Aston University teams up with eye care provider to reduce NHS patient backlog
Aston University and Eye Docs Ltd enter Knowledge Transfer Partnership to establish new shared-care regimes for eye care patients The new model will help patients access Eye Docs surgeons It will help reduce NHS waiting lists, outpatient clinic backlogs, improve patient care and deliver profits of over £8.8 million Aston University has teamed up with private ophthalmic services clinic, Eye Docs, to undertake a 32-month Knowledge Transfer Partnership (KTP), to help clear NHS surgery waiting-lists and outpatient backlogs.
In the West Midlands, average NHS waiting times have increased to over 12 months due to the impact of the Covid-19 pandemic, with waiting list contracts ranging from 100 to 1,500 patients.
A cross-disciplinary team from Aston University’s School of Optometry and Aston Business School will work with West Midlands-based company Eye Docs to create a ‘shared-care’ model as part of the KTP.
A KTP is a three-way collaboration between a business, an academic partner and a highly qualified researcher, known as a KTP associate.
The working model will encompass clinical optometry and management science expertise to identify which patient appointments could be undertaken in community practices and which need to be seen by Eye Docs surgeons. It is hoped this way of working will also help reduce pressure on the NHS creating a more efficient and cost-effective model that will benefit all stakeholders from patients to clinicians.
The Aston University team will be led by Professor Shehzad Naroo, professor of optometry, who brings expertise in leading multidisciplinary groups and managing projects that improve eye care service delivery. Professor Naroo has a long history of working with private clinics to improve delivery of eye care, increasing efficiency and widening the role of private clinics to support the NHS.
He will be supported by Professor Prasanta Dey, professor in operations and information management, whose research interests are in project management, service operations management, supply chain management and applications of multi-criteria decision making in industry.
Completing the team will be Dr Yang Zhao, senior lecturer in operations and information management, whose research interests are in business model design, digital business models, platform business models, digital innovation, digital healthcare and digitalisation in aging societies.
Professor Shehzad Naroo, professor of optometry at Aston University, said: “It is a privilege to be involved in this KTP, which will enable Eye Docs to increase patient numbers to fully utilise theatre capacity by receiving more surgical referrals from local optometrists. “We’re thrilled to be able to help Eye Docs to offer community-based services to patients and help to reduce the burden on the NHS.” Professor Shah, consultant ophthalmic surgeon and co-owner of Eye Docs, said: “This partnership will allow us to adopt the latest research and expertise from a world-leading academic institute to develop new patient pathways and shared-care regimes, enabling us to grow our business and profitability, develop new services and improve patient care. “Working with a multidisciplinary team of clinical and business experts from Aston University will help us to achieve the aims of this project.”
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3 min
Aston University research to support SMEs and mid-sized companies to be ‘future ready’
‘Future readiness’ is defined as a set of capabilities and orientations that enable companies to thrive in the future Researchers say SMEs and mid-sized companies’ leadership should focus on bridging their resilience gap and exploiting their high level of agility The report found circular economy can combat environment and social impact without sacrificing economic performance. A new report from Aston University has highlighted opportunities for small and medium sized enterprises (SMEs) and mid-sized companies to develop strategies and pathways to increase their future readiness.
The report defines future readiness as “a set of capabilities and orientations that enable companies to thrive in the future”. For SMEs and mid-sized businesses to be future-ready, they must be successful on the three pillars of long-term growth, societal impact and adaptive capacity.
Experts say they must be able to generate lasting financial strength driven by innovative business models, products and/or services, to affect society positively in line with environmental, social and governance (ESG) goals and to develop high levels of resilience and agility, which enables them to bounce back in difficult times and to identify and seize opportunities as they emerge, creating disruption in business models for the future.
The report aims to support leadership teams and the wider ecosystem in understanding how they can help increase the capacity for smaller companies to thrive and positively impact the economy and environment, as well as aid the recovery from the pandemic.
Experts also say that circular economy adoption, where the ‘make, use and throw away’ supply chain is converted to ‘take, make, distribute, use and recycle’, in SMEs and mid-sized companies creates a win-win situation for every supply chain stakeholder through sustainability measures to achieve economic, environment and social performance.
The World Economic Forum will use the insights generated in this report to further support SMEs and mid-sized companies in their future readiness journey. This will be done through the creation of additional resources, including the continuous development of the Forum’s self-assessment and benchmarking tool on future readiness, the creation of a platform for informal peer-to-peer learning between companies and meet ups with key experts.
