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Novel coronavirus discovered in British bats featured image

Novel coronavirus discovered in British bats

A coronavirus related to the virus that causes Covid-19 in humans has been found in UK horseshoe bats – according to new collaborative research from the University of East Anglia, ZSL (Zoological Society of London), and Public Health England (PHE). However, there is no evidence that this novel virus has been transmitted to humans, or that it could in future, unless it mutates. UEA researchers collected faecal samples from more than 50 lesser horseshoe bats in Somerset, Gloucestershire and Wales and sent them for viral analysis at Public Health England. Genome sequencing found a novel coronavirus in one of the bat samples, which the team have named ‘RhGB01’. Due to the rapid response nature of this research, it has not yet been peer reviewed. It is the first time that a sarbecovirus (SARS-related coronavirus) has been found in a lesser horseshoe bat and the first to be discovered in the UK. The research team say that these bats will almost certainly have harboured the virus for a very long time. And it has been found now, because this is the first time that they have been tested. Importantly, this novel virus is unlikely to pose a direct risk to humans, unless it mutates. A mutation could happen if a human infected with Covid-19 passes it to an infected bat, so anyone coming into contact with bats or their droppings, for example those engaged in caving or bat protection, should wear appropriate PPE. Prof Diana Bell, an expert in emerging zoonotic diseases from UEA’s School of Biological Sciences, said: “Horseshoe bats are found across Europe, Africa, Asia and Australia and the bats we tested lie at the western extreme of their range. “Similar viruses have been found in other horseshoe bat species in China, South East Asia and Eastern Europe. “Our research extends both the geographic and species ranges of these types of viruses and suggests their more widespread presence across more than 90 species of horseshoe bats. “These bats will almost certainly have harboured this virus for a very long time – probably many thousands of years. We didn’t know about it before because this is the first time that such tests have been carried out in UK bats. “We already know that there are different coronaviruses in many other mammal species too,” she said. “This is a case of ‘seek and you will find’. “Research into the origins of SARS-CoV-2, the virus that causes Covid-19 in humans, has focussed on horseshoe bats - but there are some 1,400 other bat species and they comprise 20 per cent of known mammals. “Our findings highlight the need for robust genotype testing for these types of viruses in bat populations around the world. And it raises an important question about what other animals carry these types of viruses.” Prof Andrew Cunningham, from the Zoological Society of London, said: “Our findings highlight that the natural distribution of sarbecoviruses and opportunities for recombination through intermediate host co-infection have been underestimated. “This UK virus is not a threat to humans because the receptor binding domain (RBD) – the part of the virus that attaches to host cells to infect them - is not compatible with being able to infect human cells. “But the problem is that any bat harbouring a SARS-like coronavirus can act as a melting pot for virus mutation. So if a bat with the RhGB01 infection we found were to become infected with SARS-CoV-2, there is a risk that these viruses would hybridise and a new virus emerge with the RBD of SARS-CoV-2, and so be able to infect people. “Preventing transmission of SARS-CoV-2 from humans to bats, and hence reducing opportunities for virus mutation, is critical with the current global mass vaccination campaign against this virus.” Prof Bell added: “The main risks would be for example a bat rehabilitator looking after a rescued animal and infecting it with SARS-CoV2 - which would provide an opportunity for genetic recombination if it is already carrying another sarbecovirus. “Anyone coming into contact with bats or their droppings, such as bat rescuers or cavers, should wear appropriate PPE – in order to reduce the risk of a mutation occurring. “We need to apply stringent regulations globally for anyone handling bats and other wild animals,” she added. The new virus falls within the subgroup of coronaviruses called sarbecoviruses which contains both SARS-CoV-2 (responsible for the current pandemic) and SARS-CoV (responsible for the initial 2003 SARS outbreak in humans). Further analysis compared the virus with those found in other horseshoe bat species in China, South East Asia and Europe and showed that its closest relative was discovered in a Blasius’s bat from Bulgaria in 2008. Ivana’s story The UK discovery was made by undergraduate ecology student Ivana Murphy, from UEA’s School of Biological Sciences, who collected bat droppings as part of her final year research dissertation. Jack Crook conducted the genetic analyses in partnership with other researchers at PHE. A total of 53 bats were captured, and their faeces collected in sterile bags. The research was conducted under strict Health and Safety protocols. Full PPE was worn and Ivana was regularly tested for Covid-19 to avoid any chance of cross contamination. The bats were released immediately after their droppings had been collected. Ivana said: “I am very fortunate to be surrounded by so many experts in their fields, which has allowed me access to resources that many undergraduates wouldn’t have. I feel extremely lucky to have been able to conduct such an advanced study.” “We weren’t shocked by the results, but I am extremely eager to carry out further research. “I chose to study ecology at UEA as I have a passion for trying to protect and conserve nature. I wanted a better understanding of the global situation and so chose UEA to study ecology and conservation. “The plan after graduation is to do an extended study of viruses in UK bats, very similar to the one I carried out as an undergraduate. There is still a lot more to understand and I am extremely excited to see what else we can find out.” But she says that she doesn’t want her research to turn people against bats. “More than anything, I’m worried that people may suddenly start fearing and persecuting bats, which is the last thing I would want and would be unnecessary. As like all wildlife, if left alone they do not pose any threat.” ‘Metagenomic identification of a new sarbecovirus from horseshoe bats in Europe’ is published on the Research Square pre-print server. Read the full story, including a Q&A with all you need to know.

