Featured Post from Aston University

Association between early childhood symptoms of common ear, nose and throat problems and autism – new research

Apr 25, 2023

3 min

Dr Amanda Hall



  • Researchers find an association between autistic traits and young children with ear, nose and throat problems
  • The study used data from the Children of the 90s study which found 177 children were identified with a probable diagnosis of autism – 139 boys and 38 girls
  • The study looked at data from over 10,000 children from birth to four years old.


Ear, nose and throat (ENT) problems, relating to the ears, hearing and the upper respiratory system, are more common in young children with a subsequent diagnosis of autism, or who have demonstrated high levels of autism traits - finds new research published in BMJ Open.


The study, which was led by researchers from the University of Bristol and Aston University, looked at data from over 10,000 young children from birth to four years old, who were part of the Bristol’s Children of the 90s study. The team investigated whether early ear and upper respiratory signs are associated with the development of autistic traits.


Previous studies have found increased prevalence of ENT and related hearing conditions in children with autism compared with typically developing children, but much of this research has been carried out using health records, which can be biased.


In the new study, researchers used data from Children of the 90s study, a general population cohort which recruited over 14,000 pregnant women from the Bristol area between 1991 and 1992 and has followed the lives of their offspring ever since.

Within Children of the 90s, 177 children were identified with a probable diagnosis of autism – 139 boys and 38 girls. Those with autism traits were defined as the 10% of the sample with the highest trait scores.


The team analysed responses to three questionnaires in which mothers recorded the frequency of nine different signs and symptoms relating to the ears, hearing problems and upper respiratory system when their child was aged 18 to 42 months. These included signs such as mouth breathing, snoring, pulling/poking of the ears, ears going red, worse hearing during a cold, ear discharge and rarely listening.


The results found that the frequency of these symptoms was associated with high scores on each of the autism traits: social communication, coherent speech, sociability and repetitive behaviours, plus those with a clinical diagnosis of autism. Pus or sticky mucus discharge from the ears was especially associated with autism (an increased risk of 3.29) and for impaired hearing during a cold (an increased risk of 2.18).


Dr Amanda Hall, senior lecturer in audiology, at Aston University, said: “Thanks to the data available from Children of the 90s, we were able to analyse results from a large number of children. We found that common ear and upper respiratory signs and symptoms appear to be more prevalent in those with a subsequent diagnosis of autism or demonstrated high levels of autism traits.

“However it is also important to note that these ENT symptoms are very common in childhood and most children who experience these signs and symptoms do not go on to be diagnosed with autism.

“For example, of the group of around 1,700 children who snored at age 30 months, most of those 1,660 children did not get a later diagnosis of autism. Our results suggest the need for increased awareness of possible ENT conditions.”


Connect with:
Dr Amanda Hall

Dr Amanda Hall

Lecturer, Audiology

Dr Hall's research focuses on the causes and impact of hearing loss in children, at both the individual and the population level.

AudiologyShared Decision MakingAudiology Health Services ResearchCauses and Impact of Childhood Hearing LossLongitudinal Cohort Studies

You might also like...

Check out some other posts from Aston University

3 min

Aston University researcher develops new optical technique that could revolutionise medical diagnostics

