Featured Post from Aston University

Aston University receives £10m from Research England to establish the Aston Institute for Membrane Excellence

Jan 16, 2024

5 min

Roslyn BillPaul TophamDr Matthew DerryDr Alan GoddardAndrew Devitt
Image shows how tiny water channels control how water enters and exits cells through their membranes


  • The Aston Institute for Membrane Excellence (AIME) will be set up with a £10m grant from Research England
  • AIME will be led by Professor Roslyn Bill from Biosciences and Professor Paul Topham from Chemical Engineering and Applied Chemistry
  • The globally unique institute will use biomimetic polymer membranes for applications such as water purification and drug development


Aston University will establish the Aston Institute for Membrane Excellence (AIME), a globally unique, cross-disciplinary institute to develop novel biomimetic membranes, after receiving a major grant of £10m from Research England.


AIME will be led by Professor Roslyn Bill, from the School of Biosciences, with co-lead Professor Paul Topham from the department of Chemical Engineering and Applied Chemistry (CEAC).


Membranes, both biological and synthetic, are hugely important in many sectors. For example, the world’s top ten selling human medicines all target proteins in biological membranes, while synthetic polymer membranes are used in the US$100bn/year water purification industry. The team behind AIME believes that the full potential of membranes will only be realised by an interdisciplinary group spanning biology, physics and chemistry that can investigate membranes holistically.


Professor Bill, a European Research Council (ERC) Advanced grantee leads Aston Membrane Proteins and Lipids (AMPL) research centre of excellence that studies the structure and function of membrane proteins and associated lipids. Professor Topham leads Aston Polymer Research Group (APRG), which investigates the nanoscale behaviour of block copolymers (a type of polymer with a structure made of more than one type of polymer molecule) and polymer technologies for membranes. AMPL and APRG have already begun collaborative research and AIME will bring together the complementary expertise of both research clusters into one institute.


AIME will initially comprise the eight researchers from AMPL and APRG. Alongside the co-leads Professor Bill and Professor Topham, will be Dr Alan Goddard, Professor Andrew Devitt, Professor Corinne Spickett, Dr Alice Rothnie, Dr Matt Derry and Dr Alfred Fernandez. It plans to recruit three further academics, six tenure-track research fellows, three postdoctoral research assistants (PDRAs), six PhD students, a research technician and a business development manager. Importantly, AIME will work with many existing Aston University colleagues to build a comprehensive research community focused on all aspects of membrane science.


The new AIME team will focus on the development of bioinspired, highly selective polymer structures for applications in water purification and waste remediation, nanoparticles loaded with therapeutic molecules to treat disorders ranging from chronic wounds to neurological injuries, and the purification of individual membrane proteins with polymers to study them as drug targets.


The vision is for AIME to become a ‘one-stop shop’ for interdisciplinary, translational membrane research through its facilities access and expertise, ideally located in the heart of the country.


Professor Bill said:


“The creation of AIME is ground-breaking. Together with Aston’s investment, E3 funding will deliver a step-change in scale and the rate at which we can grow capacity. We will address intractable scientific challenges in health, disease, and biotechnology, combining our world-class expertise in polymer chemistry and membrane biology to study membranes holistically. The excellence of our science, alongside recent growth in collaborative successes means we have a unique opportunity to deliver AIME’s ambitious and inclusive vision.”


Professor Topham said:


“We are really excited by this fantastic opportunity to work more closely with our expert colleagues in Biosciences to create advanced technology to address real world problems. From our side, we are interested in molecular engineering, where we control the molecular structure of new materials to manipulate their properties to do the things that we want! Moreover, we are passionate about a fully sustainable future for our planet, and this investment will enable us to develop technological solutions in a sustainable or ‘green’ way.”


Professor Aleks Subic, Vice-Chancellor and Chief Executive of Aston University, says:


“Our new Aston Institute for Membrane Excellence (AIME) will be a regional, national, and international research leader in membrane science, driving game-changing research and innovation that will produce a pipeline of high-quality research outcomes leading to socioeconomic impact, develop future global research leaders, create advanced tech spinout companies and high value-added jobs for Birmingham and the West Midlands region. Its establishment aligns perfectly with our 2030 strategy that positions Aston University as a leading university of science, technology and enterprise.”


