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Thousands of men to trial prostate cancer home testing kit
Thousands of men worldwide are to receive a home test kit for prostate cancer – thanks to pioneering research from the University of East Anglia and the Norfolk and Norwich University Hospital (NNUH). The research team are trialling a new home-testing ‘Prostate Screening Box’ to collect men’s urine samples at-home. The urine samples will be used to analyse the health of the prostate in 2,000 men in the UK, Europe and Canada. This simple urine test is intended to diagnose aggressive prostate cancer and in a pilot study predicted which patients required treatment up to five years earlier than standard clinical methods. Lead researcher Dr Jeremy Clark from the University of East Anglia 'unboxes' the new home testing kit live on Sky News. The Prostate Screening Box has been developed in collaboration with REAL Digital International Limited to create a kit that fits through a standard letterbox. It means that men can provide a urine sample in the comfort of their own home, instead of going into a clinic or having to undergo an uncomfortable rectal examination. The research team hope that it could revolutionise diagnosis of the disease. Lead researcher Dr Jeremy Clark, from UEA’s Norwich Medical School, said: “Prostate cancer is the most common cancer in men in the UK. However it usually develops slowly and the majority of cancers will not require treatment in a man’s lifetime. It is not a simple matter to predict which tumours will become aggressive, making it hard to decide on treatment for many men. “The most commonly used tests for prostate cancer include blood tests, a physical examination known as a digital rectal examination (DRE), an MRI scan or a biopsy. “We have developed the PUR (Prostate Urine Risk) test, which looks at gene expression in urine samples and provides vital information about whether a cancer is aggressive or ‘low risk’. “The Prostate Screening Box part sounds like quite a small innovation, but it means that in future the monitoring of cancer in men could be so much less stressful for them and reduce the number of expensive trips to the hospital. “The prostate lies just below the bladder. It constantly produces secretions which naturally flow into the urethra - the tube through which urine passes from the bladder. The prostatic secretions carry cells and molecules from all over the prostate which are flushed out of the body on urination. We collect these and examine them. It’s a way of sampling the whole prostate in one go. “As the prostate is constantly secreting, the levels of biomarkers in the urethra will build up with time. Collecting from the first wee of the day means that overnight secretions can be collected which makes the analysis more sensitive.” The team have previously trialled the kit with a small group of participants, but in the next phase of the research study are rolling it out to thousands. Men taking part in the trial will receive a home urine-sampling kit and will be asked to provide two urine samples – one to be taken first thing in the morning and the second an hour later. The samples will then be sent back to the lab for analysis. Dr Clark said: “Feedback from early participants showed that the at-home collection was much preferred over sample collection in a hospital. “We hope that using our Prostate Screening Box could in future revolutionise how those on ‘active surveillance’ are monitored for disease progression, with men only having to visit the clinic after a positive urine result. “This is in contrast to the current situation where men are recalled to the clinic every six to 12 months for a range of tests including DRE, PSA tests, painful and expensive biopsies and MRI. We are working to develop the test to help patients in three years’ time. “A negative test could enable men to only be retested every two to three years, relieving stress to the patient and reducing hospital workload,” he added. Robert Mills, Consultant Clinical Director in Urology at NNUH, said: “This simple, non-invasive urine test has the potential to significantly change how we diagnose and manage early prostate cancer for the benefit of patients and health care systems. It may enable us to avoid unnecessary diagnosis of low risk disease as well as managing patients more appropriately with surveillance for those with low risk of progression and early curative treatment for those at high risk of progression.” Paul Villanti, executive director of programs at Movember, said: “The PUR test has great potential to transform the way prostate cancer is managed. Not only can it accurately predict when a man’s disease will become aggressive and require treatment, but it has the added advantage of allowing men to complete it at home. “We are proud to have supported the development of the PUR test from its early stages as part of our Global Action Plan on Biomarkers, through to this trial involving thousands of men across the world. “Through our Global Action Plan on active surveillance, we have been able to identify hundreds of men from the UK, Germany, Italy and Canada who are suitable to take part in this trial. “We hope it will speed up the trial’s progress and get this test included as part of clinical care for men as quickly as possible.” The research has been funded by a Movember and Prostate Cancer UK Innovation award, the Masonic Charitable Foundation, the Bob Champion Cancer Trust, the King family, the Andy Ripley Memorial Fund, the Hargrave Foundation, Norfolk Freemasons and the Tesco Centenary Grant.

