Featured Post from University of Florida

The health challenges astronauts Butch Wilmore and Suni Williams face after 9 months in space

Jan 5, 2026

4 min

Rachael Seidler
CaptionResizeWrap TextRemove


On June 5, 2024, astronauts Butch Wilmore and Suni Williams embarked on a brief mission to the International Space Station. But equipment failures turned what was supposed to be an eight-day trip into a grueling 9 month spaceflight.


This week, Wilmore and Williams finally returned to Earth. While their safe return is cause for celebration, the journey doesn’t end when astronauts touch down on Earth. They now face the significant task of recovering from the physical and psychological toll of long-duration spaceflight.


As part of the University of Florida’s ongoing research into astronaut health, Rachael Seidler, Ph.D., a leading expert in spaceflight-associated health changes, is studying the long-term effects of space travel on astronauts’ brains and bodies. Seidler’s research focuses on understanding how the central nervous system and brain structure adapt to the challenges of space travel, as well as how these changes affect performance, balance, and mobility once astronauts return to Earth.


“While the physical and psychological challenges astronauts face after returning from long-duration space missions are well-documented, the research we do at UF is helping us understand the intricacies of their recovery process,” said Seidler, deputy director of the Astraeus Space Institute at UF. “By following astronauts like Butch and Suni before, during, and after their missions, we can track how the human body responds to the extreme conditions of space.”


Behavioral and Brain Changes Post-Flight

Seidler’s research tracks astronauts’ physical and neurological recovery by observing them both during their missions and after they return.


"One of the most immediate challenges astronauts face when they return to Earth is mobility and balance. These issues often recover more quickly compared to others, but it takes time for astronauts to readjust to gravity,” Seidler said. "The balance, mobility, and walking difficulties astronauts experience during the first weeks back are typically resolved in a short period, but brain function and structure require longer recovery periods."


Seidler’s research indicates that astronauts’ brains exhibit compensation when they return to Earth following spaceflight. This compensation occurs through the recruitment of additional neural pathways in order to return to their preflight performance levels. However, the recovery of brain function is a gradual process. "This brain functional compensation is typically no longer observed within one to six months post-flight," Seidler said.


However, not all changes are reversible. "Brain structural changes, particularly related to fluid shifts in space, show little to no recovery even after six months to a year," Seidler said. Two significant structural changes include the brain physically sitting higher in the skull and the expansion of the brain’s ventricles — fluid-filled cavities in the brain — which can increase in volume by 25% or more. These changes are thought to result from the fluid shifts caused by microgravity, and they present long-term health considerations for astronauts.



Long-Term Health Effects: Understanding the Impact

As Wilmore and Williams embark on their recovery journey, the long-term impact of these changes becomes a critical focus for researchers like Seidler. "The long-term health impacts are crucial to understand because they could affect how astronauts recover and perform in their daily lives post-mission," she said.


Seidler’s team at UF is conducting a new study in which they are tracking astronauts for up to five years post-flight to better understand these long-term effects. "We’ve had astronauts in space for up to a year, and we know how to manage their physical health during those missions," Seidler said. "But the effects of space on the brain and body extend beyond the mission, and our work helps inform strategies to manage recovery."


Collaborating with NASA and Studying Spaceflight-Associated Neuro-Ocular Syndrome

Seidler's work is also part of a broader collaboration with NASA and other scientists to assess astronaut long-term health. The project is particularly focused on Spaceflight-Associated Neuro-Ocular Syndrome, which affects up to 70% of astronauts. This condition involves structural changes to the eye and optic nerve, leading to vision problems that may impact astronauts’ function.


"Neuropsychological assessments can help to measure astronauts’ brain health, while studies of the ocular system help identify potential vision issues that may arise during and after long-duration space missions," she said.


Simulating Space Conditions on Earth

In addition to studying astronauts on Earth and in space, Seidler’s team conducts experiments to simulate the effects of spaceflight on human physiology. The UF lab runs experiments in head-down tilt bed rest studies, which keep participants lying down for weeks to months at a time to simulate the lack of gravity. "This type of study helps us understand how fluid shifts in the body during space travel affect mobility, balance, and brain structure," Seidler explained. "In addition, other publications have reported that astronauts describe that vestibular galvanic stimulation feels similar to what they experience when they first arrive in space and when they return to Earth. We have equipment to induce these effects in the lab."


Looking Toward the Future

As space missions continue to grow longer and more complex, UF’s research is more important than ever. "We’re studying these issues now to ensure that future astronauts are prepared for the physical and cognitive challenges that await them in deep space," Seidler said.

Connect with:
Rachael Seidler

Rachael Seidler

Professor

Rachael Seidler researches the neural control of movement in health and disease, with a specific focus on motor learning.

