Jan D. Hirsch

Founding Dean, School of Pharmacy and Pharmaceutical Sciences UC Irvine

  • Irvine CA

Jan Hirsch's research interests are focused in the areas of pharmacoeconomics and outcomes research.

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Biography

Dr. Jan D. Hirsch is Founding Dean of the University of California Irvine School of Pharmacy and Pharmaceutical Sciences and also Professor of Clinical Pharmacy. She is a Distinguished Scholar and Fellow of the National Academies of Practice (NAP) in Pharmacy, and Distinguished Fellow of the Get the Medications Right (GTMRx) Institute, and joined UC Irvine in January of 2019.
Previously she was Professor of Clinical Pharmacy and Chair of the Division of Clinical Pharmacy at the Skaggs School of Pharmacy and Pharmaceutical Sciences, at the University of California, San Diego. She was also Executive Director of an outreach program of the school providing medication therapy management services in the community. She received her B.S. in Pharmacy and M.S. and Ph.D. degrees in Pharmacy Administration from the University of South Carolina, College of Pharmacy. Prior to returning to academia, she spent 14 years in the pharmaceutical and managed care industries where she was responsible for establishing and managing outcomes research departments for two pharmaceutical companies (Glaxo Group Research in Greenford (UK) and Allergan (US)) and a pharmacy benefit management company (Prescription Solutions (US)).

Dr. Hirsch's research interests are focused in the areas of pharmacoeconomics and outcomes research. Specifically, i) assessing the full value (economic, clinical and humanistic) of pharmacy services and pharmaceuticals and ii) integrating patient reported outcomes (PRO's) [e.g. Health Related Quality of Life (HRQOL)] into pharmaceutical and medical practice to improve patient management.

She has served as PI or Co-PI for many studies evaluating the clinical, economic and humanistic outcomes for patients receiving novel pharmacy services for diabetes, hypertension, mental health, and HIV/AIDS. This research has been recognized by state and federal agencies, professional pharmacy organizations and the interdisciplinary National Academies of Practice. Dr. Hirsch has also been the PI for studies creating and/or validating four HRQOL instruments [Functional Living Index Emesis (FLIE), Ocular Surface Disease Index (OSDI), Gout Impact Scale (GIS), Heart Transplant Treatment Burden Questionnaire (HTBQ)] and a method for measuring medication regimen complexity (MRCI). Each of these has been an important contribution to clinical practice and research as evidenced by their uptake by other researchers and inclusion in more than 100 clinical trials.

Areas of Expertise

Comprehensive Medication Management (CMM)
Medication Therapy Management
Clinical Pharmacy
Pharmacoeconomics
Drug Development
Gout Impact Scale
Pharmaeutical Services
Disease-specific Instruments
Health Related Quality of Life

Accomplishments

Distinguished Scholar and Fellow National Academies of Practice in Pharmacy (NAP)

2018

Distinguished Scholar and Fellows have an exemplary career of ten years or more, and are committed to interprofessional practice and accessible, affordable healthcare for all. Fellows are judged by distinguished peers to have made significant and ongoing contributions in their profession.

Distinguished Scholar and Fellows have made notable academic achievements such as significant and enduring educational and/or research contribution to practice.

Distinguished Fellow of Get the Medications Right Institute (GTMRx)

2019

The GTMRx Distinguished Fellows program celebrates the exceptional contributions of those advancing our ability to enhance life by ensuring appropriate and personalized use of medication and gene therapies.

Distinguished Fellows drive innovation, policy, and work alongside like-minded national leaders to advance evidence, best practices, and ideas to accelerate the transformation to a team-based, person-centered approach to comprehensive medication management.

Excellence in Teaching Award

2004

UCSD

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Education

University of South Carolina

MS

Pharmacy Administration

1982

University of South Carolina

Ph.D.

Pharmacy Administration

1986

University of South Carolina

BS

Pharmacy

1980

Affiliations

  • American Pharmaceutical Association (APhA)
  • Academy of Managed Care Pharmacy (AMCP)
  • American Association of Colleges of Pharmacy (AACP)
  • California Pharmacists Association (CPhA)
  • National Academies of Practice (NAP)
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Languages

  • English

Media Appearances

Should Kids Take Ozempic, Wegovy? The Idea Has Some Experts Worried

HealthDay  online

2023-08-30

“Our major concern is the unbalance and inappropriate reductions in calorie or energy intake associated with these weight-loss drugs,” said Dr. Dan Cooper, a professor of pediatrics at UCI School of Medicine. … Co-author Jan Hirsch, [founding] dean of the UCI School of Pharmacy and Pharmaceutical Sciences [and professor of clinical pharmacy], said, … "These drugs administered without proper supervision could cause a minefield of health and emotional problems for children as they age." … “News about GLP-1RA agonists has infiltrated social media outlets …. “ said Dr. Emma Cooper, a resident in the Department of Psychiatry and Human Behavior at UCI School of Medicine.

