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ChristianaCare Earns Third Consecutive Apex Recognition Award for Excellence in Respiratory Care
ChristianaCare one of only nine health systems to receive the honor for three consecutive terms For exceptional care in ensuring patients are able to easily breathe during their hospital stay, ChristianaCare has earned its third consecutive Apex Award in the Acute Hospital category. Conferred by the American Association for Respiratory Care (AARC), the award recognizes ChristianaCare for its “exemplary demonstration of best practices in respiratory care.” ChristianaCare is one of only 18 health systems nationwide to earn this award and one of just nine to receive the honor for at least three consecutive terms. As a key component of hospital care, respiratory care is an important contributor to the overall quality and safety of a hospital. For patients and their families, ChristianaCare’s continuing recognition in this category is further reassurance that the health system’s quality is among the best in the nation. “At ChristianaCare, we commit to being exceptional today and even better tomorrow,” said John S. Emberger, BS, RRT-AACS, FAARC, CPHQ, director of Respiratory Care at ChristianaCare. “This recognition belongs to all the respiratory therapists on our team. They are committed to following evidence-based practices and to ensuring that every action they take is safe. It’s a deep privilege to lead a team so committed to our organization’s core values of love and excellence.” ChristianaCare’s respiratory team comprises nearly 150 caregivers who provide respiratory care within hospitals and outpatient settings and manage the mechanical ventilators and artificial airways used to help ICU patients breathe. To support continuous improvement, the team rigorously measures and tracks quality, patient satisfaction, safety and operational performance. That work has made an impact that extends beyond ChristianaCare; for example, the respiratory team’s success in standardizing practices to reduce infections and inflammations that can occur in patients on ventilators was published in the peer-reviewed journal Respiratory Care. Another key ingredient to the team’s success has been its ability to attract and retain top talent. ChristianaCare’s respiratory department is set up with clinical career ladders that provide the opportunity for caregivers to broaden their skills and responsibilities through their participation in quality improvement projects. “Our respiratory therapists are always seeking ways to improve and grow,” said Michael Benninghoff, DO, MS, section chief for Medical Critical Care, and the medical director of respiratory care at ChristianaCare. “They have played a significant role in helping our ICUs achieve excellent outcomes in caring for many of our sickest patients. They measure their performance and continuously look for ways to innovate.” The Apex Recognition Award was developed in 2017 as a way for the AARC to recognize respiratory care departments that demonstrate high quality care. “Respiratory care departments dedicate themselves to delivering excellent care for patients everywhere. They are a vital component to a patient’s care team, making a positive impact for the quality of patient care,” said AARC President Carl Hinkson, MSc, RRT, RRT-ACCS, RRT-NPS, FAARC. “Earning the Apex Recognition award is a tremendous honor. It shows how these teams reach high standards and bring their specialized skills to their health care colleagues. Congratulations to ChristianaCare as one of our 2023-2024 Apex Recognition Award recipients.”

Researchers find an association between autistic traits and young children with ear, nose and throat problems The study used data from the Children of the 90s study which found 177 children were identified with a probable diagnosis of autism – 139 boys and 38 girls The study looked at data from over 10,000 children from birth to four years old. Ear, nose and throat (ENT) problems, relating to the ears, hearing and the upper respiratory system, are more common in young children with a subsequent diagnosis of autism, or who have demonstrated high levels of autism traits - finds new research published in BMJ Open. The study, which was led by researchers from the University of Bristol and Aston University, looked at data from over 10,000 young children from birth to four years old, who were part of the Bristol’s Children of the 90s study. The team investigated whether early ear and upper respiratory signs are associated with the development of autistic traits. Previous studies have found increased prevalence of ENT and related hearing conditions in children with autism compared with typically developing children, but much of this research has been carried out using health records, which can be biased. In the new study, researchers used data from Children of the 90s study, a general population cohort which recruited over 14,000 pregnant women from the Bristol area between 1991 and 1992 and has followed the lives of their offspring ever since. Within Children of the 90s, 177 children were identified with a probable diagnosis of autism – 139 boys and 38 girls. Those with autism traits were defined as the 10% of the sample with the highest trait scores. The team analysed responses to three questionnaires in which mothers recorded the frequency of nine different signs and symptoms relating to the ears, hearing problems and upper respiratory system when their child was aged 18 to 42 months. These included signs such as mouth breathing, snoring, pulling/poking of the ears, ears going red, worse hearing during a cold, ear discharge and rarely listening. The results found that the frequency of these symptoms was associated with high scores on each of the autism traits: social communication, coherent speech, sociability and repetitive behaviours, plus those with a clinical diagnosis of autism. Pus or sticky mucus discharge from the ears was especially associated with autism (an increased risk of 3.29) and for impaired hearing during a cold (an increased risk of 2.18). Dr Amanda Hall, senior lecturer in audiology, at Aston University, said: “Thanks to the data available from Children of the 90s, we were able to analyse results from a large number of children. We found that common ear and upper respiratory signs and symptoms appear to be more prevalent in those with a subsequent diagnosis of autism or demonstrated high levels of autism traits. “However it is also important to note that these ENT symptoms are very common in childhood and most children who experience these signs and symptoms do not go on to be diagnosed with autism. “For example, of the group of around 1,700 children who snored at age 30 months, most of those 1,660 children did not get a later diagnosis of autism. Our results suggest the need for increased awareness of possible ENT conditions.”