SpaceParkinson'sCognitive AgeingNeuroscience and the BrainNeuroplasticity
Powered by

You might also like...

Check out some other posts from University of Florida

3 min

Surgery past 65? Brain health screening can aid recovery

Before surgery, your doctor will order evaluations to identify any health problems that may need to be addressed before the procedure. This typically includes medical histories, laboratory tests and checking blood pressure, heart rate and temperature. There’s one vital sign that is often not on the list, but is crucial for older adults: screening for mental and cognitive health. “There is an overwhelming amount of evidence that presurgical brain health predicts complications after surgery,” said Catherine Price, Ph.D., a professor in the University of Florida College of Public Health and Health Professions Department of Clinical and Health Psychology and the UF College of Medicine Department of Anesthesiology. “For example, individuals with weaknesses in memory and attention and people with neurodegenerative diseases, such as Parkinson’s, have higher rates of confusion and memory complications that affect their recovery from surgery.” Research by Price and others has shown that a patient’s cognitive, memory and mental health status before surgery is an excellent indicator of whether they will experience cognitive problems such as delirium, a common complications in older adults after surgery. Delirium, characterized by confusion, disorientation and impaired awareness, can lead to longer recovery times, increased dementia risk, higher mortality rates and health care costs. Price founded and directs the University of Florida Perioperative Cognitive Anesthesia Network, or PeCAN, a first-of-its-kind, multidisciplinary program that seeks to identify older adults who may be at risk of developing cognitive problems after surgery so that clinicians can intervene. In recent findings published in the journal Anesthesia and Analgesia, Price and her colleagues report on two years of PeCAN patient data. Of the thousands of patients over age 65 who received presurgical screening, 23% were found to have issues with their cognitive performance, yet only 2% of the patients screened had a previous note in their medical charts indicating they had a cognitive impairment. “It’s so important to know when an individual has cognitive complications because that changes their care path,” Price said. “From medication to monitoring, the patient’s care is more complex for the perioperative team and family.” For PeCAN patients identified as being at risk for postsurgery cognitive problems, Price and her team will share tailored recommendations with the patient’s care team before, during and after surgery. These may include more monitoring during anesthesia and medication adjustments, such as using medications for nausea and pain management less likely to contribute to delirium. The PeCAN team also might offer the surgical care team specific communication strategies. For example, health care providers should repeat information several times for patients who have trouble remembering new material and ask them to write it down. Recently published research by Price and colleagues found PeCAN patients reported the focus on brain health improved confidence in their surgical team and care plan. Health care systems are only starting to incorporate preoperative brain health teams like PeCAN. Until they are offered more frequently, Price offers a few steps anyone can take to help protect brain health, including a focus on reducing inflammation in the body prior to surgery. To help achieve this: Optimize nutrition. Reduce your intake of added sugars and refined carbohydrates, like white bread. Get good sleep. Improve sleep hygiene so you are well-rested. “Sleep is essential for the brain for a number of reasons,” Price said. Reduce alcohol intake to limit inflammation and dehydration. Pay attention to your medications. Follow your care team’s instructions. Enlist a family member or caregiver to help you keep tabs on what you’re taking, how much and how often. Practice techniques to limit anxiety, such as visualization and deep breathing. The box breathing method is an easy one to remember: Breathe in slowly for four seconds. Hold your breath for four seconds. Slowly exhale for four seconds. Wait four seconds before inhaling again.