Steven Heales, Policy Manager (Innovation) at the West Midlands Combined Authority, said:


“WMCA is delighted to see Research England back the Aston Institute for Membrane Excellence. This will enable Aston University’s excellent academics and research community to work closely with businesses to make advances in membrane technology and applications.


“In 2023 the West Midlands Combined Authority agreed a Deeper Devolution Trailblazer Deal with Government, which included a new strategic innovation partnership with Government. Projects like AIME are exactly the kind of impact we expect this new partnership to generate, so watch this space.”


Lisa Smith, chief executive of Midlands Mindforge, the patient capital investment company formed by eight Midlands research-intensive universities including Aston University, said:


“This grant is an important vote of confidence in the Midlands scientific R&D ecosystem. AIME will play an important role in the future research of pioneering breakthroughs in membrane science and enable the world-leading research team at Aston University to develop solutions to real world problems. We look forward to closely working with the Institute and nurturing best-in-field research being undertaken at Aston out of the lab and into the wider society so it can make a positive impact”.


Rob Valentine, regional director of Bruntwood SciTech, the UK’s leading developer of city-wide innovation ecosystems and specialist environments and a strategic partner in Birmingham Innovation Quarter, said:


"As a proud supporter of the Aston Institute for Membrane Excellence (AIME), I am thrilled at the launch of this groundbreaking initiative. AIME exemplifies Aston University's commitment to advancing cutting-edge interdisciplinary research and further raises the profile of the region’s exemplary research capabilities and sector specialisms.


AIME's vision of becoming a 'one-stop shop' for translational membrane research, strategically located at the heart of the country, aligns perfectly with our strategy at Bruntwood SciTech. We are committed to working with partners, including Aston University, to develop a globally significant innovation district at the heart of the UK where the brightest minds and most inspiring spaces will foster tomorrow’s innovation.”


Membrane research at Aston University has also recently received two other grants. In November 2023, Professor Bill received £196,648 from the Biotechnology and Biological Sciences Research Council’s Pioneer Awards Scheme to understand how tiny membrane water channels in brain cells keep brains healthy. In December 2023, a team led by AIME team-member Dr Derry received £165,999 from the Engineering and Physical Sciences Research Council to develop biomimetic membranes for water purification.


For more information about AIME, visit the webpage.


Connect with:
Roslyn Bill

Roslyn Bill

Professor of Biotechnology

Professor Bill's research on water flow in the body has revealed how to develop drugs that prevent brain swelling after injury or disease.

Membrane ProteinsBrain SwellingWater BalanceHealthy AgeingBrain Injury
Paul Topham

Paul Topham

Head of School of Infrastructure and Sustainable Engineering

Professor Topham's research is focussed on sustainable polymer science; making new plastics of the future for a wide range of applications.

Polymer ScienceBlock CopolymersElectrospinningBiodegradable PolymersX-ray Scattering
Dr Matthew Derry

Dr Matthew Derry

Lecturer in Chemistry

Dr Derry conducts research on block copolymer self-assembly using small-angle X-ray scattering.

Polymer ScienceMaterials ScienceBlock Copolymer Self-AssemblyX-ray Scattering
Dr Alan Goddard

Dr Alan Goddard

Senior Lecturer, School of Biosciences

Dr Goddard's research interests focus around membrane proteins and the lipid membranes in which they reside.

Biological MembranesBiochemistryLipid MembranesMembrane Protein SystemsAntimicrobials
Andrew Devitt

Andrew Devitt

Professor, School of Biosciences

Professor Devitt's research over 20 years has focused on the innate immune system and its role in protection and tissue repair.

Extracellular VesiclesIntercellular Adhesion MoleculesMacrophagesApoptosisPhagocytes

You might also like...