5 min. read
Smell training, not steroids, best treatment for Covid-19 smell loss featured image

Smell training, not steroids, best treatment for Covid-19 smell loss

Steroids should not be used to treat smell loss caused by Covid-19 according to an international group of smell experts, including Prof Carl Philpott from the University of East Anglia. Smell loss is a prominent symptom of Covid-19, and the pandemic is leaving many people with long-term smell loss. But a new study published today shows that corticosteroids - a class of drug that lowers inflammation in the body – are not recommended to treat smell loss due to Covid-19. Instead, the team recommend ‘smell training’ – a process that involves sniffing at least four different odours twice a day for several months. Smell loss expert Prof Carl Philpott from UEA’s Norwich Medical School, said: “The huge rise in smell loss caused by Covid-19 has created an unprecedented worldwide demand for treatment. “Around one in five people who experience smell loss as a result of Covid-19 report that their sense of smell has not returned to normal eight weeks after falling ill. “Corticosteroids are a class of drug that lowers inflammation in the body. Doctors often prescribe them to help treat conditions such as asthma, and they have been considered as a therapeutic option for smell loss caused by Covid-19. “But they have well-known potential side effects including fluid retention, high blood pressure, and problems with mood swings and behaviour.” The team carried out a systematic evidence-based review to see whether corticosteroids could help people regain their sense of smell. Prof Philpott said: “What we found that there is very little evidence that corticosteroids will help with smell loss. And because they have well known potential adverse side effects, our advice is that they should not be prescribed as a treatment for post-viral smell loss. "There might be a case for using oral corticosteroids to eliminate the possibility of another cause for smell loss actually being a confounding factor, for example chronic sinusitis – this is obviously more of a diagnostic role than as a treatment for viral smell loss. “Luckily most people who experience smell loss as a result of Covid-19 will regain their sense of smell spontaneously. Research shows that 90 per cent of people will have fully recovered their sense of smell after six months. “But we do know that smell training could be helpful. This involves sniffing at least four different odours twice a day every day for several months. It has emerged as a cheap, simple and side-effect free treatment option for various causes of smell loss, including Covid-19. “It aims to help recovery based on neuroplasticity - the brain’s ability to reorganise itself to compensate for a change or injury,” he added. The research was led by researchers at the Cliniques universitaires Saint-Luc in Brussels (Belgium) in collaboration with the Univeristé catholique de Louvain, Brussels (Belgium), the University of East Anglia (UK), Biruni University, Istanbul (Turkey), Aarhus University (Denmark), Université du Québec à Trois-Rivières (Canada), Geneve University Hospitals (Switzerland), Harvard University (USA), Aristotle University, Thessaloniki (Greece), University of Insubriae (Italy), University of Vienna (Austria), the University of Chicago (USA) and the University of Colorado (USA). ‘Systemic corticosteroids in COVID-19 related smell dysfunction: an international view’ is published in the journal International Forum of Allergy & Rhinology.

