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Researchers awarded £2 million to develop drugs to prevent epileptic seizures in children
• Three-year research project to develop new drug treatments for childhood epilepsy • Scientists will test new treatment on pieces of living brain tissue • The research is a collaboration between Aston University, Bristol University and Jazz Pharmaceuticals. Scientists at Aston University have started work on a project that will look for new drug treatments to prevent the onset of childhood epilepsy. The three-year Medical Research Council (MRC) funded project is a collaboration led by researchers in the College of Health and Life Sciences at Aston University, partnered with Bristol University and Jazz Pharmaceuticals. They have been awarded £2 million to explore how epilepsy becomes established in the brain and how this process might be prevented. The researchers will test new drugs in the human brain, using samples of living tissue taken from children with difficult to treat epilepsies who have had to have brain surgery. Epilepsy is a brain disease which is characterised by seizures. As Professor Gavin Woodhall, lead researcher and co-director of Aston Institute of Health and Neurodevelopment, explains: “Seizures are periods of time when networks of brain cells are too active and are uncontrollably excited and spiking. If uncontrolled excitation spreads to brain regions that control movement, then too many brain cells are ‘talking at the same time’ and we can see seizures as changes in movement such as jerks and twitches.” Upon receiving the grant, Professor Woodhall said: “We will be able to study epilepsy in such detail that we hope to be able to treat the problems that underly epilepsy and not just the seizures themselves. And this could help pave the way to prevent epilepsy from developing in children at all. “Essentially we want to find a treatment that stops the brain from being able to establish epilepsy after the first seizure - via a new drug treatment. We will be testing a known drug and a new drug to see if the drug can do this.” As part of the research for this project the scientists will look at how different amounts of epileptic activity in the brain can alter the brain’s excitability. The researchers predict that if there are a lot of seizures, the synapses in the brain will decrease their activity and brain cells will become more likely to spike. Professor Woodhall added: “This is why we will test antiepileptic drugs, and new drugs designed to interfere with homeostatic scaling - which is a form of plasticity, in which the brain responds to chronically elevated activity in a neural circuit with negative feedback, allowing individual neurons to reduce their overall action potential firing rate. “By interfering with homeostatic scaling we will be able to see if they can prevent seizures from developing or reducing their intensity.” The research will allow Professor Woodhall and his team to be able to record the life history of the disease. This is something which has not been done before in this level of detail and it is predicted it will help to shed light on how epilepsy initially develops in the brain. Following on from the three-year project the team will move into drug development and then clinical trial. For more information about research being undertaken at AIHN please go to our website. If you are interested in the courses we have available in this area please go to our course pages.
New research highlights the economic importance of live music to Birmingham and the West Midlands
It found local authorities need to more explicitly recognise the economic, social and cultural value of live music and live music venues The report calls for dialogue between music stakeholders and government The research is published by Aston University and supported by the AHRC-funded Creative Industries Policy and Evidence Centre. New research by the Birmingham Live Music Project (BLMP) highlights the huge economic value of Birmingham’s live music scene, the vital contribution small independent venues make, the ongoing impact of the pandemic and what is needed to support the recovery of the sector in the city. The research is published by Aston University, with colleagues from Newcastle University and Birmingham City University, and supported by the Arts and Humanities Research Council (AHRC)-funded Creative Industries Policy and Evidence Centre. In 2019, the UK’s live music sector was valued at over £1.3 billion. After almost a decade of strong growth the sector helped push the UK music’s overall GVA from £3.5 billion in 2012 to £5.8 billion in 2019, the outbreak of the global pandemic brought it to a near standstill. This paper explores, through a local lens and a focus on Birmingham, the challenges stakeholders across the live music sector have faced in recent years. The research finds that small live music venues are the lifeblood of this financial, cultural and community asset for the city. In 2019 Birmingham helped bring 877,000 music tourists to the West Midlands, with a total cultural spend in the region of £252,000,000 (UK Music). But during summer 2020, the research published today found, Birmingham’s live music capacity of approx. 