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Toolkit is easily incorporated into any laboratory science course Wilmington, Del., April 1, 2021 – St. Georges Technical High School in southern New Castle County, Delaware is the first high school in the United States to use ChristianaCare Gene Editing Institute’s innovative CRISPR in a Box Educational Toolkit™ in a science class. CRISPR in a Box brings to life the much-heralded CRISPR gene editing technology – the “genetic scissors” that allow scientists to edit DNA. The toolkit is designed for educational sessions in secondary and post-secondary schools and is suitable for remote learning. “Gene editing is the future of medicine,” said Eric Kmiec, Ph.D., director of ChristianaCare’s Gene Editing Institute. “Our partnership with the Delaware Department of Education will help cultivate the next generation of genetic scientists and enhance Delaware’s position as a leader in the biosciences.” “We are thrilled that students at St. Georges Technical High School will be the first In the United States to experience a live demonstration of CRISPR gene editing using our Innovative CRISPR in a Box educational toolkit,” said Siobhan Hawthorne, Education and Community Outreach leader at ChristianaCare’s Gene Editing Institute. “This toolkit will provide STEM students with a visual understanding of how the exciting CRISPR technology can unlock medical treatments to improve lives.” Delaware Secretary of Education Susan Bunting praised her department's partnership with ChristianaCare's Gene Editing Institute to develop the “Seeds of STEM” course that teaches high school students about gene editing. “Gene editing approaches diseases in new ways and will have significant impact in the health care and agriscience fields,” Bunting said. “This is a great example of an industry and education partnership investing in youth by providing hands-on knowledge and skills around emerging technology.” “We are so fortunate that ChristianaCare’s Gene Editing Institute reached out to our program to plan a high school ‘first’ opportunity with this new CRISPR experiment,” said Danya Espadas, one of the St. Georges biotech teachers. “Giving students the chance to use a cutting-edge, 21st century tool for medicine in their own high school lab – to have that technology at their fingertips – transcends what they see in a textbook or a video. By being able to do it themselves, it makes it real for them.” Espada said the experiment focuses on editing a gene of a non-infectious E.coli bacteria to become resistant to an antibiotic, thereby allowing researchers to create a new class of antibiotics that cannot be overcome by bacteria that are gene resistant. “We’re talking about eventually saving lives, here,” she said. “What can be more important than that?” The tools in CRISPR in a Box have been designed based on the pioneering discoveries of the Gene Editing Institute that are currently being used to explore next-generation medical therapies and diagnostics for diseases, including lung cancer and sickle-cell anemia. Component items in the toolkit include the CRISPR/Cas complex, a target DNA molecule, a mammalian cell free extract and a synthetic DNA molecule. All materials in the kit are safe, synthetic materials. There are no live cultures or viruses involved. The kit is meant to provide a hands-on demonstration of CRISPR’s capabilities, and not allow for manipulations of living organisms. “The kit is easy and fun to use,” said Kristen Pisarcik, research assistant at the Gene Editing Institute who has taught students at Delaware Technical Community College which first used the toolkit. “In a short period of time students will reliably and successfully complete the laboratory activity and be able to see the results of gene editing,” she said. Since the foundations of the kit touch upon key themes in biology, it can be readily incorporated into practically any science or biology course with a laboratory component, “One of the beauties of CRISPR in a Box is that there is no need to purchase specialized equipment. If a teaching lab can support bacterial cultivation, it can perform the in vitro gene editing lab activity,” Pisarcik said. CRISPR in a Box is the evolution of a partnership between the Gene Editing Institute, Delaware Technical Community College and Rockland Immunochemicals that began in 2017 with a National Science Foundation grant to develop the first-ever gene editing curriculum for community college students. Video and photo collection of first class in U.S. to use CRISPR in a Box™ educational gene editing toolkit. About ChristianaCare’s Gene Editing Institute The Gene Editing Institute, a worldwide leader in CRISPR gene editing technology and the only institute of its kind based within a community health care system, takes a patient-first approach in all its research to improve the lives of people with life-threatening disease. Since 2015, researchers at the Gene Editing Institute have been involved in several ground-breaking firsts in the field, including the development of the first CRISPR gene editing tool to allow DNA repairs outside the human cell which will rapidly speed therapies to patients and a unique version of CRISPR called EXACT that reduces the number of off-target edits to other areas of the genome, which is vital for further research and patient applications. Its researchers are currently developing a patient trial for lung cancer using CRISPR and employing the technology to combat the COVID-19 pandemic. About the biotech program St. Georges Technical High School The Biotech career program of study at St. Georges Technical High School is the first such program offered in a Delaware high school. With two teachers and approximately 100 students in grades 10-12, the program presents advanced content in biology and chemistry with opportunities for students to learn basic laboratory techniques and procedures and to maintain and operate common instruments and equipment used in a biotechnology laboratory. St. Georges is a comprehensive career and technical high school with 1,100 students who study in one of 16 different career pathways.
