Rebecca Christofferson

Associate Professor Louisiana State University

  • Baton Rouge LA

Dr. Christofferson is an international expert on emerging zoonotic and mosquito-borne viruses.

Contact

Louisiana State University

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Biography

Rebecca Christofferson is a PhD-trained virologist and infectious disease epidemiology experienced in translating complex data into actionable insights. Her work spans laboratory and field-based research on vector-borne viruses, outbreak modeling and response, and translational outreach grounded in public health impact and global biosecurity.

Areas of Expertise

Neglected Tropical Diseases
Viruses
Epidemiology
Infectious Disases
Biosecurity
Diagnostics

Research Focus

Arbovirus Ecology & Epidemiology

Dr. Christofferson’s research focuses on arbovirus ecology and epidemiology, examining how environmental conditions and mosquito biology drive transmission of Zika, dengue, chikungunya, and West Nile viruses. She blends vector-competence experiments, field mosquito surveillance, and climate-based modeling to predict outbreak risk and guide Gulf Coast public-health and control strategies.

Accomplishments

Pereboom Alumni Association Professor of Excellence Ogden Honors College

2022-2025

2021 Worley Professor of Excellence

2021

Professorship awarded to one faculty annually at LSU for excellence in innovation and scholarship

Zoetis Research Award

2018

Excellent in research award for School of Veterinary Medicine

Education

Louisiana State University

Ph.D.

2011

Louisiana State University

MApSt

2005

Louisiana State University

B.S.

2002

Answers

What are the risks associated with the Chikungunya virus?
Rebecca Christofferson

Chikungunya is a virus that can lead to a variety of disease states. Most people will get a flu-like illness which may involve intense body aches. Some people will have persistent arthralgia - sometimes debilitating - that lasts for months or even years. There have been some cases of Guillian-Barré syndrome, which causes progressive paralysis. While temporary, this can be dangerous. Rarely, Chikungunya can lead to death.

Is chikungunya virus something we should be concerned about and paying attention to in the US?
Rebecca Christofferson

"The answer is not ‘no.’Chikungunya is transmitted by Aedes aegypti, which we have in South Florida, South Texas, Arizona, California… a little bit in Louisiana. Dengue virus is also transmitted by this mosquito species, so we can look at where we’ve had outbreaks of dengue to see where is most at-risk: Miami, South Texas, Southern California… But chikungunya also is transmitted by the Asian Tiger Mosquito – Aedes albopictus – of which we have a lot in more temperate areas like most of Louisiana, and up into New York. This is the mosquito with the black and white stripes on her legs and a stripe down what can be thought of as her ‘head.’ So in addition to where aegypti is, we have to worry about a larger swath of the US at-risk for chikungunya. There are so many factors that contribute to how at-risk a particular place is – the temperature, the environment, etc. In places where there is mosquito avoidance infrastructure, there will be less risk."

How can we prevent and control large-scale outbreaks of chikungunya virus as it spreads to new regions due expanding mosquito habitats?
Rebecca Christofferson

It depends on the context and location. If you’re talking about Louisiana, then we have to remember we have the infrastructure to protect us from outbreaks – screens on the windows, AC, robust spraying in most places. It’s always good to have additional education for both clinicians and the public to enhance their understanding of what chikungunya is and what kind of disease it presents. This strengthens our ability to prevent travel-associated cases and also detect outbreaks faster and respond with increased vector control or vaccine rollout. There are also two vaccines available for chikungunya. One is a live-attenuated vaccine indicated for 18+ years old (Ixchiq) and another for 12+ (VIMKUNYA), which is a virus-like particle vaccine. (That means it’s a protein that mimics the chikungunya virus but does not replicate.) Both have been shown to prevent infection, but vaccination should always be discussed with your physicians, and you need about 2 weeks before it’s fully efficacious. So if you’re traveling, take that into account. It’s important to educate the public on how to reduce mosquito contact through personal protection (bug spray, for example) and reducing standing water where the mosquitoes lay eggs. This is especially important in areas without the kinds of infrastructure that we have in place.

Media Appearances

America’s first severe case of bird flu confirmed in Louisiana

CNN  

2024-12-18

“The cases across the US are a constellation of spillovers,” said Dr. Rebecca Christofferson, a virologist at Louisiana State University’s School of Veterinary Medicine. Experts still don’t understand exactly how these spillovers are happening and the specific factors that increase a person’s risk.

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LSU Vet Professor weighs in on potential poultry vaccine for bird flu

KPLC  tv

2025-02-24

Rebecca Christofferson is an associate professor at the LSU School of Veterinary Medicine who specializes in infectious disease transmission.

“In 2023, France actually rolled out a bird flu vaccine for their duck industry and saw great success there,” Christofferson said.

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One bird flu case found in Louisiana out of 60 in the country this year

WBRZ-ABC  tv

2024-12-17

BATON ROUGE — The Louisiana Department of Health announced its first confirmed human case of bird flu. The person, who is from southwestern Louisiana and is currently in the hospital, is one of 60 cases from around the country as of December 2024.

Of the 60 confirmed virus cases in humans, none of them have involved human-to-human transmission.

"There are spillover risks, and that is what we are seeing right now, which is when a virus comes from an animal population into the human population," said Dr. Rebecca Christofferson from LSU's Veterinarian School.

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Articles

Exploring the transmission modalities of Bunyamwera virus

Experimental Biology and Medicine

2024

Bunyamwera virus (BUNV) (Bunyamwera orthobunyavirus) has been found in Sub-Saharan Africa and demonstrated recently as cocirculating with Rift Valley Fever Virus (RVFV). Little is known regarding the breadth of transmission modalities of Bunyamwera. Given its co-occurence with RVFV, we hypothesized the transmission system of BUNV shared similarities to the RVFV system including transmission by Ae. aegypti mosquitoes and environmentally mediated transmission through fomites and environmental contamination.

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Investigating the Effects of Microclimate on Arboviral Kinetics in Aedes aegypti

Pathogens

2024

Aedes aegypti are indoor-dwelling vectors of many arboviruses, including Zika (ZIKV) and chikungunya (CHIKV). The dynamics of these viruses within the mosquito are known to be temperature-dependent, and models that address risk and predictions of the transmission efficiency and patterns typically use meteorological temperature data. These data do not differentiate the temperatures experienced by mosquitoes in different microclimates, such as indoor vs. outdoor.

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Predicting severe COVID-19 using readily available admission indicators: SpO2/FiO2 ratio, comorbidity index, and gender

Experimental Biology and Medicine

2024

The focus of this study was to identify risk factors for severe and critical COVID-19, evaluate local respiratory immune responses to SARS-CoV-2 infection, and develop a prognostic tool for COVID-19 severity using accessible early indicators.

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