98,000 dropped by around 75%. This impacted ticket prices, the availability of events across the city, and the economic viability of shows – while some venues could stay open, they couldn’t make a profit. The report makes clear independent venues need protection and support particularly in the wake of the pandemic. It calls for dialogue between music stakeholders and government in advance of the 2025 review of the EU-UK Trade and Co-Operation Agreement to identify the best means of reducing friction and support for the efforts to improve the Agreement, for example work on border force training, expanding the number of checkpoints where carnets and Music Instrument Certificates can be checked, reducing bureaucracy for live event transport and haulage, examination of further measures to develop the ’dual registration’ system for specialist hauliers to ease pressure on touring. Dr Patrycja Rozbicka, a senior lecturer in politics and international relations at Aston University and one of the report authors, said: “Local authorities need to more explicitly recognise the economic, social and cultural value of live music and live music venues, including grassroots venues, to their region(s). “Environmental, health, culture and city regeneration strategies have to take account of the existing and huge potential contribution of live music to the city and region. “What is needed is a cross-policy approach, implementation of a Night-time Industry Impact Assessment and dialogue between local authorities and the music sector, where the recently launched West Midlands Music Board could play a role. “We would like to see the creation of information hubs to support local venues and audiences with initiatives such those undertaken by the Liverpool City Region including a Music Fund which supports activities of the Liverpool City Region Music Board as well as helping with funding applications and advice. You can read the full report here.
Gene Editing Institute Travels to Salem for ‘Innovation Days’ Workshop
Education sessions bring CRISPR gene editing to high school students from diverse backgrounds Scientist-educators from ChristianaCare’s Gene Editing Institute held a workshop using CRISPR in a BoxTM at Salem Academy during Innovation Days in October at the school, located in Winston-Salem, North Carolina. These sessions followed a previous gene editing education workshop with Salem Academy students in January 2022. CRISPR in a BoxTM is a revolutionary toolkit that allows students to carry out a hands-on gene editing experiment while learning and analyzing the steps involved in a typical gene editing reaction. Scientists from the Gene Editing Institute also taught a condensed lesson about CRISPR gene editing’s utility in medicine and fielded questions from students about jobs in biotechnology, bioethics and sustainability in the lab. “It’s a really special opportunity that I know I wouldn’t get anywhere else,” said Mathilda Willenborg, a sophomore boarding student from Germany. “And I do feel like I’m learning a lot about gene editing that I definitely didn’t know before. The team makes it really easy and walks us through all the steps.” Last winter, Salem Academy became the first school in North Carolina to offer CRISPR in a Box as it pivoted its academic focus to STEAM (Science, Technology, Engineering, Art and Math). That first innovative workshop originated as a result of an idea from a ChristianaCare board member who attended Salem Academy. Gene Editing Institute Founder and Lead Scientist Eric Kmiec, Ph.D., made a virtual appearance as part of the latest sessions to encourage the students to pursue careers and pathways in biotechnology. “We’re so appreciative of our partnership with Salem Academy,” said Kmiec. “We want to take every chance we get to encourage more women to pursue careers in STEM. Women around the nation, and around the world, should have access to this groundbreaking technology, which will ultimately drastically change the way we treat and cure diseases. If we don’t have young women in that discussion, we’re missing out on valuable experiences and perspectives.” Salem Academy is the only all-female boarding and day high school on a college campus in the U.S. with a STEM focus. Women are achieving significant progress in STEM fields, representing 45% of students majoring in STEM, according to the Integrated Postsecondary Education Data System. However, women only represent 27% of STEM workers, with wide disparities in income in post-graduation employment. As of 2019, less than 30% of the world’s researchers were women, according to the UNESCO Institute for Statistics. The Gene Editing Institute commits to a mission of diversity and equity in its approach. This workshop reached 10 women, two of whom are international students. “Our ongoing partnership with the ChristianaCare Gene Editing Institute will help position our