Novel coronavirus discovered in British bats
A coronavirus related to the virus that causes Covid-19 in humans has been found in UK horseshoe bats – according to new collaborative research from the University of East Anglia, ZSL (Zoological Society of London), and Public Health England (PHE). However, there is no evidence that this novel virus has been transmitted to humans, or that it could in future, unless it mutates. UEA researchers collected faecal samples from more than 50 lesser horseshoe bats in Somerset, Gloucestershire and Wales and sent them for viral analysis at Public Health England. Genome sequencing found a novel coronavirus in one of the bat samples, which the team have named ‘RhGB01’. Due to the rapid response nature of this research, it has not yet been peer reviewed. It is the first time that a sarbecovirus (SARS-related coronavirus) has been found in a lesser horseshoe bat and the first to be discovered in the UK. The research team say that these bats will almost certainly have harboured the virus for a very long time. And it has been found now, because this is the first time that they have been tested. Importantly, this novel virus is unlikely to pose a direct risk to humans, unless it mutates. A mutation could happen if a human infected with Covid-19 passes it to an infected bat, so anyone coming into contact with bats or their droppings, for example those engaged in caving or bat protection, should wear appropriate PPE. Prof Diana Bell, an expert in emerging zoonotic diseases from UEA’s School of Biological Sciences, said: “Horseshoe bats are found across Europe, Africa, Asia and Australia and the bats we tested lie at the western extreme of their range. “Similar viruses have been found in other horseshoe bat species in China, South East Asia and Eastern Europe. “Our research extends both the geographic and species ranges of these types of viruses and suggests their more widespread presence across more than 90 species of horseshoe bats. “These bats will almost certainly have harboured this virus for a very long time – probably many thousands of years. We didn’t know about it before because this is the first time that such tests have been carried out in UK bats. “We already know that there are different coronaviruses in many other mammal species too,” she said. “This is a case of ‘seek and you will find’. “Research into the origins of SARS-CoV-2, the virus that causes Covid-19 in humans, has focussed on horseshoe bats - but there are some 1,400 other bat species and they comprise 20 per cent of known mammals. “Our findings highlight the need for robust genotype testing for these types of viruses in bat populations around the world. And it raises an important question about what other animals carry these types of viruses.” Prof Andrew Cunningham, from the Zoological Society of London, said: “Our findings highlight that the natural distribution of sarbecoviruses and opportunities for recombination through intermediate host co-infection have been underestimated. “This UK virus is not a threat to humans because the receptor binding domain (RBD) – the part of the virus that attaches to host cells to infect them - is not compatible with being able to infect human cells. “But the problem is that any bat harbouring a SARS-like coronavirus can act as a melting pot for virus mutation. So if a bat with the RhGB01 infection we found were to become infected with SARS-CoV-2, there is a risk that these viruses would hybridise and a new virus emerge with the RBD of SARS-CoV-2, and so be able to infect people. “Preventing transmission of SARS-CoV-2 from humans to bats, and hence reducing opportunities for virus mutation, is critical with the current global mass vaccination campaign against this virus.” Prof Bell added: “The main risks would be for example a bat rehabilitator looking after a rescued animal and infecting it with SARS-CoV2 - which would provide an opportunity for genetic recombination if it is already carrying another sarbecovirus. “Anyone coming into contact with bats or their droppings, such as bat rescuers or cavers, should wear appropriate PPE – in order to reduce the risk of a mutation occurring. “We need to apply stringent regulations globally for anyone handling bats and other wild animals,” she added. The new virus falls within the subgroup of coronaviruses called sarbecoviruses which contains both SARS-CoV-2 (responsible for the current pandemic) and SARS-CoV (responsible for the initial 2003 SARS outbreak in humans). Further analysis compared the virus with those found in other horseshoe bat species in China, South East Asia and Europe and showed that its closest relative was discovered in a Blasius’s bat from Bulgaria in 2008. Ivana’s story The UK discovery was made by undergraduate ecology student Ivana Murphy, from UEA’s School of Biological Sciences, who collected bat droppings as part of her final year research dissertation. Jack Crook conducted the genetic analyses in partnership with other researchers at PHE. A total of 53 bats were captured, and their faeces collected in sterile bags. The research was conducted under strict Health and Safety protocols. Full PPE was worn and Ivana was regularly tested for Covid-19 to avoid any chance of cross contamination. The bats were released immediately after their droppings had been collected. Ivana said: “I am very fortunate to be surrounded by so many experts in their fields, which has allowed me access to resources that many undergraduates wouldn’t have. I feel extremely lucky to have been able to conduct such an advanced study.” “We weren’t shocked by the results, but I am extremely eager to carry out further research. “I chose to study ecology at UEA as I have a passion for trying to protect and conserve nature. I wanted a better understanding of the global situation and so chose UEA to study ecology and conservation. “The plan after graduation is to do an extended study of viruses in UK bats, very similar to the one I carried out as an undergraduate. There is still a lot more to understand and I am extremely excited to see what else we can find out.” But she says that she doesn’t want her research to turn people against bats. “More than anything, I’m worried that people may suddenly start fearing and persecuting bats, which is the last thing I would want and would be unnecessary. As like all wildlife, if left alone they do not pose any threat.” ‘Metagenomic identification of a new sarbecovirus from horseshoe bats in Europe’ is published on the Research Square pre-print server. Read the full story, including a Q&A with all you need to know.