Prasanta Kumar Dey, professor in operations and information management at Aston Business School and lead author of the report, said:
“The post-COVID-19 era is significantly more challenging than most people had initially hoped. Heightened geopolitical tensions, the energy crisis, supply chain disruptions, hyperinflation and extreme weather events are just a few of the difficulties that will make the next decade a demanding one. “SMEs and mid-sized companies’ leadership should try to focus on bridging their resilience gap and exploiting their high level of agility, afforded by their smaller size, as a competitive advantage. “Future readiness capability building should not be developed as ad-hoc initiatives but should be embedded into key corporate strategies and decision-making processes, ideally from the beginning, so that it becomes part of the fundamental building blocks of the company. “While smaller companies can go a long way in building their future readiness, it is important to recognise the direct and important impact that their wider policy environment has on their ability to thrive. It is therefore crucial for policymakers, investors and other stakeholders to do what is in their capabilities to contribute to building the future readiness of this segment of the economy. “One of the high-impact areas of intervention at the system levels revolves around digital trade and includes implementing targeted measures to harmonize and drive trade data interoperability across borders and supply chains. This would greatly contribute to making it easier for smaller companies to trade internationally.” You can find out more about the report findings here.
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2 min
SMEs are likely to achieve higher environmental performance through circular economy adoption – new research
The research looked into the means for achieving higher sustainability performance through circular economy adoption The project was led by Professor Prasanta Dey and Professor Pawan Budhwar from Aston Business School Data was gathered from around 100 SMEs from Greece, France, Spain and the UK. New findings from an Aston University-led study have found Small and Medium Sized Enterprises (SMEs) are likely to achieve higher environmental performance through circular economy (CE) adoption.
CE is a systemic approach to economic development designed to benefit businesses, society, and the environment. In contrast to the 'take-make-waste' linear model, a circular economy is regenerative by design and aims to gradually decouple growth from the consumption of finite resources.
The project was led by Professor Prasanta Dey and Professor Pawan Budhwar from Aston Business School along with Soumyadeb Chowdhury (Toulouse Business School), Krishnendu Saha (Birmingham City University), Debashree De (University of Essex) and Chrysovalantis Malesios (Agricultural University of Athens).
Data was gathered from around 100 SMEs from each of the four selected countries – Greece, France, Spain and the UK using a survey to study the current state of CE adoption, and subsequently, focus groups were organised which involved SMEs owners and managers, policymakers, SMEs' customers and suppliers, in each country to derive means for improving sustainability performance.
The study reveals that SMEs in all the participating countries are likely to achieve higher environmental performance through CE adoption. SMEs in France were likely to achieve higher overall sustainability performance than other participating countries.
It also found products, processes and facilities design is likely to help SMEs most in all the participating countries to adopt CE, while their waste management all needed improvement.
Professor Budhwar, head of Aston Business School, said:
“Although from prior research there is evidence of SMEs achieving superior environmental performance by adopting CE, economic and social performances are not assured. This motivated us to undertake empirical research to reveal the means for achieving higher sustainability performance (economic, environmental, and social) through CE adoption”. “The findings of this research enable us to continue CE adoption not only in other European countries but also in India, Thailand, Vietnam and Kenya”. Professor Dey, a professor in operations and information management at Aston Business School, said:
“SMEs in the EU countries are likely to have sustainable design practices aligned with the CE philosophy. On the contrary, SMEs in the participating countries are likely to have worst recover function. “This implies that customers' pressure works for SMEs to adopt CE principles as design function in most of the SMEs' businesses is governed by SMEs' customers. Whereas effective recover function depends on SMEs' self-motivation and policymakers’ pressure.” “CE adoption needs a structured approach of analysing current state of CE through analysing correlation of organisational value functions with sustainability performance, identifying issues and challenges, and suggesting means for improvement across value functions.” You can read the full report here.