UF astrobiologist partakes in her second NASA mission to Mars
By Halle Burton NASA’s Mars Perseverance rover mission is no easy task, yet its distinguished team has discovered signs of organic molecules, containing chemicals known for making life possible on Earth. One of these long-term planners is University of Florida astrobiologist, Amy Williams. “Organics make up life as we know it,” Williams said. “Seeing organic carbon on Mars sets us up to understand if the building blocks for life were present on the planet in the past through the lens of how life evolved on Earth.” Williams and the Perseverance team were published in November’s Science magazine for their organic molecules analysis, after finding numerous organic carbons on the Jerezo crater floor. Through NASA’s Jet Propulsion Laboratory, Perseverance is studying the crater with collected rock samples planned to be sent to Earth during the Mars Sample Return mission. Upon further research and testing on Earth, these rocks could determine compelling evidence of past life on Mars. Several of the rock samples indicate altercations by water, making scientists propose that a water-infused Mars could have supported ancient life. The Jerezo crater itself serves as an intriguing site to study past life on the terrestrial planet. The creation of the crater implies Mars contained a primitive river streaming into a lake billions of years ago. Now, Williams is no stranger to working with the detection of organic molecules on Mars. In 2015, she worked with the Curiosity rover which also found organic carbon on the inner planet. With her work diversified on the Perseverance team, evidence is closer than ever to proving the omnipresence of organic carbon on Mars. “Seeing a consistent story is always reassuring as a scientist,” Williams said.

Is there a link between CTE and mass shootings? Let our expert explain
This spring news of mass shootings has dominated the headlines almost weekly with stories of tragedy in Michigan, Tennessee, Kentucky and Alabama. To date, there have been an estimated 160 mass-shootings in America this year. In the wake of each tragedy, Americans are left asking 'How this could happen?' and 'Why did this happen?' In the case of the April 10 shooting in Louisville, the parents of the gunman are also seeking answers as they claim prior trauma and CTE may have played some part in the shooter's actions and motivation. It's a theory that's getting a lot of attention from doctors and journalists. The family of Connor Sturgeon – who was killed after he fatally shot five people Monday morning at the Old National Bank in Louisville, Kentucky – plans to have his brain tested for chronic traumatic encephalopathy, commonly known as CTE, his father and a spokesperson for the family told CNN on Thursday. “Yes, Connor is being tested for CTE. Probably will take a while to get results,” Todd Sturgeon, Connor Sturgeon’s father, texted to CNN. Pete Palmer, a family friend who is speaking for the Sturgeons, said the family and the state medical examiner are looking to have Connor Sturgeon’s brain tested. April 14 - CNN There's a lot to know when reporting on CTE, especially when it involves the potential links to tragedy and a mass shooting. And that's where clinical experts can help and make sure reporters have the details, terminology and facts correct when covering such important topics. With over 40 years of clinical practice, Wayne Hulon is an American Board Certified Psychotherapist, and is also recognized by the State of Georgia as a Licensed Professional Counselor. In addition to his private practice, Wayne serves as a member of the American College of Psychotherapy and is currently serving as its Executive Director. Wayne is available to speak with media regarding this subject - simply click on his icon now to arrange an interview today.

