E. Alison Holman

Professor of Nursing UC Irvine

  • Irvine CA

E. Alison Holman studies the early post-event predictors of co-morbid trauma-related mental and physical health problems.

Contact

UC Irvine

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Media

Biography

E. Alison Holman's research focuses on understanding the early post-event predictors of comorbid trauma-related mental and physical health problems. She seeks to identify predictors of, contributions of, and interactions between acute responses to trauma (biological, cognitive, emotional, social, environmental, behavioral) that increase vulnerability to trauma-related health problems, especially cardiovascular disease. Toward this end, Holman examines gene-environment interactions and the roles of several biological systems in acute/posttraumatic stress response: renin-angiotensin-aldosterone, endocannabinoid, and oxytocin systems as well as hypothalamic-pituitary-adrenal axis response. The ultimate goal is to identify targets for early interventions to prevent trauma-related morbidity and mortality.

Areas of Expertise

Physical health
Acute Stress
Acute Stress & Cardiovascular Disease
Psychological Trauma
Media Exposure

Education

U.C. Irvine

PhD

Health Psychology

1996

University of California, Santa Cruz

BA

Psychology

1989

San Francisco State University

BS

Nursing

1981

Affiliations

  • International Society for Traumatic Stress Studies
  • Association for Psychological Science
  • American Psychological Association, Divisions of Health Psychology and Trauma Psychology
  • California Association for Nurse Practitioners

Media Appearances

Dealing with psychological weight of economic uncertainty

KTVU  online

2025-04-08

Alison Holman, health psychologist at the Bill & Sue Gross School of Nursing at UC Irvine gives insight on mental health, dealing with economic uncertainty and the current political climate. “One of the more important things people can do in situations like this to not get stuck feeling they’re alone in dealing with this. To be able to find and stay connected with family, friends and people who are there to support you. Getting support from your groups is a really important step to deal with this stress,” said Holman.

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UTA study finds potential link between parental divorce and stroke later in life

The Dallas Morning News  online

2025-02-27

While there’s no question childhood trauma can leave lasting scars that contribute to poor health outcomes later in life, the study has limitations to bear in mind, said E. Alison Holman, a professor of nursing at the University of California, Irvine, who was not involved in the study. Holman’s research looks into how psychological trauma, especially early in life, impacts subsequent mental and physical health. … “It’s very possible that there’s a lot of stress in between that may have been the real trigger of the stroke.”

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Why communities only seem to come together during a crisis, according to science

Fast Company  online

2025-02-12

Another expert, Alison Holman, a professor at the UC Irvine School of Nursing … has extensive experience researching the effects of individual and collective traumas, including Southern California wildfires. Like USC’s [John] Brekke, she believes identity is a key factor that drives empathy and altruism during crisis moments. “What may be happening is that people identify, to some extent, with the people, the victims,” she says. “We have found in our work that identifying with victims is really something that helps to encourage people to engage in pro-social behavior.

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Research Grants

Genetic variation, stress, and functional outcomes after stroke rehabilitation

National Institute of Nursing Research

7/1/2015-6/30/2020

A national longitudinal study of community trauma exposure

National Science Foundation

1/1/2015-12/31/2017

RAPID: Responding to Terror of a Different Kind: A National Study of the Ebola Epidemic

National Science Foundation

12/1/14 - 11/30/15

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Articles

Reported Worst Life Events and Media Exposure to Terrorism in a Nationally Representative U.S. Sample

Journal of Traumatic Stress

Rebecca R. Thompson, E. Alison Holman, Roxane Cohen Silver

2020

Indirectly experienced negative life events are not considered Criterion A traumatic events per DSM‐5 posttraumatic stress disorder diagnostic criteria, yet individuals indirectly exposed to trauma via the media may report these events as peak traumatic experiences. We studied which events people considered to be the “worst” in their lifetimes to gain a better understanding of the types of events individuals consider to be distressing.

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The Novel Coronavirus (COVID-2019) Outbreak: Amplification of Public Health Consequences by Media Exposure

Health Psychology

Dana Rose Garfin, Roxane Cohen Silver, E. Alison Holman

2020

The 2019 novel coronavirus (COVID-2019) has led to a serious outbreak of often severe respiratory disease, which originated in China and has quickly become a global pandemic, with far-reaching consequences that are unprecedented in the modern era. As public health officials seek to contain the virus and mitigate the deleterious effects on worldwide population health, a related threat has emerged: global media exposure to the crisis.

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Associations between exposure to childhood bullying and abuse and adulthood outcomes in a representative national U.S. sample

Child Abuse & Neglect

Josiah A Sweeting, Dana Rose Garfin, E Alison Holman, Roxane Cohen Silver

2020

Negative childhood experiences are associated with poor health and psychosocial outcomes throughout one’s lifespan.

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