aspiring women scientists for future careers in biotechnology, science and medicine,” said Summer McGee, Ph.D., president of Salem Academy and College. “This is the type of experience that sets Salem Academy apart as a national leader in building the next generation of women leaders in STEAM.” The Gene Editing Institute itself is a national leader in female researchers. Women make up over 80% of scientists within the Institute and fill 75% of the principal investigator roles. The Institute pushes to address the gender gap and promote inclusivity through local outreach and state-spanning programs, like CRISPR in a Box. “We’re not here to do lip service,” said Brett Sansbury, Ph.D., principal investigator of the Discovery Branch of the Gene Editing Institute. “Too many companies make a plan or promise without any actionable steps. We’re taking those steps and bringing in opportunities for students who otherwise wouldn’t have had them.” To learn more about how to bring CRISPR in a Box to your school, visit https://geneeditinginstitute.com/products/education. About CRISPR in a BoxTM CRISPR in a BoxTM is the leading educational toolkit to teach gene editing. The exercise features a hands-on gene editing experiment, including a live readout within non-infectious E. coli bacteria. These experiments follow a gene editing reaction from beginning to end while teaching students the techniques scientists use to perform these reactions in real laboratory environments. CRISPR in a Box is distributed by Carolina Biological. To learn more, visit https://geneeditinginstitute.com/products/education.
• University expert helps clothes designer measure and tackle their carbon emissions • Upcycler, ‘Missfit Creations’, has saved CO2 equivalent of three tonnes • Call to COP27 to issue a protocol to measure all garments’ environmental impact. 8 November 2022 | Birmingham UK As policymakers at COP27 are to discuss the effects of the fashion industry on the environment, an Aston University scientist has been helping a clothes designer measure and tackle their carbon emissions. Debbie Murphy runs Missfit Creations which provides an alternative to fast fashion. She saves clothes from clogging up landfill by restoring and reworking second-hand and vintage clothing, from de-mob suits and 1970s psychedelia, to the present day. Dr Maria Pimenta da Costa Ocampo, a researcher from the Energy & Bioproducts Research Institute (EBRI) at Aston University, has been identifying the impact the business is having on reducing carbon emissions. By analysing the recirculation of second-hand clothes alone, she found Debbie’s current fashion collection has the potential to save the CO2 equivalent of three tonnes – equal in size to at least three semi-detached houses. The support provided to Tamworth-based Missfit Creations was through EBRI's European Regional Development Fund (ERDF) programme that helps West Midlands companies develop low carbon goods and services. Debbie said: “It was eye-opening to work with Aston University. “I collect and restore a huge amount of old, unwanted clothes that would otherwise have ended up in landfill, so I decided to find out what impact my business has on the environment. “I knew my business would help tackle the effects of fast fashion, but I didn’t realise I’ve been able to prevent the production of so much CO2. “Raising awareness of second-hand clothes over fast fashion, and the increased awareness of clothing care efficiency will help reduce the carbon footprint of the textile industry.” The Aston University report also suggests ways the business can further decrease emissions. As a result, it will be introducing a ‘take-back’ scheme, offering vouchers or exchanges in return for previous purchases. Debbie will also be changing production methods by ensuring all packaging is biodegradable, ironing fabrics less and switching to a more sustainable energy provider. The COP27 fashion charter event (11 November 2022) will explore whether the sector’s planned transformation to net zero is underway, practical solutions that are being applied and what is needed to achieve the goal. However, Dr Pimenta-Ocampo said: “Every single action taken towards the production and recirculation of clothing has an environmental impact. “For example, we calculated that by recirculating vintage clothing, Missfit Creations was reducing CO2 equivalent by almost two tonnes just by diverting clothes from landfill. “And by outsourcing their vintage clothes for cleaning services that don’t use tumble driers, not taking into account transport emissions, Missfit Creations is reducing CO2 equivalent by another one tonne. “There is a great need for the textile industry to monitor and provide accurate data and to become more transparent, specially when global supply chains are involved. “However, the creation of a protocol and standardisation of the Life Cycle Assessment, which measures a product’s environmental impact from raw material to final disposal, is also required. Without it, it will be impossible to produce results that can be representative.”