COVID expert: Prof Lawrence Young, UK
Professor Lawrence Young of the University of Warwick is one of the go-to experts in the UK on COVID-19. A Professor of Molecular Oncology at Warwick Medical School, he can comment on many aspects of the pandemic -- from the nature of the virus itself and its effects in patients, to its impacts on hospitals and wider society. He regularly features on TV, radio, and newspapers in the UK and worldwide, including: If you would like to book an interview with Prof. Young, contact press@warwick.ac.uk or L.Walton.1@warwick.ac.uk

News of the newly proposed European Super League has left a storm of concern, criticism, threats and even political intervention in its wake. The announcement of a mid-week league consisting of a dozen of the top-tiered clubs from across Britain and Europe would rival the popular UEFA Champions League. No doubt, more football to watch is good for fans, and for club owners – but the backlash has been harsh from other stakeholders and teams left on the sidelines. The media coverage has been intense. Meanwhile, UK Prime Minister Boris Johnson met with the Football Association, Premier League officials and fans' representatives on Tuesday, after which the government said it will take "whatever action necessary", including legislative options, to ensure the proposals were stopped. Downing Street added: "No action is off the table." In other developments: Uefa president Aleksander Ceferin called on the English clubs to "come to your senses" Everton criticised the "preposterous arrogance" of the clubs involved Real Madrid president Florentino Perez said that the new league was needed to "save football" The proposed tournament would see teams play one another in midweek games in an attempt to have more matches between the big-name clubs. The other clubs involved are AC Milan, Atletico Madrid, Barcelona, Inter Milan, Juventus and Real Madrid. The plans have been heavily criticised by fans, pundits, football's governing bodies and members of the UK government. "It is our task to protect the European sport model. If some elect to go their own way, they must live with the consequences of their choices," said Infantino, the president of world football's governing body. "They are responsible for their choice completely. This means you are either in or you are out. You cannot be half in and half out." April 20 – BBC If you are a journalist covering this emerging story – then let us help with your questions by providing expert opinion, perspective, and analysis. Peter Dawson from the University of East Anglia is a Professor of Economics and an expert in sports economics. Peter is available to speak with media about this topic – simply click on his icon now to arrange an interview today.

Are vaccine passports legal in a post-COVID-19 era? Let our experts explain
As America and the world look to slowly round the corner of the safety measures enacted during the COVID-19 pandemic, the new coronavirus vaccines are giving hope of an eventual return to normal. However, with an active anti-vaccination movement afoot and many still skeptical of getting that essential poke in the arm, the World Health Organization said some government officials are suggesting the idea of vaccine passports. A simple piece of identification would end the uncertainty that comes with travel, work and the much sought-after leisure that often means crowded places and smaller spaces. The idea has already caught on in countries in Europe and South America. It may be the safety blanket many seek, but are vaccine passports actually legal? It is a question that’s beginning to get serious coverage. “Having proof of vaccination can be essential for a number of sectors other than health, but we cannot overlook the potential discriminatory consequences that may arise,” said Dr. William Hatcher, an expert in public policy and interim chair of the Department of Social Sciences at Augusta University. Another idea being floated is immunity passports, but Hatcher suggests¬ allowing only people with immunity to work might disadvantage those who haven’t gotten sick or those without the antibodies to prove it. It’s as if, in the eyes of their employer, their lack of infection constitutes a disability. The inequality that immunity passports could foster in these situations may be illegal under the Americans with Disabilities Act. There are also other ethical, practical, and cultural aspects to consider as well. If you are covering this emerging topic and are looking to know more, our experts can help. Dr. Hatcher is a professor of political science and interim chair of Augusta University’s Department of Social Sciences. He is an expert in the areas of public administration and social, economic, and political institutions in local communities. Hatcher is available to speak with media regarding the concept of vaccination and immunity passports. To arrange an interview, simply click on his name.