3 min. read
COVID expert: Prof Lawrence Young, UK featured image

COVID expert: Prof Lawrence Young, UK

Professor Lawrence Young of the University of Warwick is one of the go-to experts in the UK on COVID-19. A Professor of Molecular Oncology at Warwick Medical School, he can comment on many aspects of the pandemic -- from the nature of the virus itself and its effects in patients, to its impacts on hospitals and wider society. He regularly features on TV, radio, and newspapers in the UK and worldwide, including: If you would like to book an interview with Prof. Young, contact press@warwick.ac.uk or L.Walton.1@warwick.ac.uk 

1 min. read
A Season of Resiliency featured image

A Season of Resiliency

Spring 2021 begins a season of resiliency. After a long and particularly snowy winter in New York, I look forward to welcoming my favorite cherry blossoms. It’s been a year now since the COVID shutdowns took hold and the pandemic pause has required enormous energy from all of us at Japan Society, from remote work with constant online meetings, to safeguarding our 50-year-old building, to pivoting to online programming and finding new ways to bring in revenue. It’s not really been a “pause” in the traditional sense, it’s been a race for organizational transformation, adaptation to new ways of communicating with our colleagues and our members, and now — a reopening! This spring, we are delighted to celebrate our reopening with When Practice Becomes Form: Carpentry Tools from Japan, a special exhibition that explores the extraordinary, centuries-long tradition of Japanese architecture and woodworking artistry, and features a range of hand tools and models that reflect techniques used for hundreds of years to build and restore Japan’s wooden architectural masterpieces — temples, shrines, and bridges. Philosophy of Japanese woodworking The philosophy that undergirds Japanese woodworking is deeply engrained in Japan Society’s own history. As master woodworker George Nakashima wrote in his book, The Soul of a Tree, “We can walk in step with a tree to release the joy in her grains, to join with her to realize her potentials, to enhance the environments of man.” Fifty years ago, Junzo Yoshimura, the architect of Japan Society’s now-landmarked building, asked that Japanese hinoki cedar be used for the coffered ceilings in the Society’s lobby and selected with his own hands stones to be shipped from Japan for the foyer garden. He also specified furniture to be crafted by Nakashima in his New Hope, Pennsylvania workshop, furniture that has stood the test of time and is still in use today. Precision is a hallmark of the Japanese experience. One of the many ways to view this is through the concept of kodawari — a unique Japanese notion that is difficult to translate — referring to the uncompromising, relentless devotion to one’s art, pursuit, profession, or activity. In a world turned upside down by a pandemic, there has never been a more welcome time to explore this relentless pursuit of precision and quality in one’s work at all levels of kodawari — in the form of Japanese woodworking. Tools of leadership, alliance & innovation The resilient spirit of Japanese craftsmanship resonates, especially in these unusual times. The presence of tools in our galleries and an exploration of their longstanding heritage for a broad audience highlights the persistent strength of U.S.-Japan relations and human ingenuity. As a leader, I take my own inspiration from Nakashima, using the strength of the oak tree in the West and flexibility of bamboo in the East to bring out the strength, resiliency, and innovation of the U.S.-Japan alliance through my own set of tools. These are the tools of leadership, which require the knowledge and precision of a master carpenter, building for the present while planning for the future. As Nakashima writes, “Each cut requires judgments and decisions on what the log should become.” In kigumi — traditional Japanese wooden joinery — each part plays a crucial role since the joints are fitted together without any nails or fasteners. To have structural integrity, the work — whether furniture or architecture — needs to be weight bearing, and with its direct connections, the whole will ultimately be stronger than its separate elements. In an ongoing cycle of repair and renewal, old joints are replaced by new ones, allowing traditional Japanese buildings to stand for hundreds of years. I find a parallel in the U.S.-Japan alliance, where our direct connection is the strength of our relationship — a collective strength where each nation can accomplish more together. Fifty years ago, as Japan Society’s new building was preparing to open to the public, Deputy Executive Director Daniel J. Meloy wrote to George Nakashima: “Your first shipment to us arrived safely today with all pieces in good shape. We have unwrapped them, dusted them, carried them to their respective rooms, and we love them.” This spring, I invite you to visit When Practice Becomes Form, and help us celebrate our reopening. Let’s work together, using the tools of tradition and innovation, to build the next 50 years of our alliance. Given the challenges the world has faced this past year, the U.S.-Japan alliance has never been more necessary — as acknowledged by the fact that the first world leader to visit President Biden’s White House will be Japanese Prime Minister Yoshihide Suga. The personification of the importance of this relationship through this visit, along with the elevation of the “Quad” meeting between the leaders of Australia, India, Japan, and the United States, indicates a new emphasis in American foreign policy. In addition to the geopolitical challenges confronting our nations, Americans have been struggling domestically with the rise in anti-Asian hate crimes and harassment — a powerful reminder of critical battles still to be fought at home. The Japanese American experience, including forced relocation to internment camps during World War II and the 1980s discrimination triggered by economic tensions with Japan, are only two examples of the long history of anti-Asian racism we continue to confront as a country and community. Now, more than ever, we must bring our collective strength to bear to fight hate and bigotry — and build a stronger and more resilient society. Joshua Walker (@drjwalk) is president and CEO of Japan Society. Follow @japansociety. The views expressed in this article are the writer’s own.