Aston University and Birmingham Women’s and Children’s NHS Foundation Trust (BWCH) have pledged to work together to address health provision in the city by signing a Memorandum of Understanding to co-develop paediatric health initiatives and the health services workforce of the future to deliver them. The strategic partnership between the University and BWCH aims to develop the health services workforce of the future together (particularly focusing on course development and delivery, including placements). It will also invest in shared posts that support closer links between academic, education and healthcare provision and support honorary appointments and initiate collaborative projects including joint research, to develop world-leading research and provision in the field of paediatric health and wellbeing. The partnership will make the most efficient use of resources and reduce duplication by providing a range of shared services, as well as continuously developing new ways to work together, with a view to supporting innovation in the field of healthcare. These activities will build on the existing joined up work taking place between Aston University and Birmingham Women’s and Children’s NHS Foundation Trust, such as shared use of the MRI scanning services in the Aston Institute for Health and Neurodevelopment and joint research projects examining topics including epilepsy in children, eating behaviours and neurodevelopment. Both organisations are also members of Birmingham Health Partners, the city’s clinical-academic research alliance, which includes maternal health as one as its key strategic focus areas. Professor Anthony Hilton, pro-vice-chancellor and executive dean of the College of Health and Life Sciences at Aston University, said: “The signing of this Memorandum of Understanding formalises the existing relationship between our two organisations and represents a strong joint commitment to improving healthcare provision in our city. “Working collaboratively enables us to bring together world-leading research with outstanding clinical provision, for the benefit of our students, patients accessing BWCH services and our city and region. I look forward to developing the many ways in which our organisations can work together to improve healthcare provision in Birmingham.” Matthew Boazman, deputy chief executive officer of Birmingham Women’s and Children’s Hospital NHS Foundation Trust, said: “The partnership between BWCH and Aston University represents a wonderful opportunity for us to ensure that Birmingham has access to world-class healthcare provision and that those entering the workforce are as ready as they can be.”
Everyone is keeping a close eye on the economy. Whether on a global scale or at the kitchen table - it's a topic that is at the top of everybody's mind these day. Simon Medcalfe, PhD is the Cree Walker Chair in the Hull College of Business at Augusta University and resident expert on the economy, and he shared his thoughts on where the economy stands as the final months of the year approach. Q: The Gross Domestic Product report was up, what should we take out of that? “The GDP was interesting because it was actually up. The first two quarters were negative growth, so the economy had shrank. This time, the growth figure came in at 2.6%, but closer reading suggested it was actually a worse reading then the negative readings we had because consumer spending by firms was essentially flat. The growth was seen in net exports or government spending or things like. Consumers were kind of pulling back a little, which is why earnings were a little lower as well.” Q: The economy needs to slow down a little, doesn’t it? “I mean, yes, if you’re thinking about the Fed, that’s what they are worried about right now, inflation, because the economy is so incredibly hot, particularly with regards to prices. They’re raising interest rates with the aim at slowing down the economy. Unemployment is historically very, very low, if not at record levels in different places, so we could probably sustain a little slowing of the economy without impacting the labor market too much and try to get this general inflation under control.” Q: The economy could use a little unemployment, it’s that kind of counter intuitive? “Some unemployment is not bad. Economist use to suggest in the long run, the natural rate of unemployment is about 5-6%. Now we have unemployment in the 2-3% range in places. We have a little bit of wiggle room to see that increase.” Q: What's the difference between frictional and structural unemployment? "Economist talk about frictional unemployment and structural unemployment. Frictional unemployment is more of a job match or job search problem. So it’s a lack of information. Structural unemployment is because of the changing nature of industry within an economy. An example being people working in textile manufacturing and it’s hard for them to go straight into computer science coding because they don’t have the skills. This is more long term than frictional and in some cases can be quite detrimental to regions and people.” Q: The Fed is likely to raise interest rate by .75%, are there signs of this slowing down? “I think they’ll start slowing that down over time, but I think their projection is about 4.6% and we’re like 3.25% now. They’re looking at all the economic indicators. Not looking at any one or two, but everything. They’re looking at inflation, and have different measure of that. They’re look at the breakdown of inflation like how much of it is due to the war in Ukraine, and what areas of the economy it may be impacting. They’re looking at the labor market, definitely looking at manufacturing output, etc. The one thing they don’t generally look at is financial markets. They would look at the housing market though and different sectors of the real economy, not the financial economy.” Dr. Simon Medcalfe is a highly regarded economics expert in the Hull College of Business at Augusta University. Medcalfe is available to speak with media regarding the economy and its outlook – simply click on his icon now to arrange an interview today.