U.S.-Iran Crisis: Outlook and Implications
Executive Summary: The immediate crisis following the death of Iranian general Qassem Soleimani in a U.S. airstrike and Iran’s retaliatory missile strikes against two U.S. airbases appears to have settled down. However, the conditions for a future flare-up remain in place because the underlying conditions have not changed. Going forward, each side is likely to double down on its stated strategic objective, with Iran pushing for an end to U.S. presence in the region and the U.S. pushing for an end to the Iranian nuclear program. Further, the norms that had previously prevented an open exchange of fire between the two sides have been eroded. Why It Matters: The events of January 3rd and 8th represent the first time since the skirmishes of the “Tanker Wars” of 1987-88 that the military forces of the United States and Iran have directly and openly exchanged fire with each other. For the last three decades, the contest between the two states has been a shadow war of proxy conflicts, plausible deniability, and non-military measures. The American decision to strike Soleimani and the Iranian decision to fire missiles in response removed many of the guardrails that have set limits on previous escalations of tensions. The Iranian decision to renounce cooperation with the 2015 nuclear agreement places back into contention an issue that had previously brought the U.S. and Israel to the point of war with Iran in 2012-13. Business Impact: Markets have been largely taking a wait-and-see approach in order to determine the form of Iranian response to Soleimani’s death, and they responded with relief when President Trump signaled that the U.S. would not retaliate. To an extent, uncertainty in the Middle East had already been priced into the markets due to tensions in the second half of 2019. A significant or prolonged conflict would have an obvious negative impact on energy markets and regional economies. In addition, American and Western companies operating internationally or their employees could suffer collateral damage from any future Iranian proxy attacks against visible symbols of U.S. presence overseas. Looking Forward: In the immediate term, the resolution of the crisis represented one of the best possible outcomes: Iran has publicly signaled that the missile launches conducted on January 8th constituted the extent of their military retaliation to Soleimani’s death and President Trump’s White House address acknowledged Iran’s desire to de-escalate and spoke of finding mutually beneficial outcomes with no further mention of military action. Going forward, both Iran and the United States are likely to double down on their desired strategic outcomes. Iran will seek to use all of the levers of its influence to drive the United States from the region, beginning with Iraq but also including indirect pressure on the Gulf states that host U.S. forces. Offensive cyber operations and deniable proxy attacks against civilian infrastructure in the Gulf could be part of that campaign, returning to tactics observed in the past. For its part, the United States will continue its maximum pressure campaign over the Iranian nuclear program, with President Trump promising additional economic sanctions even as he stepped back from military action. Therefore, although both sides appear to be committed to non-military means, the points of tension that caused the most recent crisis are all still present and have arguably increased based on Iran’s increased non-compliance with JCPOA. It remains to be seen whether coming close to the brink of open conflict will have changed the risk tolerance of either side or whether the first acknowledged exchange of fires between the U.S. and Iran for 32 years will usher in a new period of low-level conflict. The View from Tehran: Iran has played Soleimani’s death for maximum strategic benefit. The messaging of the past 96 hours was aimed at various audiences within the country, the region, and around the world. Having been caught on the backfoot by the U.S.’s strike on Soleimani, the Supreme Leader allowed the IRGC to retaliate against U.S. forces in Iraq in a calibrated manner, likely calculating that a strike with limited casualties would satisfy demands for vengeance while not prompting a response. Khamenei’s Decision: Ayatollah Khamenei is an inherently conservative figure and one who is above all else motivated by the priority of regime survival. Given their long-standing personal relationship, there is ample reason to believe that his displays of emotion of Soleimani’s death, including weeping over his coffin during the funeral on January 6th, were genuine and heart-felt. However, his expressed desire for revenge has been tempered by the overarching imperative to avoid a conflict that would have threatened the regime’s hold on power, either from within or without. Rally Around the Flag: Within Iran, the regime is seeking to use Soleimani’s death and their subsequent retaliation to build national unity following a period of significant domestic unrest. This has been emphasized by the extended period of mourning for Soleimani, days-long funeral spectacle, and the invocation of religious and cultural symbols associated with Shi’a martyrs. The death of Soleimani comes on the heels of a series of mass protests in Iran that originally began on November 15th in response to proposed increase in the price of gas, but which have since expanded to a wider challenge to the regime. Media reporting from late December suggested as many as 1,500 Iranian civilians have been killed as part of a regime crackdown on the protests, which have been characterized as the most serious challenge to the regime since the Green Movement of 2009. JCPOA as a Wedge Between U.S. and Europe: Iran announced on January 5th that it would cease compliance with the remaining provisions of the 2015 Joint Comprehensive Plan of Action but would be willing to return to compliance if sanctions are removed. The nuance in Iran’s position highlights the fact that it is continuing to attempt to use the nuclear issue to drive a wedge between European signatories to the agreement and the United States, which unilaterally walked away from the treaty in May 2018. Regime Dynamics: Soleimani was a high-profile figure within Iran, but his outsized influence on Iranian foreign policy also created friction with other stakeholders in the regime, including leaders of the conventional military forces, the ministry of foreign affairs, and the intelligence services. He was one of few genuinely strategic thinkers in the Iranian national security apparatus and the one with the most extensive and deepest connections within the Arab-speaking world. His replacement as commander of the Quds Force is his long-time deputy who will be familiar with the day-to-day operations of the IRGC’s external operations arm but will not have the stature