback system that relies on vast array of sensory inputs in order to maintain a stable upright stance. The brain cortex plays a crucial role in the processing of this information and in the elaboration of a successful adaptive strategy to external stimulation preventing loss of balance and falls. In the present work, the participants postural control system was challenged by disrupting the upright stance via a mechanical skeletal muscle vibration applied to the calves. The EEG source connectivity method was used to investigate the cortical response to the external stimulation and highlight the brain network primarily involved in high-level coordination of the postural control system. The cortical network reconfiguration was assessed during two experimental conditions of eyes open and eyes closed and the network flexibility (i.e. its dynamic reconfiguration over time) was correlated with the sample entropy of the stabilogram sway. The results highlight two different cortical strategies in the alpha band: the predominance of frontal lobe connections during open eyes and the strengthening of temporal-parietal network connections in the absence of visual cues. Furthermore, a high correlation emerges between the flexibility in the regions surrounding the right temporo-parietal junction and the sample entropy of the CoP sway, suggesting their centrality in the postural control system. These results open the possibility to employ network-based flexibility metrics as markers of a healthy postural control system, with implications in the diagnosis and treatment of postural impairing diseases.

View more

Toward a priori noise characterization for real-time edge-aware denoising in fluoroscopic devices

Biomedical Engineering Online

2021

Low-dose X-ray images have become increasingly popular in the last decades, due to the need to guarantee the lowest reasonable patient’s exposure. Dose reduction causes a substantial increase of quantum noise, which needs to be suitably suppressed. In particular, real-time denoising is required to support common interventional fluoroscopy procedures. The knowledge of noise statistics provides precious information that helps to improve denoising performances, thus making noise estimation a crucial task for effective denoising strategies. Noise statistics depend on different factors, but are mainly influenced by the X-ray tube settings, which may vary even within the same procedure. This complicates real-time denoising, because noise estimation should be repeated after any changes in tube settings, which would be hardly feasible in practice. This work investigates the feasibility of an a priori characterization of noise for a single fluoroscopic device, which would obviate the need for inferring noise statics prior to each new images acquisition. The noise estimation algorithm used in this study was tested in silico to assess its accuracy and reliability. Then, real sequences were acquired by imaging two different X-ray phantoms via a commercial fluoroscopic device at various X-ray tube settings. Finally, noise estimation was performed to assess the matching of noise statistics inferred from two different sequences, acquired independently in the same operating conditions.

View more

Powered by