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4 min. read
Are We Over-Sanitizing? featured image

Are We Over-Sanitizing?

The days of wiping down groceries may be coming to an end, but will Americans' reliance on hand sanitizer follow suit? This week, the Centers for Disease Control and Prevention (CDC) released a report confirming that the risk of catching the coronavirus from surfaces is low. Kevin Minbiole, PhD, chair of the Department of Chemistry at Villanova University, weighs in on hand sanitizer use—and whether too much sanitizing is a bad thing. "I think that a lot of the concern on the overuse of hand sanitizer a decade ago or so was the overuse of triclosan, a strong antimicrobial agent that would persist in wastewater," said Dr. Minbiole, referring to a theory that arose following the H1N1 pandemic in 2009. At that time, scientists expressed worry that bacteria were becoming resistant to hand sanitizer. "It seemed like overkill to go beyond soap and water or simply ethanol (alcohol)—or to add triclosan into hand soap," Dr. Minbiole continued. While Dr. Minbiole does not dismiss this theory, he notes, "I believe there was merit to the concerns of overapplying antibiotics and antiseptics when they were not needed." Looking to the future, Dr. Minbiole does not see hand sanitizer playing as big a role. "I don't foresee a backlash so much here, as folks recognize that this particular virus is more of an airborne concern," he says.

1 min. read
St. Georges Technical High School is first high school in the U.S. to use the Gene Editing Institute’s CRISPR in a Box Educational Toolkit™ featured image

St. Georges Technical High School is first high school in the U.S. to use the Gene Editing Institute’s CRISPR in a Box Educational Toolkit™