or the network of Soleimani. As a result, other stakeholders may jockey to move into the vacuum created by his death. The View from Washington: The present challenge for the U.S. is how to maintain both a deterrent posture and establishing the means to avoid further escalation. The policy on Iraq going forward will have to balance President Trump’s desire to disengage from the conflict while not creating the appearance of having been pushed out by Iran. Escalate to Deter: President Trump’s decision to kill Soleimani reflected an “escalate to deter” strategy, using a sudden and unexpected escalation of force during a crisis in order to reestablish deterrence after previous provocations in 2019 had gone largely unanswered. However, deterrence is only as good as the last demonstration of a willingness to respond. The decision to not respond to Iran’s retaliatory missile strikes reflected a pragmatic decision to de-escalate. National Security Decision-Making: Nearly three years into his presidency, Donald Trump feels increasingly confident making national security decisions based on his own instincts. The original coterie of experienced national security establishment members such as Jim Mattis and H.R. McMaster who had populated the Situation Room during the early days of the administration have largely resigned or been fired and replaced with individuals of lower profile and/or proven loyalty. Although the mechanisms of the formal interagency process continue to function, President Trump increasingly makes decisions based on a network of informal advisors and media sources. Domestic U.S. Considerations: The decision to launch the strike on Soleimani came during a period of high political tension in Washington, as it had been expected this month that the U.S. Senate would begin a trial in response to articles of impeachment passed by the House of Representatives in December. The Soleimani strike is being taken up by both Trump’s supporters and opponents as evidence of either his credentials as a decisive commander-in-chief or his unsuitability for office, depending on their perspective. Congress has proposed votes to limit President Trump’s independent authority to initiate hostilities with Iran, but this is unlikely to gain traction in the Senate. Separately, the first voting in the Democratic primary is less than one month away, and a sudden shift in focus to national security issues could have results that are difficult to predict, either boosting those with national security credentials (such as former vice president Joe Biden and military veteran Pete Buttigieg), or rallying support among primary voters for anti-war (such as Bernie Sanders). Third-Party Perspectives and Responses: Iraq: The strike at Baghdad International Airport that killed Soleimani also killed the deputy commander of Iraq’s Popular Mobilization Front, a coalition of militias that forms a part of Iraq’s official security apparatus. Iraq’s new Prime Minister Adel Abdul Mahdi has condemned the attack as a “massive breach of sovereignty” and an “aggression on Iraq”. Iraq’s parliament passed a draft law on January 5th calling for the removal of all foreign troops from Iraqi soil, but the law was non-binding and the session had been boycotted by most of the Sunni and Kurdish members of the legislature. Iranian presence has also been the recent target of Iraqi ire, such as in November when a crowd of Iraqis burned down the Iranian consulate in the Shi’a holy city of Najaf, and the Iraqi government will likely try to play both sides against each other to maximize its leverage for military and financial support. Withdrawal from Iraq would mean that the remaining American forces in Syria could no longer be supplied or supported through the western desert of Iraq and would therefore also have to be withdrawn. Iran will likely seek to use all its considerable levers of influence in Iraq to convince the government to see through the expulsion of American forces. The United States leaving Iraq and Syria due to Soleimani’s death would be a fitting legacy from the Iranian perspective and a perverse one from the American perspective given that Soleimani was responsible for the deaths of hundreds of American servicemembers in Iraq (and thousands of Iraqi civilians) through his support for Shi’a militias in the mid-to-late 2000s. Europe: Statements from European capitals emphasized the need for restraint and de-escalation. French President Macron is likely to view this event as further justification for his proposals that the EU develop a defense and security apparatus independent of NATO in order to avoid being entangled by potentially reckless American actions. Iran will likely continue to use this event as an opportunity to drive a wedge between the U.S. and Europe on the nuclear program and other issues, and their chosen retaliation was likely calibrated at least in part to allow them to continue positioning themselves as a responsible actor. For his part, Trump is urging the European signatories to join him in walking away from the JCPOA in order to increase Iran’s international isolation. United Kingdom: The British government has tried to tread a fine line in its responses to the strike, with Prime Minister Johnson calling for de-escalation while also stating that he “will not lament” the fact that Soleimani is dead. The U.K. is likely trying to balance its desire to remain aligned with France and Germany in trying to keep the JCPOA together with its traditional close alliance with the United States and Johnson’s personal relationship with President Trump. Russia: Unsurprisingly, Russian President Vladimir Putin condemned the American strike, which removed a valuable interlocutor for Russian forces in Syria. Russian troops and Iranian-backed militias in Syria had periodically found themselves with diverging interests in their campaign to support the Assad regime, and Soleimani performed a critical function in directing the activities of those militias to ensure that both Russia and Iran achieved their strategic objectives in Syria. A potential American withdrawal from Iraq and Syria would advance Russia’s interest in establishing itself as the indispensable foreign power in resolving the crisis in Syria and within the region more broadly. China: In line with their long-standing principle of non-intervention and their own interest, China condemned the strike, but the response was muted overall. Chinese interests are primarily economic and tied to ensuring a steady supply of petroleum. One of China’s newest and most capable naval destroyers recently participated in trilateral naval exercises with Iran and Russia in the Gulf of Oman. Although such exercises primarily serve a strategic messaging and diplomatic function, they do signal an emerging alignment of interests between the three states that would be significant for the response to any future crises.