New approach to help ease poor countries’ debt burden Many face having national credit rating downgraded Aston University expert coins the term the ‘credit rating impasse’ in new book. An Aston University financial regulation expert has suggested a new approach to help ease poor countries’ debt burden. Currently many poorer countries face having their credit rating downgraded if they ask private investors for loans. Dr Daniel Cash, senior lecturer in law and founder of the Credit Rating Research Initiative, has suggested that a temporary change to the way ratings are decided could help these countries avoid a damaging credit rating, which would prevent them borrowing money in the future. His theory is explored in his new book Sovereign Debt Sustainability: Multilateral Debt Treatment and the Credit Rating Impasse. The study details the history of multilateral debt treatment in Africa, whilst also looking at the impact of the pandemic. When vulnerable countries try to negotiate new lending terms with their lenders their credit rating is immediately downgraded, in some cases they could be labelled as in default - failing to repay a loan. Dr Cash calls this situation the ‘credit rating impasse’. To avoid this happening, he argues that other factors should be temporarily taken into account, making it easier for them to borrow money in the future to spend on improvements such as healthcare or infrastructure. The UN has identified 54 developing economies with severe debt problems. While accounting for little more than 3% of the global economy, they represent 18% of the world’s population, and more than 50% of people living in extreme poverty. The book sets out a new framework which could be used to overlie the existing credit rating system. The book suggests considering factors such as ESG (Environmental, Social and Governance) – which indicates a country’s impact on society, the environment, and how transparent and accountable it is. Taking ESG and sustainability factors into account indicates if a nation has the potential to grow while benefiting the environment and communities. Dr Cash said: “The credit rating impasse is a systemic problem, and a cure is needed to prevent the bankruptcy of countries around the world. “Lower-income states are being forced to prioritise debt payments over public spending on healthcare or access to food. “Instead, they should be offered help to enable borrowing to make vital improvements.” The book is free to read via Open Access Book and was funded by the Open Society Foundations (OSF).
MEDIA RELEASE: CAA Insurance launches Auto Extension Insurance in Manitoba
New market expansions mean more Canadians have flexibility and choice from a trusted brand for their auto extension insurance needs. CAA Insurance is proud to announce the expansion of its Auto Extension Insurance into Manitoba and is now the underwriter for the same coverage in Saskatchewan. A top-up to the basic mandatory coverage available in the market, CAA Auto Extension Insurance allows policyholders more flexibility and choice to protect their vehicles and their family members “Life is unpredictable, and sometimes, basic coverage just isn’t enough,” says Matthew Turack, President, CAA Insurance. “That’s why we set out to develop a product that meets individual needs and the changing lifestyles of people who live on the prairies.” In Manitoba, CAA Insurance has entered the auto extension insurance market in the prairie province for the first time. The CAA Auto Extension Insurance product includes five new to-market coverages such as; Claim Forgiveness, Tire Pothole and Puncture Protection, Family Pet Protection, Emergency Expenses, and Personal Property coverage. Other available coverage includes auto loss of use, replacement cost coverage, extra liability coverage, reduced deductibles, and more. It is also the first time CAA Insurance is underwriting Auto Extension Insurance in Saskatchewan. CAA’s Auto Extension Insurance does not replace the mandatory coverage found through provincial government insurers but instead is a way for people to enhance their policy and give them more peace of mind. Policyholders may also be eligible for special discounts to save money including a CAA Member Discount, Winter Tire Discount, Multi-Vehicle Discount, and Multi-Line Discount. “As one of Canada’s most trusted brands, customers can enjoy peace of mind knowing they have the extra protection they need at the best possible price from a company they can trust,” says Turack.