Toolkit is easily incorporated into any laboratory science course Wilmington, Del., April 1, 2021 – St. Georges Technical High School in southern New Castle County, Delaware is the first high school in the United States to use ChristianaCare Gene Editing Institute’s innovative CRISPR in a Box Educational Toolkit™ in a science class. CRISPR in a Box brings to life the much-heralded CRISPR gene editing technology – the “genetic scissors” that allow scientists to edit DNA. The toolkit is designed for educational sessions in secondary and post-secondary schools and is suitable for remote learning. “Gene editing is the future of medicine,” said Eric Kmiec, Ph.D., director of ChristianaCare’s Gene Editing Institute. “Our partnership with the Delaware Department of Education will help cultivate the next generation of genetic scientists and enhance Delaware’s position as a leader in the biosciences.” “We are thrilled that students at St. Georges Technical High School will be the first In the United States to experience a live demonstration of CRISPR gene editing using our Innovative CRISPR in a Box educational toolkit,” said Siobhan Hawthorne, Education and Community Outreach leader at ChristianaCare’s Gene Editing Institute. “This toolkit will provide STEM students with a visual understanding of how the exciting CRISPR technology can unlock medical treatments to improve lives.” Delaware Secretary of Education Susan Bunting praised her department's partnership with ChristianaCare's Gene Editing Institute to develop the “Seeds of STEM” course that teaches high school students about gene editing. “Gene editing approaches diseases in new ways and will have significant impact in the health care and agriscience fields,” Bunting said. “This is a great example of an industry and education partnership investing in youth by providing hands-on knowledge and skills around emerging technology.” “We are so fortunate that ChristianaCare’s Gene Editing Institute reached out to our program to plan a high school ‘first’ opportunity with this new CRISPR experiment,” said Danya Espadas, one of the St. Georges biotech teachers. “Giving students the chance to use a cutting-edge, 21st century tool for medicine in their own high school lab – to have that technology at their fingertips – transcends what they see in a textbook or a video. By being able to do it themselves, it makes it real for them.” Espada said the experiment focuses on editing a gene of a non-infectious E.coli bacteria to become resistant to an antibiotic, thereby allowing researchers to create a new class of antibiotics that cannot be overcome by bacteria that are gene resistant. “We’re talking about eventually saving lives, here,” she said. “What can be more important than that?” The tools in CRISPR in a Box have been designed based on the pioneering discoveries of the Gene Editing Institute that are currently being used to explore next-generation medical therapies and diagnostics for diseases, including lung cancer and sickle-cell anemia. Component items in the toolkit include the CRISPR/Cas complex, a target DNA molecule, a mammalian cell free extract and a synthetic DNA molecule. All materials in the kit are safe, synthetic materials. There are no live cultures or viruses involved. The kit is meant to provide a hands-on demonstration of CRISPR’s capabilities, and not allow for manipulations of living organisms. “The kit is easy and fun to use,” said Kristen Pisarcik, research assistant at the Gene Editing Institute who has taught students at Delaware Technical Community College which first used the toolkit. “In a short period of time students will reliably and successfully complete the laboratory activity and be able to see the results of gene editing,” she said. Since the foundations of the kit touch upon key themes in biology, it can be readily incorporated into practically any science or biology course with a laboratory component, “One of the beauties of CRISPR in a Box is that there is no need to purchase specialized equipment. If a teaching lab can support bacterial cultivation, it can perform the in vitro gene editing lab activity,” Pisarcik said. CRISPR in a Box is the evolution of a partnership between the Gene Editing Institute, Delaware Technical Community College and Rockland Immunochemicals that began in 2017 with a National Science Foundation grant to develop the first-ever gene editing curriculum for community college students. Video and photo collection of first class in U.S. to use CRISPR in a Box™ educational gene editing toolkit. About ChristianaCare’s Gene Editing Institute The Gene Editing Institute, a worldwide leader in CRISPR gene editing technology and the only institute of its kind based within a community health care system, takes a patient-first approach in all its research to improve the lives of people with life-threatening disease. Since 2015, researchers at the Gene Editing Institute have been involved in several ground-breaking firsts in the field, including the development of the first CRISPR gene editing tool to allow DNA repairs outside the human cell which will rapidly speed therapies to patients and a unique version of CRISPR called EXACT that reduces the number of off-target edits to other areas of the genome, which is vital for further research and patient applications. Its researchers are currently developing a patient trial for lung cancer using CRISPR and employing the technology to combat the COVID-19 pandemic. About the biotech program St. Georges Technical High School The Biotech career program of study at St. Georges Technical High School is the first such program offered in a Delaware high school. With two teachers and approximately 100 students in grades 10-12, the program presents advanced content in biology and chemistry with opportunities for students to learn basic laboratory techniques and procedures and to maintain and operate common instruments and equipment used in a biotechnology laboratory. St. Georges is a comprehensive career and technical high school with 1,100 students who study in one of 16 different career pathways.