Gene Editing Institute Opens a Unique Learning Lab for High School and College Students
Free program uses CRISPR in a Box™ toolkit to teach the power of gene editing To inspire the next generation of students to pursue careers in STEM (science, technology, engineering and math) and learn about the power of genomic science, ChristianaCare’s Gene Editing Institute has launched a new Learning Lab on its premises that offers educational programming about revolutionary CRISPR gene editing technology. Located next to the Gene Editing Institute’s lab on the University of Delaware’s STAR Campus, the Learning Lab is a physical space that provides an immersive field trip experience for upper-level high school students and college undergraduates who may not have access at their schools to a laboratory to conduct gene editing experiments. There is no cost for schools to use the lab or for the materials to conduct the experiment. The Gene Editing Institute wants to ensure that all schools have equal opportunity to participate in educational programming at the lab. Students using the lab can perform a gene editing experiment in a single day using the Gene Editing Institute’s innovative CRISPR in a Box™ educational toolkit. All materials in the kit are safe, synthetic materials, and allow students to perform CRISPR gene editing with non-infectious E. coli bacteria. They will be able to see an appearance change indicating gene editing has occurred at the end of their experiment. “Students around the country, no matter where they go to school, have the potential to be scientists, researchers and laboratory technicians,” said Eric Kmiec, Ph.D., executive director and chief scientific officer of ChristianaCare’s Gene Editing Institute. “Our hope is that by creating access and space for students to explore, we can inspire the next generation of students to pursue STEM careers. The Learning Lab allows us to help cultivate the next generation of genetic scientists and strengthen Delaware and our region as a leader in biotechnology.” Education Program Manager Amanda Hewes, MS, developed the Learning Lab after noticing a problem that was undercutting the opportunities of teachers to bring gene editing experiments into the classroom — a lack of space and equipment. Amanda Hewes, education program coordinator, assists students from Wilmington Charter School with their samples of DNA during a Learning Lab experiment. “We don’t want anything to hinder the way students learn about CRISPR gene editing,” Hewes said. “If a student feels like there are too many steps, or a teacher doesn’t have an essential piece of equipment, then we’ve lost an opportunity to bring the next generation of scientists into the lab. We’re striving to break down as many barriers as possible for students.” Learning real-world applications of gene editing The Learning Lab also allows students to speak directly with experts in the field about careers in biotechnology and gene editing as they learn the difference between such things as phenotypic and genotypic readouts in their gene editing experiments. This gives students the chance to ask about the real-world application of genome experiments in a research lab. It also lets them think about their place in a lab setting. “I’ve never been in an actual lab setting before,” said Shiloh Lee, a junior at the Charter School of Wilmington, at a recent class. “I think it is very, very cool to be able to experience it.” “I’ve learned a lot of new skills with the micropipetting,” said Pauline Zhuang, a senior at The Charter School of Wilmington. “We don’t have the same resources at our school. The CRISPR in a Box is such a great resource. My classmates and I have been able to experience, firsthand, what it is like to actually do gene editing.” Through the program, the Gene Editing Institute hopes to educate 1,000 students by spring 2024. Currently, the lab is on track to engage more than 200 students by the end of the spring 2023 semester. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats, which are the hallmark of a bacterial defense system that forms the basis for CRISPR-Cas 9 genome editing technology. The CRISPR technology enables researchers to modify genes in living cells and organisms and may make it possible to correct mutations at precise locations in the human genome in order to treat genetic causes of disease. For more information about the Learning Lab and the educational program, email geneeditinginstitute@christianacare.org.