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Pharmacists in Nontraditional Roles Are Not Included in Bureau of Labor Statistics Count of Working Pharmacists

Pharmacy Times  online

2023-02-14

Jan Hirsch, BS, PhD, FNAP, UCI founding dean and professor of clinical pharmacy in the School of Pharmacy and Pharmaceutical Sciences write, “Collective action among stakeholders is needed to first produce an inclusive count of pharmacists giving accurate visibility to the magnitude of pharmacists in non-traditional roles, and second to re-examine projections for pharmacist jobs using an inclusive view for all positions that value pharmacy training and expertise. These are essential steps to allow an accurate perception of pharmacy as a career path and meaningful workforce planning that ensures the profession will be prepared with an adequately trained workforce to meet health care needs of the future.”

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UC Irvine welcomes inaugural class of pharmacy school with white coat ceremony

Daily Pilot  online

2021-09-24

“It’s not just students but our faculty too,” said Jan Hirsch, founding dean of the school, in a call Thursday.

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Preferred Pronouns

Preferred Pronouns

She, Her, Hers

Research Focus

Gout disease-specific quality of life and the association with gout characteristics

2010-07-01

Assess the association of gout characteristics with health-related quality of life (HRQoL) using a new gout-specific HRQoL instrument, the Gout Impact Scale (GIS).

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Evaluation of an Instrument Assessing Influence of Gout on Health-Related Quality of Life

2008-12-01

The study was conducted to evaluate the reliability and validity of an instrument assessing the influence of gout (acute and chronic) on health-related quality of life (HRQOL).

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Research Grants

Assessment of Stakeholder Perspectives of the Clinical Utility of Pharmacogenomics in Solid Organ Transplantation

Skaggs Scholar Program

2017-07-01

The focus of the study is to assess stakeholder perspectives regarding the clinical utility of pharmacogenomic (PGx) testing following kidney, liver, and heart transplantation. The study conducted by individual semi-structured interviews and focus groups with kidney, liver, and heart transplantation patients and providers.

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Reducing Hospital Utilization (Readmissions and ED) Community Pharmacist Medication Reconciliation Program

United Healthcare

2016-09-30

A longitudinal study seeking to reduce hospital reutilization (readmission and ER utilization) by adding community pharmacists to the care team. The objective of the study is to conduct and evaluate implementation of a community pharmacy based transitions of care program (PharmD_TOC)for high-risk post-discharge patients.

The study runs from September 2016 to January 2021.

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Multidimensional Efficacy of Canukinumab vs. Triamcinolone for Gouty Arthritis Treatment

Novartis Pharmaceuticals

2012-09-03

Canakinumab (CAN), a selective, fully human, anti-IL-1β monoclonal antibody, may be a potential therapeutic option for treating acute gout attacks and delaying new attacks in these patients (pts). Efficacy and safety of canakinumab was previously demonstrated in two 12-week, multicenter, double-blind, double dummy, active controlled trials (β-RELIEVED [N=228]; β-RELIEVED II [N=226]).1 Health-related quality of life was also measured in these studies, but not all patients completed each questionnaire. Therefore, a composite health outcomes response endpoint was developed to better interpret each patient’s overall response to treatment.

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Articles

National survey of physicians’ perspectives on pharmacogenetic testing in solid organ transplantation. Clinical Transplantation.

PubMed

KM Deininger, SM Tsunoda, JD Hirsch, HD Anderson, YM Lee, CK McIlvennan, RL Page, JN Tran, CL Aquilante

2020
https://media-speakerfile-pre.s3.amazonaws.com/documents/e63a2ee611561a5c7d8d0122405801fe1602693325.pdf

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Local pharmacies can reduce the dual risks of COVID19 and influenza this fall. Now is the time to prepare.

The Hill

JH Watanabe and JD Hirsch

2020
https://media-speakerfile-pre.s3.amazonaws.com/documents/e63a2ee611561a5c7d8d0122405801fe1602693325.pdf

PaCIR: A Tool to Enhance Pharmacist Patient Care Intervention Reporting

Journal of the American Pharmacists Association

PG Clay, AL Burns, BJ Isetts, JD Hirsch, MA Kliethermes, LG Planas

2019
https://media-speakerfile-pre.s3.amazonaws.com/documents/e63a2ee611561a5c7d8d0122405801fe1602693325.pdf

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