How worried should you be about coronavirus variants? A virologist explains his concerns
Paulo Verardi, Associate Professor of Virology and Vaccinology at UConn, was asked to lend his expertise and opinion to The Conversation about coronavirus variants and just how concerned Americans should be about the emergence of variants and the speed at which they are spreading across the country and the globe. Spring has sprung, and there is a sense of relief in the air. After one year of lockdowns and social distancing, more than 171 million COVID-19 vaccine doses have been administered in the U.S. and about 19.4% of the population is fully vaccinated. But there is something else in the air: ominous SARS-CoV-2 variants. I am a virologist and vaccinologist, which means that I spend my days studying viruses and designing and testing vaccine strategies against viral diseases. In the case of SARS-CoV-2, this work has taken on greater urgency. We humans are in a race to become immune against this cagey virus, whose ability to mutate and adapt seems to be a step ahead of our capacity to gain herd immunity. Because of the variants that are emerging, it could be a race to the wire. April 08 - The Conversation Dr. Verardi discusses the the five SARS-CoV-2 variants we all need to be watching, the rates of transmission and the severity of symptoms, and why we all need to remain on guard and get vaccinated. It is a great article, and if you are a journalist looking to cover this topic, then let us help with your stories. Dr. Paulo Verardi is a virologist who specializes in vaccine research and development and is a member of the Center of Excellence for Vaccine Research. Dr. Verardi is available to speak with media regarding variants and COVID-19 – simply click on his icon now to arrange an interview today.
The Zoom Boom? More and more Americans are getting plastic surgery – let our expert explain why
After almost a year where most American offices went unused, experts are noticing an unexpected side effect from all those online meetings. It appears that prolonged exposure to seeing yourself in that tiny box during video calls is inspiring a sudden uptick in plastic surgery. The plastic surgery industry is booming during the coronavirus pandemic, largely due to the increase in the number of virtual meetings offered through Zoom and other video web services. Call it the “Zoom boom.” The interest in cosmetic surgery is boosting appointments for Botox, lip fillers and other plastic surgery procedures that help people feel more attractive on computer screens, according to Dr. Maria Helena Lima, an assistant professor of Surgery for the Section of Plastic and Reconstructive Surgery in the Medical College of Georgia at Augusta University. “In the last few months, there has been a jump in the number of patients wanting plastic surgery procedures,” said Lima. “We have discovered that when people are in Zoom meetings, they should be listening to the content and paying attention to what’s going on, but they’re not.” Lima says participants are oftentimes looking at themselves on the screen and wondering what could be done to alter their image. It is a trend that offers up some interesting questions: • Along with the Zoom boom, are there other reasons people are opting to go under the knife for an elective procedure? • Are there long-term consequences to these decisions? • What do patients need to know first to avoid any safety or health issues? There’s a lot to know about this topic, and if you are a journalist looking to learn more, then let us help with your coverage. Dr. Maria Helena Lima is one of the nation’s leading plastic surgeons with 12 years of experience specializing in aesthetic plastic surgery, facial reconstruction and craniofacial pediatric plastic surgery. She is available to speak with media about this emerging trend. Simply click on her name now to arrange an interview today.