3 min

Florida renters struggle with housing costs, new statewide report finds

Nearly 905,000 low-income renter households in Florida are struggling to afford their housing costs, according to the 2025 Statewide Rental Market Study, released by the University of Florida’s Shimberg Center for Housing Studies. Prepared for Florida Housing Finance Corporation, the report provides a comprehensive look at the state’s rental housing conditions and is used to guide funding decisions for Florida Housing’s multifamily programs, including the State Apartment Incentive Loan (SAIL) program. “Florida’s strong population growth has collided with limited housing supply, pushing rents beyond what many families can afford,” said Anne Ray, manager of the Florida Housing Data Clearinghouse at the Shimberg Center. “This report helps policymakers and housing providers target resources where the need is most acute — including communities that are experiencing the fastest growth and the greatest affordability gaps.” Key findings from the 2025 study include: A growing affordability gap: An estimated 904,635 renter households earning below 60% of their area median income (AMI) are cost burdened, paying more than 40% of their income toward rent. These households are spread across the state, with 64% in Florida's nine most populous counties, 33% in mid-sized counties and 3% in small, rural counties. Surging population and higher rent and housing costs: Between 2019 and 2023, Florida added more than 1 million households — nearly 195,000 of them renters — driven by in-migration from states like New York, Illinois and California. Despite the addition of more than 240,000 multifamily units, median rent soared nearly $500 per month, from $1,238 to $1,719. After years of growth, Florida's older renter population is holding steady: Renters age 55 and older represent 39% of cost burdened households, up from 29% in 2010 but similar to 2022 numbers. Most renters are working: 79% of renter households include at least one employed adult, compared to 67% of owner households. Most non-working renters are seniors or people with disabilities. Homelessness is on the rise: The report estimates 29,848 individuals and 44,234 families are without stable housing, up from 2022, as hurricanes and tight markets contribute to displacement. Assisted housing provides an alternative to high-cost private market rentals: Developments funded by Florida Housing, HUD, USDA and local housing finance authorities provide over 314,000 affordable rental units statewide. Future risks to affordable housing stock: More than 33,000 publicly assisted units may lose affordability protections by 2034 unless renewed. Evalu ating affordable housing in Florida “State- and federally-assisted rental housing developments are essential to providing stable, affordable homes for Florida’s workforce, seniors, and people with special needs,” Ray said. “Florida Housing Finance Corporation’s programs make up a significant portion of this housing, and our study helps ensure those resources are directed where they’re needed most. Preserving these developments — and expanding them — is critical to keeping pace with Florida’s growing population and maintaining affordability.” Since 2001, the Shimberg Center has produced the Rental Market Study every three years to inform strategic investments in affordable housing across Florida. The study evaluates needs across regions and among key populations including seniors, people with disabilities, farmworkers and others. The Rental Market Study and the Florida Housing Data Clearinghouse are part of a 25-year partnership between the Shimberg Center and Florida Housing Finance Corporation to support data-driven housing policy and planning.

3 min

Labubu success demonstrates the benefits of the ‘blind box’ business strategy

Labubu dolls have taken the world by storm. The viral collectable keychains that feature plush monster-like figurines, sold by the Chinese company Pop Mart, have been compared to other toys like Beanie Babies or the more recent Sonny Angels. Labubus come in a variety of colors and outfits, and they are sold in “blind boxes” — so customers never know which collectibles they will get when they buy them. The meteoric ascent of these toys raises the question: What exactly is the appeal of Labubus? According to Tianxin Zou, Ph.D., an assistant professor of marketing in the University of Florida Warrington College of Business, there are a few reasons behind Pop Mart’s success. “It’s a little bit like buying a lottery ticket,” Zou said about the blind box concept. “The uncertainty is giving another layer of enjoyment.” Zou compares the psychological experience of blind boxes to gambling, stating that some customers buy hundreds of boxes for the chance at winning big. Customers aren’t just buying the products; they’re buying the experience. Each Labubu release features 12 figurine designs, as well as a much rarer secret design, so customers are enticed by the possibility of getting that one rare doll. This can also come with monetary value, as Labubus have been resold for thousands of dollars on platforms like eBay. Recently, a first-generation Labubu toy sold for $150,000 in a Labubu-specific auction. The unboxing experience can also trigger social interaction. People often film themselves unboxing the products and posting the experiences online for millions to see, or they gather in person to open boxes with their friends. This brings people together, forming a sense of community and identity around Labubu ownership. “Unboxing the blind box together can become a joyful event,” Zou said. “It makes it so Labubu has a social value and can help form friendships.” The rarity of certain designs is also a key factor in the social aspect of Labubus. Within these communities, especially online, owning rare designs can become a form of social capital. This has contributed to the rise of “Lafufus,” or fake Labubu dolls sold by retailers separate from Pop Mart. The craze has become less about the item itself and more about what it represents socially. Even if a keychain is fake, it still shows that the owner is socially in the know. Pop Mart also aligns itself with well-known franchises, such as Star Wars and Marvel, for branded blind box designs. And celebrity interest has helped the popularity of Labubus skyrocket. The toy first gained momentum after it was seen on the bag of Lisa, a member of the K-pop group Blackpink. Since then, Labubus have been spotted on the bags and belt loops of public figures ranging from Rihanna to Tom Brady. Zou explains that this furthers the social impact of the toys, as people aim to replicate celebrities’ style. “This collaboration with celebrities gives Pop Mart synergy, which gives it this stronger social effect,” Zou said. While the success of Labubus may seem spontaneous, it is actually the result of highly strategic business strategies. However, other retailers are catching on, providing competition for Pop Mart as more companies enter the blind box game. The retailer also faces new challenges, with countries like China and Singapore creating regulations for the sale of blind boxes, especially to children. But for now, the monsters continue to dominate the market, giving the company time to formulate new strategies. And because the company’s strength lies in its research and planning, it likely will not be going into its next phase blind.

View all posts
Powered by