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Biography
Dr. Prasanta Kumar Dey is a professor in Operations and Information Management at Aston Business School, Aston University, UK. Prior to joining Aston University in 2004, he worked for 4 and half years with the University of West Indies in Barbados as a Director of a graduate project management program and 13 years in Indian Oil Corporation Limited, India as a project executive. He has a bachelor in mechanical engineering from Jadavpur University, Kolkata, India, Master’s in Industrial engineering and management from Asian Institute of Technology, Bangkok, Thailand, and Doctoral degree in Production engineering from Jadavpur University. He specializes in low carbon supply chain management and project management. He has extensively published in the international refereed journals (e.g. IEEE Transactions in Engineering Management, International Journal of Production and Operations Management, International Journal of Production Economics, European Journal of Operation Research, Supply Chain Management International Journal, Energy). He is a visiting professor of Rouen Business School and Toulouse Business School in France, University of Deusto in Spain, University of South Australia, University of Bamberg in Germany, and University of Vienna in Austria. He is the founder co-editor of the International Journal of energy Sector Management. He has published more than one hundred research papers in the leading international refereed journals. He has accomplished several research projects funded by Ford Foundation, Research Council, UK, British Council, and West Midlands Manufacturing Advisory Services. His industry clients include Jaguar Land Rover, Rolls Royce, JCB, L’Oreal, NHS, Britons Carpet, Cemex, Indian Oil Corporation Limited, Kuwait National Petroleum Company and Unocal.
Areas of Expertise
Environmental Management
Total Quality Management
Service Operations Management
Project Management
Supply Chain Management
Education
Jadavpur University
PhD
Production Engineering
1997
Asian Institute of Technology
MS
Industrial Engineering
1992
Jadavpur University
BS
Mechanical Engineering
1985
Affiliations
International Journal of Energy Sector Management : Chief Editor
Journal of Advances in Management Research : Editorial Review Board Member
EX-527 Prevents the Progression of High-Fat Diet-Induced Hepatic Steatosis and Fibrosis by Upregulating SIRT4 in Zucker Rats
Cells
Amit Kundu, Prasanta Dey, Jae Hyeon Park, In Su Kim, Seung Jun Kwack, Hyung Sik Kim
2020-04-29
Sirtuin (SIRT) is known to prevent nonalcoholic fatty liver disease (NAFLD); however, the role of SIRT4 in the progression of hepatic fibrosis remains unknown. We hypothesize that EX-527, a selective SIRT1 inhibitor, can inhibit the progression of high-fat diet (HFD)-induced hepatic fibrosis. We found that SIRT4 expression in the liver of NAFLD patients is significantly lower than that in normal subjects. In this study, EX-527 (5 µg/kg), administered to HFD rats twice a week for ten weeks, reduced the serum levels of triglyceride (TG), total cholesterol, alanine aminotransferase (ALT), and aspartate aminotransferase (AST) and attenuated hepatic fibrosis evidenced by Masson’s trichrome and hepatic fat by oil red-O staining. EX-527 upregulated SIRT2, SIRT3, and SIRT4 expression in the liver of HFD fed rats but downregulated transforming growth factor-β1 (TGF-β1) and α-smooth muscle actin (α-SMA) expression. It decreased proinflammatory cytokine production and hydroxyproline levels in the serum and SMAD4 expression and restored apoptotic protein (Bcl-2, Bax, and cleaved caspase-3) expression. These data propose a critical role for the SIRT4/SMAD4 axis in hepatic fibrogenesis. SIRT4 upregulation has the potential to counter HFD-induced lipid accumulation, inflammation, and fibrogenesis. We demonstrate that EX-527 is a promising candidate in inhibiting the progression of HFD-induced liver fibrosis.
Healthcare supply chain management: Application in the Maltese Healthcare System
Health Services Management Research
Sandra C Buttigieg, Frank Bezzina, Andrew Xuereb, Prasanta K Dey
2020-04-02
Hospital supply chains are complex systems ensuring flow of products/services to satisfy patients. The aim of this exploratory study is to improve the Maltese health care system’s efficiency using supply chain management principles in three hospital settings. The theoretical basis underlying the study is the supply chain decision-making framework.
The circular economy (CE) represents a major paradigm shift of moving from the concepts of linear to circular supply chains across multiple industries. Although some aspects of CE adoption within industrial supply chains have been researched extensively (particularly addressing challenges of design, implementation, and operations), the research that relates CE practices with sustainability performance to reveal the current state of CE practices within small and medium‐sized enterprises (SMEs) is scant. The aim of this research was to facilitate SMEs to achieve greater sustainability through CE implementation. This research addresses three research questions—How are CE fields of action related to sustainability performance? What are the issues, challenges, and opportunities of adopting CE in SMEs? And what key strategies, resources, and competences facilitate effective implementation of CE in SMEs? This study adopts a mixed method approach (qualitative and quantitative) using survey research, focus group, and case studies; 130 randomly selected SMEs within the Midlands of the United Kingdom have been surveyed, and the responses are analysed using statistical tools along with findings from focus groups and case studies. The study reveals that all CE fields of action (take , make , distribute , use , and recover ) of SMEs are correlated to economic performance, but only make and use are related to environmental and social performance. The study further derives strategies, resources, and competences for achieving sustainability across all the CE field of actions. Additionally, this research reveals the issues and challenges, strategies, resources, and competences required for implementing CE in SMEs.