West Grove Campus Awarded $2.5M Grant from Chester County for Capital Improvement Projects
Funds earmarked for information technology, medical equipment and facility upgrades The ChristianaCare West Grove campus has received a $2.5 million American Rescue Fund Plan Act (ARPA) grant from the Chester County Government for capital improvement projects related to information technology, medical equipment and facility renovation. ChristianaCare finalized the purchase of its West Grove campus (formerly Jennersville Hospital) from Tower Health in June 2022. The hospital has been closed since Dec. 31, 2021. “We are enormously grateful to the Chester County Commissioners for this generous grant,” said Douglas Azar, MHA, ChristianaCare senior vice president, Strategic Clinical Integration. “Our assessment and inventory of the facility indicate that while it contains some usable equipment, including hospital beds and some imaging and diagnostic equipment, there is a lot of work to be done in many key areas. For example, the building currently contains no information technology infrastructure and no laboratory equipment. This funding will provide much-needed help as we build out these critical areas,” he said. “This grant is a tremendous resource as we plan next steps for the West Grove campus,” said Heather Farley, M.D., MHCDS, FACEP, ChristianaCare’s co-lead for the campus development strategy. “Ensuring that the facility has the very best technology and medical equipment will enable us to provide expert care to our neighbors in southern Chester County for many years to come.” The Chester County Commissioners approved ARPA grants to 73 groups and organizations totaling close to $40 million last month, following recommendations by six independent review teams. The teams, comprised of county residents and county government staff, developed a system that followed ARPA guidelines to review proposals and address priorities for funding. “These funds represent a substantial investment in much-needed local programs and services including support for public health,” said County Commissioners’ Chair Marian Moskowitz. “Being able to financially assist ChristianaCare as they work toward bringing hospital services back to southern Chester County firmly met ARPA guidelines and was very important to us.” (From left) Bettina Tweardy Riveros, Chief Health Equity Officer and Senior Vice President, Government Affairs and Community Engagement at ChristianaCare, Marian Moskowitz, Chair of the Board of Commissioners of Chester County, Michelle Kichline, Chester County Commissioner, Heather Farley, M.D., MHCDS, FACEP, ChristianaCare’s co-lead for the campus development strategy and Douglas Azar, MHA, ChristianaCare senior vice president, Strategic Clinical Integration Commissioner Josh Maxwell added that “when ChristianaCare stepped up to take over Jennersville Hospital and bring health care services back to the county, we pledged to support them in those efforts in ways that we, as county government, can. The ARPA program has provided us with the opportunity to fulfill that pledge, with funding that might otherwise be cost-prohibitive.” ChristianaCare is reimagining health care at the West Grove campus and is taking a phased approach to the opening of services. The first phase will be to re-establish emergency services. Subsequent phases are still under consideration. Due to required facility upgrades and plan development, it is unlikely that any services will open within the next 12 months. Since June, Azar, Farley and others at ChristianaCare have participated in meetings and listening sessions with community leaders and small groups to gain input into planning for services at the campus. They have met with local and state government officials, school officials, chambers of commerce, nonprofit organizations, emergency responders, faith leaders and employers in the area. Commissioner Michelle Kichline noted the correlation between ChristianaCare’s focus on meeting community needs and the county’s focus on community involvement in the ARPA grant review process. “Having county residents involved in reviewing and recommending our ARPA applications has been exciting and rewarding,” she said. “They know their local communities best and evaluated and selected projects that address needs across the county. “We know that ChristianaCare is doing the same and see the $2.5 million ARPA grant as a smart investment in restoring crucial health care services to our residents.” The West Grove campus represents a significant expansion and commitment of ChristianaCare to provide health services to communities in southern Chester County. Since 2020, ChristianaCare has added three primary care practices located in Jennersville, West Grove and Kennett Square. Combined, these three practices are now the “medical home” for 22,000 residents in these communities.