New light technique could revolutionise non-invasive medical diagnostics Orbital Angular Momentum could be harnessed to improve imaging and data transmission through biological tissues Could eventually have potential to make procedures such as surgery or biopsies unnecessary. An Aston University researcher has developed a new technique using light which could revolutionise non-invasive medical diagnostics and optical communication. The research showcases how a type of light called the Orbital Angular Momentum (OAM) can be harnessed to improve imaging and data transmission through skin and other biological tissues. A team led by Professor Igor Meglinski found that OAM light has unmatched sensitivity and accuracy that could result in making procedures such as surgery or biopsies unnecessary. In addition it could enable doctors to track the progression of diseases and plan appropriate treatment options. OAM is defined as a type of structured light beams, which are light fields which have a tailored spatial structure. Often referred to as vortex beams, they have previously been applied to a number of developments in different applications including astronomy, microscopy, imaging, metrology, sensing, and optical communications. Professor Meglinski in collaboration with researchers from the University of Oulu, Finland conducted the research which is detailed in the paper “Phase preservation of orbital angular momentum of light in multiple scattering environment” which is published in the Nature journal Light Science & Application. The paper has since been named as one of the year’s most exciting pieces of research by international optics and photonics membership organisation, Optica. The study reveals that OAM retains its phase characteristics even when passing through highly scattering media, unlike regular light signals. This means it can detect extremely small changes with an accuracy of up to 0.000001 on the refractive index, far surpassing the capabilities of many current diagnostic technologies. Professor Meglinski who is based at Aston Institute of Photonic Technologies said: “By showing that OAM light can travel through turbid or cloudy and scattering media, the study opens up new possibilities for advanced biomedical applications. “For example, this technology could lead to more accurate and non-invasive ways to monitor blood glucose levels, providing an easier and less painful method for people with diabetes.” The research team conducted a series of controlled experiments, transmitting OAM beams through media with varying levels of turbidity and refractive indices. They used advanced detection techniques, including interferometry and digital holography, to capture and analyse the light's behaviour. They found that the consistency between experimental results and theoretical models highlighted the ability of the OAM-based approach. The researchers believe that their study’s findings pave the way for a range of transformative applications. By adjusting the initial phase of OAM light, they believe that revolutionary advancements in fields such as secure optical communication systems and advanced biomedical imaging will be possible in the future. Professor Meglinski added: "The potential for precise, non-invasive transcutaneous glucose monitoring represents a significant leap forward in medical diagnostics. “My team’s methodological framework and experimental validations provide a comprehensive understanding of how OAM light interacts with complex scattering environments, reinforcing its potential as a versatile technology for future optical sensing and imaging challenges.” ENDS https://www.nature.com/articles/s41377-024-01562-7 Light: Science & Applications volume 13, Article number: 214 (2024) August 2024 https://doi.org/10.1038/s41377-024-01562-7 Authors: Igor Meglinski, Ivan Lopushenko, Anton Sdobnov & Alexander Bykov About Aston University For over a century, Aston University’s enduring purpose has been to make our world a better place through education, research and innovation, by enabling our students to succeed in work and life, and by supporting our communities to thrive economically, socially and culturally. Aston University’s history has been intertwined with the history of Birmingham, a remarkable city that once was the heartland of the Industrial Revolution and the manufacturing powerhouse of the world. Born out of the First Industrial Revolution, Aston University has a proud and distinct heritage dating back to our formation as the School of Metallurgy in 1875, the first UK College of Technology in 1951, gaining university status by Royal Charter in 1966, and becoming The Guardian University of the Year in 2020. Building on our outstanding past, we are now defining our place and role in the Fourth Industrial Revolution (and beyond) within a rapidly changing world. For media inquiries in relation to this release, contact Nicola Jones, Press and Communications Manager, on (+44) 7825 342091 or email: n.jones6@aston.ac.uk

2 min

Aston University researchers to explore using AI and fibre-optic networks to monitor natural hazards and infrastructures

Aston University is leading a new £5.5 million EU research project Will focus on converting fibre-optic cables into sensors to detect natural hazards Could identify earthquakes and tsunamis and assess civil infrastructure. Aston University is leading a new £5.5 million EU research project to explore converting existing telecommunication fibre-optic cables into sensors which can detect natural hazards, such as earthquakes and tsunamis, and assess the condition of civil infrastructure. The project is called ECSTATIC (Engineering Combined Sensing and Telecommunications Architectures for Tectonic and Infrastructure Characterisation) and is part of the Horizon Europe Research and Innovation Action (RIA), which aims to tackle global challenges and boost the continent’s industrial competitiveness. Converting telecom fibres into sensors requires new digital signal processing to overcome the limited data storage and processing capabilities of existing communication networks. To address this the project will use localised, high performance digital processing that will integrate artificial intelligence and machine learning. The researchers’ goal is to minimise algorithms’ complexity while providing extremely accurate real-time sensing of events and network condition. The new laser interrogation and signal processing technologies will be tested using existing fibre optic networks, including those underwater, in cities, and along railway infrastructure to assess their potential. Delivered by a consortium of 14 partners across seven countries, from academic and non-academic sectors, the research will start in February 2025 and will last three and a half years. The Europe-wide team will be led by Professor David Webb who is based in the Aston Institute of Photonic Technologies (AIPT). Professor Webb said: “There are more than five billion kilometres of installed data communications optical fibre cable, which provides an opportunity to create a globe-spanning network of fibre sensors, without laying any new fibres. “These traverse the seas and oceans - where conventional sensors are practically non-existent - and major infrastructures, offering the potential for smart structural health monitoring.” Professor Webb will be joined by fellow researchers Professor Sergei Turitsyn, Dr Haris Alexakis and Dr Pedro Freire. For media inquiries in relation to this release, contact Nicola Jones, Press and Communications Manager, on (+44) 7825 342091 or email: n.jones6@aston.ac.uk