Check out some other posts from Aston University

2 min

The Lost Girls of Autism – New book from Aston University emeritus professor Gina Rippon examines autism in women

The Lost Girls of Autism is published on 3 April 2025, coinciding with Autism Awareness Month in April In the book, Professor Rippon explores the ‘male’ history of autism, and why autism in women has been misunderstood and ignored Professor Rippon will give a free public lecture on the book at Aston University on 6 May 2025. Gina Rippon, professor emeritus of cognitive neuroimaging at Aston University Institute of Health and Neurodevelopment (IHN), has written a new book, entitled The Lost Girls of Autism. The book will be released on 3 April 2025, coinciding with Autism Acceptance Month in April. It has the subtitle ‘How Science Failed Autistic Women and the New Research that’s Changing the Story’. Historically, doctors believed that autism was a male condition, and simply did not look for it in girls and women. This has meant that autistic girls visiting a doctor have been misdiagnosed with anxiety, depression or personality disorders, or are missed altogether. Many women only discover they have the condition when they are much older, missing decades of support. In more recent years, it has become apparent that girls and women with autism have different traits and behaviours to boys and men, and are more likely to hide autistic traits to fit in – known as camouflaging. In The Lost Girls of Autism, Professor Rippon explores the emerging science of female autism, and examines why it has been systematically ignored and misunderstood for so long. Professor Rippon will give a free public lecture about her book on Tuesday 6 May 2025 at 18:00 BST at Aston Business School. Visit https://www.eventbrite.co.uk/e/the-lost-girls-of-autism-an-audience-with-author-gina-rippon-tickets-1304020734119 for more information and tickets. Copies of the book will be on sale at the event. Professor Rippon said: “This book reveals how a ‘male spotlight’ problem has biased many aspects of the autism story, from what autism is, to how we recognise it, and even how brain imagers like me search for answers. It shows how and why autistic women have been unrecognised, overlooked and unsupported. It shines a new light on how the story is changing and how we are now beginning to recognise the full spectrum of the autistic experience. It is for anyone with an interest in autism in all its presentations.”

3 min

How authorship language helped catch a domestic terrorist – new podcast

In the latest episode of Writing Wrongs, hosts Professor Tim Grant and Dr Nicci MacLeod interview Dr Isobelle Clarke to unravel a case where forensic linguistics helped track down and convict a dangerous individual. Episode three, Imposters Tending to the Wild with Dr Isobelle Clarke, dives into the chilling case of Nikolaos Karvounakis, a self-proclaimed anarchist who planted a viable explosive device in Princes Street Gardens, Edinburgh, in 2018. Karvounakis, a Greek national, evaded capture for years, hiding behind online anonymity and extremist rhetoric. However, forensic linguists stepped in to analyse his anonymous blog posts, revealing patterns in his language that ultimately helped Police Scotland link him to the crime. The case not only demonstrates how linguistic evidence can be a powerful forensic tool but also raises crucial questions about the role of language analysis in modern terrorism investigations. On 11 January 2018, a suspicious cardboard box was discovered in a public seating area in Edinburgh’s Princes Street Gardens. After a controlled explosion, investigators determined the device could have caused serious harm had it detonated. With no immediate leads, the investigation stalled - until an anonymous blog post surfaced, claiming responsibility for the attack. The post, written in both English and Spanish, was linked to an eco-anarchist group called Individualists Tending to the Wild, a Mexican-based extremist organisation advocating violent action against technological progress. Crucially, the post included an image of the bomb’s interior, a detail only the perpetrator or law enforcement could have known. Police Scotland sought the expertise of Professor Tim Grant, who analysed the text, producing a linguistic profile that suggested the writer was neither a native English nor Spanish speaker - but rather someone influenced by another language entirely. Two years later, police identified Nikolaos Karvounakis as a suspect. Using comparative authorship analysis, Professor Tim Grant compared his online writings - including song lyrics from his rock band - to the manifesto. By dissecting word patterns, grammatical structures and stylistic quirks, he established that Karvounakis was the likely author. This evidence -alongside forensic meteorology, which linked photos of clouds in Karvounakis’ blog posts to the same weather conditions on the day of the crime - was used to secure a warrant and seize computers containing known writings by Karvounakis. To eliminate inevitable bias that would result from having worked the case for more than two years, Professor Grant invited Dr Isabelle Clarke onto the case as an independent forensic linguist. Using a version of the General Imposters Method, a technique similar to a police lineup but for language, Dr Clarke confirmed that the writing style in the blog post was the closest to Karvounakis’ known writings. Police Scotland put the evidence in the case, including the linguistic evidence, to Karvounakis, and secured a guilty plea. In February 2022, Nikolaos Karvounakis was sentenced to over eight years in prison under the UK’s Terrorism Act. Tim Grant, professor of forensic linguistics at Aston University, said: “The case highlights the growing importance of forensic linguistics in solving crimes, particularly in an age where digital anonymity combines with extremist ideologies. “It also highlights the how different types of language analysis can assist as a case moves through different stages of investigation.” Dr Nicci MacLeod, deputy director of the Aston Institute for Forensic Linguistics, said: “This episode offers listeners a behind-the-scenes look at the forensic methods that expose deception, identify threats and ultimately bring criminals to justice.” Dr Isobelle Clarke, a lecturer in security and protection science at Lancaster University and one of the first graduates from the campus-based MA Forensic Linguistics programme at Aston University, said: “It was great to be back at Aston University talking about the Karvounakis case for the Writing Wrongs podcast. “It’s an interesting case to highlight, as it shows how different types of language analysis can help with police investigations.” Writing Wrongs is available on Spotify, Apple Podcasts and all major streaming platforms. Listeners are encouraged to subscribe, share and engage with the hosts by submitting their forensic linguistics questions. Whether it’s about this case or broader forensic linguistic techniques, Professor Grant and Dr MacLeod welcome inquiries from listeners.