COVID-19 has raised the stakes for boards, argues Brunswick’s Paddy McGuinness, former UK Deputy National Security Adviser. We now live with COVID-19. Fewer business leaders are making the mistake of talking about “post-COVID” or “when this is over.” The better of them have factored in COVID-19 related constraints to their medium-term plans and are even thinking about how the world may change in the long-term. They are building capacity to take advantage of an early recovery within months, yet they are modeling and encouraging grit for current and indeed harder conditions to last much longer. In the past, when health emergencies—say the Spanish Flu pandemic of a century ago—subsided, there was a greater return to economic normality than had been expected during the crisis. Extreme events often heighten or even distort our perception of wider risks. That old journalistic cliché “one thing is certain, nothing will be the same again” is rarely true. But the pandemic has created the expectation that businesses will be resilient—that they will be able to respond to an event and recover to the state prior to the event, incorporating the lessons learned into business practice. Many business leaders feel they have not done too badly responding to a once-in-a-hundred-years event. Business Continuity Plans (BCPs), which were understandably sketchy for pandemics, were pulled out of second-line risk management and owned and improved in real-time by executive committees. The transition to remote working and, at least in Asia and some of Europe, the gradual return to offices again, has been managed. Services and even vital production have been maintained. Leaders have absorbed the personal and collective strain of this. Good reason then for some satisfaction as they delegate certain COVID-19 responses and focus on the economic tsunami that follows the pandemic. The public seems to largely agree with business leaders’ assessments. While many national and scientific leaders find themselves beset by “blamestorming,” corporate executives have been given more slack. They weren’t expected to have foreseen a pandemic. Their sometimes scrabbling responses are understood. However, behind this lucky pass lurks an expectation that businesses will now be more prepared for crises and foreseeable risks. Resilience cannot be relegated to BCPs and traditional risk-management structures. It is categorically a board issue—regulators, lawyers, politicians and the public say so. The reputations of individual board members and the collective are at stake. Think how fast leaders have been expected to respond to the issues raised by the Black Lives Matter movement. Alacrity will be required. The speed and scale of decisions in response to the pandemic leaves board committees playing catch up to assure themselves that risks have been managed. The move to working from home has been rapid, so too the digitization of the business. Some see these as new, streamlined ways of working, yet the negative consequences are not yet fully apparent. Working from home, for instance, is attractive to some employees as well as chief financial officers, who may relish the chance to reduce fixed costs. Concerns about the impact on the coherence of the business’s culture, its productivity and innovation, the security of data held at home, hardships for those in difficult home conditions, and, indeed, the needs of the younger demographic who seem to favor a return to the office, need to be given due consideration. It may be a case of “decide in haste, repent at leisure.” Resilience is categorically a board issue—regulators, lawyers, politicians and the public say so. The reputations of individual board members and the collective are at stake. Boards also need assurance that the business has regained its balance and can manage parallel or interrelated crises. In recent weeks we have been helping several clients respond to major cyber events unrelated to the COVID-19 outbreak. They have probably needed more external support than otherwise because their leadership capacity was inevitably denuded by pandemic response. And they have benefitted from us already knowing each other and having experience of how to work together in crisis. After the Great Financial Crash there was a heavy focus on balance-sheet resilience and having the requisite finance skills on boards. Business leaders are now beset by advice on the heightened obligation to be resilient in much a broader sense of the word. Regulators, lawyers and risk consultants are sharing checklists of factors for executive committees to take into account when managing risks and for boards to oversee. The challenge here is defining what changes your specific business needs and how to actually bring those about. Shareholders will be expecting a judicious move away from “just in time” systems to ones that can endure foreseeable risks. This isn’t just about potential legal liability or reputational risk. This is about setting your business culture for success. Undermanage risks and the business is wide open to damage from foreseeable shocks with all the loss of confidence and capability that follows. Overmanage and the business losses its competitive edge just when there is opportunity in the recovery. In order to track broader resilience, boards and their committees will need access to a wider set of skills and insight. Board membership emerges as an obvious area of focus. Yet each board will take more time and belonging to too many—“over boarding”—may well be unacceptable. Risk methodology and information flows will also have to be reviewed, alongside how to strengthen board members’ awareness and skills. Before the pandemic, chairs and CEOs were already wrestling with this for their difficult-to-price risks, such as data, technology risks and cyber. Individual experts on boards created siloed responsibility for what should have been a shared risk. A focus on process and method often led to a focus on the management, rather than genuine oversight of, risks. External advice didn’t always help (as we have learned from the plethora of competing advice around COVID-19). No single intervention will meet the new standard for resilience. Nor will simple prescription. A broader and more articulated approach is required if governance is to maintain stakeholder confidence and corporate reputation.