As technology continues to advance, so do the methods that hackers use to steal personal information. One such method that even the FBI has taken notice of is juice jacking, a technique where hackers use public charging stations to install malware onto your device or steal your personal information. The specific danger is very real, experts say. Steve Weldon, director of the Cyber Institute at Augusta University’s School of Computer and Cyber Sciences, said people need to understand there is risk when plugging a phone into a USB port at a public charging station. “USB uses pins for data and power. When we plug devices in to charge, the data pins are also connected,” said Weldon. “No big deal if we’re in an environment we trust. However, do we trust the public charging stations to have access to our data pins and being able to make data transfers? Probably not and that’s the gist of the recent warning.” There are ways to avoid the risk. “The best advice is to bring your own cables and adaptors. Then we can plug directly into power outlets,” Weldon said. If you must use a public charging station, he suggests using a data blocking USB cable. These cables only allow power to flow through, preventing any data transfer between the charging station and your device. Also, be aware if you are using your phone while charging it. “When using public charging stations we should, at a minimum, watch for strange behaviors, weird popups, and being asked questions about trusting the device or drive we’re connected to. Those are danger signs, and we’d want to disconnect quickly,” added Weldon. Another option to protect your phone from juice jacking is to use a wireless charger. These chargers do not require a physical connection between your device and the charging station. While wireless charging is typically slower than using a cable, it is a safe alternative when you’re on the go and need to charge your device. Keeping your personal information safe is crucial in today’s digital age. Protecting your phone from juice jacking is just one way to prevent hackers from accessing your sensitive data. Looking to know more? Connect with our expert today. Steven Weldon is the Director of Cyber Institute at the School of Computer and Cyber Sciences at Augusta University and is an expert in the areas of cellular and mobile technology, ethics in computer science, scripting and scripting and automation. Steve is available to speak with media - simply click on his icon now to arrange an interview today.

Podcast: Research into household chores reveals fascinating home truths
The notion of ‘women’s work’ still deeply embedded in today’s society Men’s choice of housework centred around machinery and perceived physical strength Some household tasks have ‘shifted’ over the years A fascinating study by an academic at Aston University has revealed that women still do certain traditional tasks within the home. The research by Dr Emily Christopher, a lecturer in sociology and policy, found that ‘woman-type’ tasks often involve multi-tasking while men’s roles often include solo duties such as mowing the lawn. Dr Christopher, whose research focuses on the reproduction of gender inequalities in paid and unpaid work, spoke about her study in the latest episode of the 'Society matters' podcast series, presented by journalist Steve Dyson. The episode is sub-titled 'Did you iron my shirt? Why household work, and who does it, matters'. Dr Christopher explained that men are doing much more household work than they did 50 years ago, and that there was “general agreement” among the couples she interviewed that household work should be shared. The lecturer, who invited couples to assign ‘task cards’ during interviews in their homes, said past research found that women still perform the ‘lion’s share’ of household work. This, she said, followed on from the “age old idea” of women being more caring and nurturing which was “deeply embedded in the way society thinks”. While some tasks were still more likely to be done by women, some had shifted over time. Tasks still “overwhelmingly gendered” today include women remembering birthdays, organising presents, and remembering whether a child needs PE kit or money for a cake sale, all the cognitive labour of household management. She said: “The problem is it’s invisible, so it isn’t recognised as work.” Dr Christopher said that men tend to do the ironing if they find it “enjoyable”, often while listening to football or music, or if they have “particular standards”, such as creases in their sleeves. However, some women choose ironing as a “form of protest”, doing their own and their children’s clothes but refusing to iron men’s shirts. Dr Christopher pointed out that some other tasks traditionally seen as women’s, which had ‘shifted’, included cooking. She said: “Men are more likely to do this now, arguably this might be because they are less likely to be seen as less masculine for doing so, this helped by the rise of celebrity chefs like Gordon Ramsay, Rick Stein and Jamie Oliver.” Her research also revealed that men are more likely to wash up and stack the dishwasher but, like ironing, men doing these tasks was often driven by standards such as liking them stacked a particular way. They are