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4 min. read
Public health education soars in wake of pandemic  featured image

Public health education soars in wake of pandemic

Maybe a silver lining can be found from the COVID-19 pandemic, as interest in public health education is soaring at U.S. colleges and universities, says a nationally prominent public health professor. Public health education has become a logical choice for students when looking at changing public health practice trends and their implications for public health education, explained Gulzar Shah, Ph.D., who authored an invited editorial in the March issue of the American Journal of Public Health (AJPH). Shah is department chair and professor of health policy and community health in Georgia Southern University’s Jiann-Ping Hsu College of Public Health. His editorial is titled “Public Health Education and Changing Public Health Realities in the Public Health 3.0 Era.” “For many of the 19 million college students enrolling annually in public and private colleges in the United States, public health is becoming a logical choice,” he said. “Because of COVID-19, interest in public health careers is soaring, evident from the 20% increase nationwide in Master of Public Health applicants.” The editorial also drew insights from the Association of Schools and Programs of Public Health’s national-level data from schools and programs of public health about the first employment destinations of public health graduates. “The emphasis on aligning public health practice and policy with the Public Health 3.0 framework, in which leaders partner across various sectors to address social, environmental and economic factors that affect population health and health inequity, has attracted the spotlight on generalist, behavioral education and health policy degrees,” Shah noted. “The Public Health 3.0 framework has also underscored the desirability of adopting the Health in All Policies approach and encouraging public health leaders to act as chief health strategists in influencing policies in other sectors affecting population health. Increasing focus on Health in All Policies and higher salary positions in health care may further explain the popularity of health policy and management and health law programs.” If you are a journalist looking to know more about Dr. Shah’s work, and the importance public health education in America of the programs Georgia Southern is offering – then let us help. Dr. Gulzar H. Shah is a Professor and Department Chair, Health Policy and Community Health at the Jiann-Ping Hsu College of Public Health (JPHCOPH), Georgia Southern University. He is available to speak with media regarding this important topic - simply click on his icon now to arrange an interview today.

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2 min. read
The Zoom Boom? More and more Americans are getting plastic surgery – let our expert explain why featured image

The Zoom Boom? More and more Americans are getting plastic surgery – let our expert explain why

After almost a year where most American offices went unused, experts are noticing an unexpected side effect from all those online meetings. It appears that prolonged exposure to seeing yourself in that tiny box during video calls is inspiring a sudden uptick in plastic surgery. The plastic surgery industry is booming during the coronavirus pandemic, largely due to the increase in the number of virtual meetings offered through Zoom and other video web services. Call it the “Zoom boom.” The interest in cosmetic surgery is boosting appointments for Botox, lip fillers and other plastic surgery procedures that help people feel more attractive on computer screens, according to Dr. Maria Helena Lima, an assistant professor of Surgery for the Section of Plastic and Reconstructive Surgery in the Medical College of Georgia at Augusta University. “In the last few months, there has been a jump in the number of patients wanting plastic surgery procedures,” said Lima. “We have discovered that when people are in Zoom meetings, they should be listening to the content and paying attention to what’s going on, but they’re not.” Lima says participants are oftentimes looking at themselves on the screen and wondering what could be done to alter their image. It is a trend that offers up some interesting questions: • Along with the Zoom boom, are there other reasons people are opting to go under the knife for an elective procedure? • Are there long-term consequences to these decisions? • What do patients need to know first to avoid any safety or health issues? There’s a lot to know about this topic, and if you are a journalist looking to learn more, then let us help with your coverage. Dr. Maria Helena Lima is one of the nation’s leading plastic surgeons with 12 years of experience specializing in aesthetic plastic surgery, facial reconstruction and craniofacial pediatric plastic surgery. She is available to speak with media about this emerging trend. Simply click on her name now to arrange an interview today.