Resilience in the Face of COVID-19
Brunswick Senior Advisor Paddy McGuinness, former UK Deputy National Security Adviser, on how businesses can chart a course amid the fear and uncertainty. We are all becoming more familiar with this disease than we care to be—and may become yet more so. Still uncertainty remains. It began even with the terminology. Coronavirus is a descriptor, a general term. Under the microscope, the virus has crown-like spikes, hence corona. The common cold and variances of it are coronaviruses. COVID-19 (as in Corona Virus Disease 2019) is the effect that this particular coronavirus has on the human being—that’s the disease the world’s grappling with. That’s the distinction between the two terms. We’ve now spoken to more than 150 clients about their situation. That has given us a broad view of the corporate response across affected geographies from Asia, through the Middle East and Europe to the Americas, a window into how those responses have played out and the challenges continually unfolding. Here’s what we’ve been advising our clients: First, develop a single view that’s grounded in professional, well-sourced information. In government we called this “a commonly recognized information picture.” That view has to be based on the responsible medical experts: the World Health Organization, the Center for Disease Control, Public Health England and similar bodies. You do not get it from the newspapers, from social media, from friends, or even your local medic. You operate on the basis of informed medical and public health advice. The current vocal challenge to that advice in Europe and the US is not reason to depart from it as your foundation for the actions you take. A leadership team needs to develop the discipline to clarify that generic narrative into a specific frame for their business context and then operate within it. It’s dangerous for leaders to start pretending they’re epidemiologists. Have a single view and stick to it. I’ve been on calls with leadership teams where there’s agreement on that view and then someone says, “But I read that the disease ...” Don’t go there. Don’t work on that basis. The uncertainty is difficult enough to deal with. Don’t add to it. You will be focused first on the safety—the human consequences—of your course of action and then on the resilience of your business. That may cause you to anticipate some of the “Non Pharmaceutical Interventions” that government makes. Brunswick has. Having established your position, think through how you’re going to communicate it to employees, customers, and investors. What about your suppliers and regulators? How might you engage with local public health officials and local authorities? Exaggeration and understatement are equally unhelpful. These engagements need to be tailored, yet aligned within your broader narrative. Leaders also need to plan for reasonable worst-case scenarios. Covid-19 has already spread in a way that we hoped wouldn’t happen, and in a way that standard business continuity planning doesn’t cover. Now, many in the workforce have to work from home. Among other considerations, that produces additional cyber and data vulnerability. What if schools close and your employees have children at home they have to look after? What will your IT capabilities be if 20 to 40 percent of your team is incapacitated at any one time during the peak period? Are your HR teams prepared to deal with the most unfortunate case, where employees or their close relatives pass away? In extreme times, it can be tempting to take extreme positions. A lesson of crises is never to enter into something without knowing how you’re going to get out of it, how to reverse it. If companies are going to start shutting down their operations, how are they going to open again? On what justification? Taking fixed positions amid great uncertainty can prove restrictive—or counterproductive—when circumstances change. Resilience is the ability to respond and recover to the state prior to the event, having learned the lessons of the event. Respond and recover—that’s the long-term goal here. Covid-19 will pass. We know from other pandemics that recovery does come. How can you position yourself to take advantage of that recovery, to get back with speed and strength? Because some companies will. Now more than ever senior leaders need to talk about how things will be the other side of the crisis and to describe signs of recovery. This is easiest for enterprises with transnational reach. They recount what is happening in Asia as the disease passes so that European and US stakeholders can see beyond the immediate demands of emergency response. On a personal level, stick close to the medical experts and the people who know what they’re talking about. I may well get Covid-19 here in the United Kingdom. I assume that, like the vast majority of healthy people who get it, I will experience mild to moderate symptoms and recover just fine. If I don’t, I want health services to be available. I want the spread to be managed at sustainable levels, so I am doing what Government asks of me and avoiding all but essential contact with others and unnecessary travel. I expect that more will be asked of me, my family and colleagues before we are through this. I wouldn’t let Covid-19 overwhelm you in your daily life, given what we know. That’s certainly my intention: carry on with as much normality as possible, support others and use the unexpected circumstances to prepare for the recovery phase which will come.