Adverse health risk from prolonged consumption of formaldehyde-preserved carps in eastern region of Indian population
Environmental Science and Pollution Research
Amit Kundu, Prasanta Dey, Rammohan Bera, Ratul Sarkar, Boomin Kim, Sam Kacew, Byung Mu Lee, Sanmoy Karmakar & Hyung Sik Kim
2020-03-02
Presence of formaldehyde as a preservative in commonly available fishes (Labeo rohita, Catla catla, Anabas testudineus and Clarias gariepinus) has become a serious health concern in the public health of eastern region of India. Formaldehyde content was determined using high-performance liquid chromatography (HPLC). Results showed high formaldehyde content in frozen carp (19.66 and 23.3 mg/kg in Labeo rohita and Catla catla, respectively); however, the amount of formaldehyde was significantly reduced in boiled and fried fish (80 °C and 100 °C for 5 min) in mustard, coconut, and sesame oils. However, formaldehyde contents in non-carp fishes (Anabas testudineus and Clarias gariepinus) were almost negligible, compared to those in L. rohita and C. catla. In vivo toxicity studies showed a time-dependent increase in blood formaldehyde levels in rats after they were fed formaldehyde-contaminated fish (23.3 mg/kg) for 7 days. Histopathological analysis of the stomach of rats fed contaminated fish showed destruction and granulation of the protective mucus layer and detachment from the secretory layer. Taken together, our results indicated that continuous consumption of formaldehyde-contaminated carps commonly available in the eastern region of India may be associated with adverse health effects.
Protective effect of EX-527 against high-fat diet-induced diabetic nephropathy in Zucker rats
Toxicology and Applied Pharmacology
Amit Kundu, Sachan Richa, Prasanta Dey, Kyeong Seok Kim, Ji Yeon Son, Hae Ri Kim, Seok-Yong Lee, Byung-Hoon Lee, Kwang Youl Lee, Sam Kacew, Byung Mu Lee, Hyung Sik Kim
2020-03-01
High-fat diet (HFD)-induced obesity is implicated in diabetic nephropathy (DN). EX-527, a selective Sirtuin 1 (SIRT1) inhibitor, has multiple biological functions; however, its protective effect against DN is yet to be properly understood. This study was aimed to explore the protective effect of EX-527 against DN in HFD-induced diabetic Zucker (ZDF) rats. After 21 weeks of continually feeding HFD to the rats, the apparent characteristics of progressive DN were observed, which included an increase in kidney weight (~160%), hyperglycemia, oxidative stress, and inflammatory cytokines, and subsequent renal cell damage. However, the administration of EX-527 for 10 weeks significantly reduced the blood glucose concentration and kidney weight (~59%). Furthermore, EX-527 significantly reduced the serum concentration of transforming growth factor-β1 (49%), interleukin (IL)-1β (52%), and IL-6 in the HFD-fed rats. Overall, the antioxidant activities significantly increased, and oxidative damage to lipids or DNA was suppressed. Particularly, EX-527 significantly reduced blood urea nitrogen (81%), serum creatinine (71%), microalbumin (43%), and urinary excretion of protein-based biomarkers. Histopathological examination revealed expansion of the extracellular mesangial matrix and suppression of glomerulosclerosis following EX-527 administration. EX-527 downregulated the expression of α-SMA (~64%), TGF-β (25%), vimentin, α-tubulin, fibronectin, and collagen-1 in the kidneys of the HFD-fed rats. Additionally, EX-527 substantially reduced claudin-1 and SIRT1 expression, but increased the expression of SIRT3 in the kidneys of the HFD-fed rats. EX-527 also inhibited the growth factor receptors, including EGFR, PDGFR-β, and STAT3, which are responsible for the anti-fibrotic effect of SIRT-1. Therefore, the administration of EX-527 protects against HFD-induced DN.