also more likely to hoover than to clean, which fell mostly to women, with Dr Christopher suggesting: “I wonder whether sometimes this is something to do with the fact that hoovering involves technology and machinery, so it conceptualises more as a masculine form of housework.” Similarly, Dr Christopher said men are more likely to do outside jobs such as DIY, washing the car and mowing the lawn, with the emphasis again on physical strength. Significantly, tasks which men are more likely to be responsible for, such as DIY, are less likely to “interfere” with paid work, whereas those done by women often involve a reduction in their hours with “very wide implications” such as a gender pay gap, restrictions in career progression, and restricted access to pensions in later life. As a result, she said the state needs to do more, particularly around parental leave and the lack of affordable childcare provision. Dr Christopher said: “If you take maternity leave, it’s 12 months maximum in comparison to one or two weeks’ paternity leave, so straight away we are sending a message about who’s the natural carer. Parental leave needs to change to challenge this reinforcing of gender roles.” She added that childcare provision needs to be seen as integral to the way society and the economy works, so needs funding. Increasingly, Dr Christopher said couples are relying on their parents for help with childcare, and “interestingly, it tends to be the grandmothers who take on this work”. Individuals wanting to put a monetary value on household work can complete the Office for National Statistics’ domestic labour calculator, although she said it was a crude measure and only gives a rough idea. “Using this measure, my household work, on top of a full-time job at Aston University, is worth £18,000 a year,” she said. Listen to all episodes of the 'Society matters' podcast

Members of the Lived Experience Stakeholder Group meet at Aston University for the first time to give feedback on the project MEDIATE investigated how medication for severe mental illness can be optimised Research funded by the National Institute for Health Research (NIHR). Researchers from Aston Pharmacy School welcomed people with lived experience involved in the MEDIATE research project to campus for a one-day workshop on 17 March to enable these members of the Lived Experience Stakeholder Group - who all live with and take medication for severe mental illness (SMI) - to meet in person to give feedback and discuss their participation in the project. The group members have participated in the National Institute for Health Research (NIHR) funded project since January 2022 until its conclusion in March 2023. The MEDIATE project investigated how medication can be best optimised (safely getting the right drug at the right dose to the individual at the right time) for people living with SMI. The first part of the workshop allowed participants to discuss with the research team their involvement as people with lived experience of severe mental illness in the project. Dr Jo Howe, MEDIATE project researcher at Aston University, said: “Although this group was formed to help us as researchers, we became aware that involvement in the group has also helped group members. They enjoyed linking with their peers, despite having had different lives and journeys, they discovered shared experiences, which helped them feel less isolated. “Importantly some members said that their involvement in our research improved their self-confidence and helped them to speak about their medication concerns with their healthcare team.” The second part of the workshop bought the group together to gauge opinions on three separate research projects currently being planned by the MEDIATE research team. The group were able to give useful insights to help shape the research teams future project proposals. Max Carlish, MEDIATE group member, said: “Our participation throughout this project has really made us feel that we have been influencing the direction of the research. With our unique service user perspectives helping to make the research findings practicable and applicable to the vitally important - and often overlooked - area of medication optimisation.” Mustak Mirza, MEDIATE group member, added: “People will trust their leaders when the leaders do the thing that make them feel psychologically safe. And I believe and feel you (the MEDIATE Team) have done that. Many thanks for being so kind.” Dr Jo Howe added: “Input from the group has been invaluable for this project. Their involvement has shaped the trajectory of our research and they have been instrumental in identifying gaps in the research evidence. “It really was fantastic to meet everyone in person, I felt like we connected at a deeper level and I’m really looking forward to working with everyone again on future research.” Professor Ian Maidment, MEDIATE project lead at Aston University, said: “It is vital that the people who this research affects are actively involved in the process. We aimed to do this in MEDIATE and working with this group has really helped inform the research. For example, any guidance or outputs we produce will be centred on real world experience and are therefore much more likely to have an impact.”