Volunteers receiving government aid while unemployed face scrutiny, bias from public
With the worldwide spike in unemployment caused by the COVID-19 pandemic, many people may turn to volunteerism as a way to pass their newly found free time. But new research suggests that volunteers who also receive government aid are often judged negatively as "wasting time" that could be used to find paid employment. "We found that aid recipients are scrutinized to a greater extent than those who are working, including the underemployed, with observers demonstrating a strong bias toward believing that aid recipients should be using their time to pursue employment opportunities above all else," said Jenny Olson, an assistant professor of marketing at the Indiana University Kelley School of Business and corresponding author of the research forthcoming in the International Journal of Research in Marketing. "This is beyond education, personal leisure, and spending time with family and friends. "As a result, they are given less latitude in how they use their time, and can even be seen as more moral for choosing not to engage in prosocial behaviors, when such behaviors take time away from gaining paid employment," Olson added. "The simple act of volunteering among aid recipients -- versus not mentioning volunteering -- not only shapes judgments of the individual aid recipients, but this information can also impact views toward federal tax policy more broadly." Although volunteering is a positive activity that partially combats the negative stereotype of a welfare beneficiary, Olson and her colleagues found that it also sparks anger among observing consumers, with aid recipients being perceived as being "less moral for choosing to volunteer." Factors that minimize these judgments include being perceived as taking strides toward gaining employment via education and being perceived as unable to work. Other co-authors of the paper, "How Income Shapes Moral Judgments of Prosocial Behavior," are Andrea Morales of Arizona State University, Brent McFerran of Simon Fraser University in Canada and Darren Dahl of the University of British Columbia. The research was supported in part by grants from the Social Sciences and Humanities Research Council of Canada. According to a 2019 report from the Organisation for Economic Cooperation and Development, public spending on government assistance averaged more than 20 percent across 36 countries in 2018. Many countries -- including those in Asia, Europe, and the Americas -- have seen a rise in the number of people receiving benefits over the years, a total now reaching into the billions. The extent to which the welfare state is supported depends, in no small part, on public sentiment. Previous research has shown that support for government spending on welfare programs is directly related to how the voting public perceives the beneficiaries. This is the first paper to document a link between prosocial behavior and support for federal spending on welfare programs. "Given that individuals perceive opportunity costs for their own time, it stands to reason that they perceive them for others as well," Olson said. "Because government programs are supported by 'their' taxpayer dollars, observers often feel justified in suggesting how aid recipients spend their time." The research shows that consumers prefer different patterns of tax redistribution as a function of viewing aid recipients making nonfinancial choices. Specifically, consumers support allocating fewer tax dollars toward supporting government assistance programs after hearing about an aid recipient who volunteers his time. Researchers conducted nine studies across three countries. They randomly presented participants with scenarios about hypothetical aid recipients and asked them to offer judgment about how the recipients used their time, such as engaging in volunteer activities or sending out resumes. Participants were asked how they viewed target individuals on a morality index and how they felt about them emotionally. For interviews with Jenny Olson, contact George Vlahakis at 812-855-0846 or vlahakis@iu.edu.

Scapegoating During Pandemics Has Always "Plagued" Humanity
Though it was widely known that the first known cases of coronavirus could be traced back to Wuhan in China, many Americans were shocked and saddened to hear President Donald Trump repeatedly calling the illness the "Chinese virus" during a news conference in March. Though President Trump has insisted it's "not racist at all," Asian-Americans have reported incidents of slurs and physical abuse over the perception that China caused COVID-19. Rev. Joseph Ryan, OSA, PhD, teaches a course on the history of disease, with a focus on the bubonic plague, and notes that this type of xenophobic hysteria is not new when it comes to pandemics. “A theme that we can see with these epidemics is hysteria and the scapegoating of people who are liminal and have no defenders,” says Fr. Ryan. “We also see nativism and xenophobia evident in people's response to epidemic illness. Pandemics test the humanity of human populations and sometimes we are inhumane in the face of the fear of death from such diseases.” Here are a few examples from history of how humanity shifts blame during times of great pandemic-related stress: 1348: The Bubonic Plague A third of Europe's population was eliminated by this epidemic, which spread along trade routes. The event caused different expressions of hysteria among Europeans, including the persecution of the Jewish community. 1832: Cholera Like the bubonic plague, cholera traveled along trade routes. In the United States, Irish immigrants were scapegoated. 1918: Spanish Influenza It gained its name because the first journalists to talk about the disease were from Spain. Influenza came from Kansas and spread through the transport of American soldiers to Europe to fight in the First World War. Later, it traveled to British colonies in India and Africa via the transport of British troops, and the result was the rise of independence movements in these countries. 1980s: HIV/AIDS The HIV/AIDS crisis caused hysteria surrounding gay men. 2014: Ebola Another event that sparked hysteria was the recent outbreak of Ebola in West Africa. The governors of New York and New Jersey threatened to close their airports, though there was little chance of the virus breaking out in the United States. (To the best of Fr. Ryan's knowledge, only two Americans developed the disease.)