3 min

Best-selling author Kate Summerscale joins Writing Wrongs to explore true crime and justice

The true crime podcast Writing Wrongs continues its exploration of language and justice with a special bonus episode featuring best-selling author and historian Kate Summerscale. Kate is an award-winning historian, journalist and best-selling author known for her meticulous research into historical true crime cases. Her book The Suspicions of Mr. Whicher won the Samuel Johnson Prize for Non-Fiction and was adapted into a major ITV drama. Her latest book, The Peep Show: The Murders at 10 Rillington Place, revisits the infamous Christie case, shedding new light on the victims’ lives, the social conditions of post-war Britain and the power of the press in shaping public perceptions of crime. In this episode, hosts Professor Tim Grant and Dr Nicci MacLeod explore a fresh perspective on the Rillington Place murders, the wrongful execution of Timothy Evans and how forensic linguistics has helped uncover the truth in criminal cases. Following on from the first episode of the series, which examined the Timothy Evans case and the origins of forensic linguistics, this conversation with Kate Summerscale provides fresh historical insights into one of Britain’s most infamous miscarriages of justice. The episode revisits the horrifying crimes of John Christie, whose calculated murders led to one of the most infamous miscarriages of justice in British history. The wrongful conviction and execution of Timothy Evans cast a long shadow over the UK’s legal system and played a pivotal role in the eventual abolition of the death penalty. Through expert discussion, the episode examines how Evans’ case became a turning point for criminal justice reform. The conversation also looks at the role of the media in shaping crime narratives. Sensationalist reporting during the Rillington Place murders fuelled public perceptions, sometimes distorting the truth in favour of dramatic storytelling. The episode draws comparisons between 1950s tabloid journalism and today’s true crime media, examining how crime reporting has evolved - and the ethical challenges it still faces. A deeply unsettling aspect of this case is its gendered nature. The majority of John Christie's victims were vulnerable women, many facing financial and social instability. The episode delves into how structural inequalities, from the lack of legal abortion to economic dependence, made women more susceptible to predatory figures like Christie, a pattern that remains relevant in crime analysis today. Finally, the episode scrutinises government complicity in covering up a miscarriage of justice. The Brabin Inquiry, launched in the 1960s, sought to reexamine Evans’ conviction but delivered a highly controversial conclusion, failing to fully exonerate him. The discussion highlights how political interests and legal reputation management influenced the case’s outcome, leading to Evans’ eventual posthumous pardon - but not a full legal exoneration. Tim Grant, professor of forensic linguistics at Aston University, said: “It was wonderful to have Kate on Writing Wrongs. “Her work challenges the traditional true crime narrative, shifting focus from the murderer to the victims and the broader social structures that allow such crimes to happen. “Her insights in this episode provide a fresh and deeply researched perspective on a case that still haunts British legal history.” Writing Wrongs is available on Spotify, Apple Podcasts and all major streaming platforms. Listeners are encouraged to subscribe, share and engage with the hosts by submitting their forensic linguistics questions. Whether it’s about this case or broader forensic linguistic techniques, Professor Grant and Dr MacLeod welcome inquiries from listeners.

View all posts
Powered by