2 min. read
The aftermath of a mass shooting in America featured image

The aftermath of a mass shooting in America

Last week America was shocked by two major mass shooting events in a week. Almost 20 people were killed and so many more will suffer the short- and long-term effects of these tragic and violent events. According to recent media reports, though the election and a full year of COVID-19 dominated news coverage, 2020 was one of the deadliest years for gun violence in decades. Until two lethal rampages this month, mass shootings had largely been absent from headlines during the coronavirus pandemic. But people were still dying — at a record rate. In 2020, gun violence killed nearly 20,000 Americans, according to data from the Gun Violence Archive, more than any other year in at least two decades. An additional 24,000 people died by suicide with a gun. The vast majority of these tragedies happen far from the glare of the national spotlight, unfolding instead in homes or on city streets and — like the Covid-19 crisis — disproportionately affecting communities of color. March 23, Washington Post And as America carries on and moves forward, the survivors, witnesses and families of those killed will be adapting to a new life and a multitude of physical and psychological challenges. If you’re a reporter looking to cover the issues survivors of mass-shooting events will experience, then let us help. Dr. Laura C. Wilson is a clinical psychologist whose expertise focuses on post-trauma functioning, particularly in survivors of sexual violence or mass trauma (e.g., terrorism, mass shootings, combat). Her research interests extend to predictors of violence and aggression, including psychophysiological and personality factors, as well as indicators of PTSD following mass trauma, long-term functioning among first responders, outcomes among survivors of sexual violence, and the influence of media on mental illness stigma. Dr. Wilson is available to speak with media – simply click on her icon to arrange an interview today.

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2 min. read
What Can A Forgotten Piece of Our Opioid Addiction and Treatment History Teach Us? featured image

What Can A Forgotten Piece of Our Opioid Addiction and Treatment History Teach Us?

As the nation struggles with the third wave of a continuing opioid epidemic, a newly republished book co-authored by Nancy Campbell, the head of the Department of Science and Technology Studies at Rensselaer Polytechnic Institute, offers insight into present-day drug addiction and treatment by exploring a complex chapter from the nation’s past. Written with JP Olsen and Luke Walden, The Narcotic Farm: The Rise and Fall of America’s First Prison for Drug Addicts details the history of the United States Narcotic Farm, a federal institution that opened in 1935 outside of Lexington, Kentucky. Jointly operated from 1935 to 1975 by the U.S. Public Health Service and the Federal Bureau of Prisons, the Narcotic Farm was a combination prison, hospital, working farm, rehabilitation center, and research laboratory. “All of our scientific knowledge about human opioid addiction comes from that time, comes from that place,” said Campbell, a leading figure in the social history of drugs, drug policy, and harm reduction, on an episode of the Landmark Recovery Radio podcast. The facility, which was also the subject of a 2009 documentary featuring Campbell, has a complicated legacy. It revolutionized treatment methods commonly accepted today, such as using methadone to medically manage heroin detox and the development of drugs like naloxone and buprenorphine. But it fell under a cloud of suspicion in 1975, when Congress learned that researchers had recruited patients as test subjects for CIA-funded LSD experiments as part of the notorious MK-Ultra project. “With the ongoing opioid epidemic worsening this past year in the midst of the COVID-19 pandemic, the lessons learned in this book continue to be relevant today,” Campbell said. Campbell is also the author of Using Women: Gender, Drug Policy, and Social Justice and Discovering Addiction: The Science and Politics of Substance Abuse Research, as well as the co-author of Gendering Addiction: The Politics of Drug Treatment in a Neurochemical World. Her most recent book, OD: Naloxone and the Politics of Overdose, was published in 2020. “Nobody should die of overdose. A high overdose death rate signals that we have not cared for the people who have been hurt most by the war on drugs, first pursued by President Dwight D. Eisenhower in 1954,” Campbell said in a recent “Academic Minute” segment. Campbell is available to discuss a wide range of topics relating to drug policy and history, including the Narcotic Farm.

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2 min. read