3 min

EU-UK Trade Deal continues to stifle trade with 27% drop in exports since 2021

New report shows persistent stifling effects of the impact of the Trade and Cooperation Agreement on UK-EU trade relations Monthly data show a 27% drop in UK exports and a 32% reduction in imports to and from the EU between 2021 and 2023 Recommendations for policy interventions include to negotiate sector-specific deals, engage with individual EU countries, and work on reducing non-tariff barriers A comprehensive analysis by researchers at the Centre for Business Prosperity at Aston University reveals that negative impacts of the UK-EU Trade and Cooperation Agreement (TCA) have intensified over time. The new report, Unbound: UK Trade Post Brexit, also shows a 33% reduction in the variety of goods exported, with the agricultural, textiles, clothing and materials sectors most affected. To assess the impact of the UK-EU TCA, the authors analysed monthly import and export between the UK and the EU, from January 2017 to December 2023 and separated into pre- and post-January 2021 when the agreement came into force. The monthly data shows a 27% drop in UK exports and a 32% decline in imports from the EU. Lead author, Professor Jun Du of Aston University says: “The Trade and Cooperation Agreement introduced substantial barriers and there are ongoing and marked declines in the value and variety of UK exports and imports. Without urgent policy interventions, the UK’s economic position and place in the global market will continue to weaken.” The UK-EU TCA redefined trade and investment rules and market access between the UK and the EU. Since it came into force, the UK government has negotiated several trade agreements, but the EU remains the UK’s largest trade partner. Exports for most sectors have decreased since January 2021, although the impact is varied. Agrifood, textile and clothing and material-based manufacturing have been among the hardest hit, with substantial declines in both export value and the variety of products exported. At the same time, some sectors such as tobacco, railway and aircraft manufacturing have seen modest increases in varieties of products exported. On the import side, most sectors have shrunk in both value and variety, particularly agrifood products, optical, textile and material-based manufacturing. A few sectors, for example, ships and furniture, have demonstrated noticeable increases in import product variety. The large variations across different goods categories and EU trade partners underscore the uneven effects of Brexit and the TCA on UK-EU trade dynamics, highlighting the need to understand the nuances and come up with tailored strategies that address the unique challenges of each sector within the new regulatory environment. The researchers make recommendations, outlining how sector-specific negotiations, streamlining customs procedures with digital technologies and reducing regulatory divergence could mitigate some of the impacts. Dr Oleksandr Shepotylo, the report’s co-author says: “Our findings indicate a decoupling of the UK from key EU final goods markets, accompanied by a shift in UK supply chains toward geographically closer EU trading partners for exports and smaller countries for imports. “This shift raises concerns and underscores the urgent need for a strategic reconfiguration of UK supply chains to maintain competitiveness.” Professor Du continues: “The TCA has introduced considerable barriers to UK-EU trade, particularly through increased Non-tariff measures (NTMs). “Addressing these issues through targeted improvements to the TCA is crucial to ensuring that UK businesses remain competitive in the European market. A structured, multi-faceted approach is necessary.” To find out more about these findings, click here.

View all posts
Powered by