Candida auris: The deadly fungus is spreading and proving difficult to fight
Candida auris is making headlines - and for all the wrong reasons. The fungus can lead to severe infections causing long term health issues and even death. Recently, Fox News in Los Angeles was covering this emerging threat and reached out to Augusta University's Dr. Jose Vazquez for his expert insight and opinion. Here's the piece: The Centers for Disease Control & Prevention says Candida auris, or C. auris, is an emerging health threat, a type of fungus can cause severe, potentially life-threatening infections in people hospitalized with compromised immune systems. Dr. Jose Vasquez, chief of infectious diseases at the Medical College of Georgia at Augusta University, says there are several reasons for concern about this fungus. "The biggest fear is that it is multi-drug resistant," he says. "So, it is resistant to many different drugs." The CDC says most C. auris infections respond to antifungal medication, but some do not. Vasquez says C. auris is also hard to detect without highly specialized lab equipment that many hospitals do not have. And, he says, it is hard to stop the fungus once it gets into a hospital setting, such as an ICU or nursing care facility. C. auris can live on a person's skin without causing symptoms, allowing it to be transmitted from one person to another, or to get into a patient's body through contaminated surfaces or medical equipment like mechanical ventilators, feeding tubes and central lines. 'It is one of the Candidas that lives the longest on a surface, and we're talking about weeks," he sys. "So it can live there, dry and desiccated. Once it gets there, it kind of sets up shop, and it is very, very difficult to eradicate." The rest of the news story is attached: Looking to know more? That’s where Augusta University can help. Dr. Jose Vazquez, division chief and professor of Medicine at the Medical College of Georgia, is an expert in the realm of infectious diseases. He studies and treats infectious diseases, including antibiotic-resistant superbugs and fungal infections. He has been a reliable source for local, statewide and national media regarding the coronavirus outbreak. Dr. Vazquez is available to speak with media regarding this topic – simply click on his icon to arrange an interview.

• Has potential to help geneticists investigate vital issues such as antibacterial resistance • Will untangle the genetic components shared due to common ancestry from the ones shared due to evolution • The work is result of a four-year international collaboration. Aston University has worked with international partners to develop a software package to help scientists answer key questions about genetic factors associated with shared characteristics among different species. Called CALANGO (comparative analysis with annotation-based genomic components), it has the potential to help geneticists investigate vital issues such as antibacterial resistance and improvement of agricultural crops. This work CALANGO: a phylogeny-aware comparative genomics tool for discovering quantitative genotype-phenotype associations across species has been published in the journal Patterns. It is the result of a four year collaboration between Aston University, the Federal University of Minas Gerais in Brazil and other partners in Brazil, Norway and the US. Similarities between species may arise either from shared ancestry (homology) or from shared evolutionary pressures (convergent evolution). For example, ravens, pigeons and bats can all fly, but the first two are birds whereas bats are mammals. This means that the biology of flight in ravens and pigeons is likely to share genetic aspects due to their common ancestry. Both species are able to fly nowadays because their last common ancestor – an ancestor bird - was also a flying organism. In contrast, bats have the ability to fly via potentially different genes than the ones in birds, since the last common ancestor of birds and mammals was not a flying animal. Untangling the genetic components shared due to common ancestry from the ones shared due to common evolutionary pressures requires sophisticated statistical models that take common ancestry into account. So far, this has been an obstacle for scientists who want to understand the emergence of complex traits across different species, mainly due to the lack of proper frameworks to investigate these associations. The new software has been designed to effectively incorporate vast amounts of genomic, evolutionary and functional annotation data to explore the genetic mechanisms which underly similar characteristics between different species sharing common ancestors. Although the statistical models used in the tool are not new, it is the first time they have been combined to extract novel biological insights from genomic data. The technique has the potential to be applied to many different areas of research, allowing scientists to analyse massive amounts of open-source genetic data belonging to thousands of organisms in more depth. Dr Felipe Campelo from the Department of Computer Science in the College of Engineering and Physical Sciences at Aston University, said: “There are many exciting examples of how this tool can be applied to solve major problems facing us today. These include exploring the co-evolution of bacteria and bacteriophages and unveiling factors associated with plant size, with direct implications for both agriculture and ecology.” “Further potential applications include supporting the investigation of bacterial resistance to antibiotics, and of the yield of plant and animal species of economic importance.” The corresponding author of the study, Dr Francisco Pereira Lobo from the Department of Genetics, Ecology and Evolution at the Federal University of Minas Gerais in Brazil, said: “Most genetic and phenotypic variations occur between different species, rather than within them. Our newly developed tool allows the generation of testable hypotheses about genotype-phenotype associations across multiple species that enable the prioritisation of targets for later experimental characterization.” For more details about studying computer since at Aston University visit https://www.aston.ac.uk/eps/informatics-and-digital-engineering/computer-science