Are butter boards bad for you? An expert view on the latest food trend
In an unexpected twist, butter seems to be back on the menu. After years of being a maligned ingredient that many people shied away from, butter has now become the latest food trend on social media, thanks to the recent popularity of “butter boards”. These are sort of the meat-free equivalent of a charcuterie board. Butter is whipped then spread onto a chopping board, sprinkled with a variety of toppings – from sweet to savoury – and served with an accompaniment of choice (such as bread or a toasted baguette). But although they may be delicious, butter is still full of saturated fat – which many of us know can be harmful to our health. Here’s what you may want to consider before whipping up a butter board of your own. Is butter really that bad? Butter is made from cream, the fat-rich part of milk. While it’s usually made from cow’s milk, it can also be made from other milks such as goat milk. The reason that butter has been seen as a no-go for so many years is because it’s one of the ultimate sources of saturated fat. Butter contains around 80% fat, of which about two-thirds is saturated fat. It contains little else nutrient-wise. Saturated fats should be avoided in large amounts as they’re linked with many health problems, including heart disease and shorter life expectancy. Clinical trials have also shown that saturated fats can have an negative effects on blood cholesterol levels. When it comes to butter on its own, it appears that eating it has a relatively small or neutral effect on the risk of heart disease. But research that compared butter to olive oil (another source of saturated fat) found that butter can increase levels of LDL cholesterol, which is sometimes called “bad” cholesterol as it’s linked to greater risk of heart disease. But the majority of the butter many of us consume in our diets comes from other foods such as biscuits, cakes and pastries. Alongside butter, these foods tend also to contain high amounts of sugar, while being low in other nutrients. High intakes of these types of foods is also linked with greater risk of heart disease. Overall, sharing a butter board with friends every now and then is unlikely to cause much harm to your health. But doing it often, or eating very large quantities, could raise cholesterol levels and increase your risk of cardiovascular disease somewhat. It’s also worth bearing in mind what toppings you serve your butter board with. Certain foods (such as processed or cured meats) also contain saturated fats, and should only be enjoyed occasionally. Butter alternatives Since butter is very calorific and fat-rich, some people may want to look at using butter alternatives for the base of their butter board. The first substitute many people might look to is margarine. Margarine is chemically very similar to butter. Depending on the product though, it only contains around 40%-70% fat, making it a lighter alternative with a possibly similar taste. In the past, the processes needed to make margarine solid resulted in the production of trans fats, which have been linked to increased risk of heart disease. But these processes have since been improved so margarine no longer contain trans fat. So it may be a good option for people wary of the amount of fat they consume. Another alternative people may look at using is ghee, also sometimes known as clarified butter. A staple of Indian cooking, this is still made from milk, but the fat is much more concentrated as most of the water has been simmered away. This means it won’t have the same creamy texture as butter. Grass-fed ghee is as rich in saturated fats as butter. It also contains naturally produced trans fats. However, these trans fats are different to the industrially produced types which are bad for our health. But since ghee contains more calories than butter, it may not be the best choice for a butter board, especially if you’re looking for the best flavour. Cultured butter may also be a choice for your butter board. This is made from cream which has been fermented like yoghurt. However, no research to date has looked at whether the probiotics in cultured butter provide the same health benefits as those in yoghurt and other fermented foods. Nutrition-wise, it contains the same amount of fat and calories as regular butter. All in all, butter is not bad. But since it’s very high in calories and cholesterol, you may want to try not to have too much. Sharing a butter board with some friends or loved ones every now and again is unlikely to have any long-term negative impact on your health.