This year marks 100 years since the signing of the Anglo-Irish Treaty, which eventually would establish Ireland as a republic, and Georgia Southern University undergraduate student Caitlyn Hudson is getting a first-hand look at some historical documents that chronicle U.S. efforts to help establish Ireland’s freedom from British rule. Hudson is researching a collection of documents called the Lawless papers, which follow Virginia-native and Irish descendant Joseph Thomas Lawless’ involvement in the southern leg of an extensive U.S. tour by Éamon de Valera, a prominent political leader in Ireland’s history. “My favorite part of working on the project has to be the physical work with the documents,” Hudson said. “It is fascinating to see primary documents in hand rather than online. It provides a unique form of analysis.” The collection, which was gifted in Fall 2020 to the Center for Irish Research and Teaching (CIRT) at Georgia Southern, includes letters, advertisements and more that document an important narrative in modern Irish-American history, according to Howard Keeley, Ph.D., director of CIRT. “These documents shed significant new light on how Ireland perceived Savannah and our region at a critical time in Irish history: that nation’s War of Independence from 1919 to 1921,” Keeley said. “The collection helps us understand the network that Éamonn de Valera and other future leaders of an independent Ireland sought to build in the American South, using as one anchor the sizable and active Irish-American community in Savannah.” All of the Lawless papers were either written or received by Lawless, the son of immigrants from County Galway, Ireland. Lawless was involved in arranging southern stops on de Valera’s tour, which included a stop at the Chatham Artillery Armory in April 1920, in an effort to raise funds for the self-proclaimed Republic of Ireland. Lawless, who would go on to become a lawyer and prominent political figure in Virginia, was also very devoted to Ireland and involved in several prominent Irish-American organizations, including the Friends of Irish Freedom (FOIF), which advocated for political independence for Ireland. “De Valera’s fundraising tour of the U.S. is among the most important episodes in modern Irish-American history,” said Keeley. “The collection sheds significant light on how FOIF used the tour to advance a southern strategy. Clearly, Judge Lawless was key to those efforts.” Keeley also pointed out that in time, de Valera would become prime minister, and then president, of an independent Ireland, dominating the country’s politics for decades. The collection was gifted to CIRT by direct descendants of Lawless and is now housed in the special collections section of the Zach S. Henderson Library. “We are honored to be granted stewardship of these documents,” said Autumn Johnson, special collections librarian at Zach S. Henderson Library. “Having increased opportunities for Georgia Southern students to examine rare, one-of-a-kind collections, such as the Lawless papers, enriches the learning experience, particularly for our undergraduates.” Hudson said her work on the project has allowed her to fully understand the various aspects of potential careers she can pursue, as well as narrow down specific goals for her graduate school journey and beyond. “This type of work is generally done by graduate students, and it is amazing to know that I am able to gain experience in a field while an undergraduate,” said Hudson. “It has allowed me to learn career-relevant material earlier on and in turn has allowed me to better prepare for graduate school and my overall future goals.” Keeley added a collection like the Lawless papers allows students and faculty to conduct research on high-value primary source documents. The collection will also help further CIRT’s ongoing mission to increase research productivity, particularly with respect to the history of the Irish in Savannah and the state of Georgia. “The Irish experience in the south is open to much more study than has thus far been attempted,” Keeley said. “The generous gift of the Lawless papers to the Center for Irish Research and Teaching significantly enhances our drive to conduct meaningful research. For undergraduate students, such as Caitlyn, the opportunity to uncover knowledge by analyzing primary-source documents brings new levels of rigor and satisfaction to the college experience. And for our program, this collaboration with the Special Collections unit of University Libraries is a powerful way to honor our donors’ trust in us and, in addition, celebrate Irish heritage, especially around St. Patrick’s Day.” If you're a journalist looking to learn more about his project of the historical significance the Irish had on Georgia - then let us help. Dr. Howard Keeley is available for interviews — simply reach out to Georgia Southern Director of Communications Jennifer Wise at jwise@georgiasouthern.edu to set and time and date.
Find out how GSU is fighting fast fashion and promoting sustainability with students on campus
Sustainability Programs at Georgia Southern University recently teamed up with student organization Fashion Menagerie, a group of fashion merchandising and apparel design students, to fight fast fashion by hosting the first campus thrift store on the Statesboro Campus. Fast fashion is a textile trend where clothes are mass-produced to be quickly sold and thrown away. “Tons of textile waste gets dumped from people throwing away their clothes, even the ones that are lightly used, but more clothing is constantly being produced,” said Geneisa Ragin, president of Fashion Menagerie. “This thrift store can help our campus prevent that increase of waste and give students a sustainable way to donate and shop that can discourage fast fashion production.” Cami Sockow, Sustainability Programs coordinator, said in addition to being wasteful, fast fashion is often characterized by poor work conditions, such as underpayment, child labor, physical and verbal abuse, and working long hours. “The social costs of fast fashion are immensely under discussed,” Sockow said. “We largely leave out the social conversation when we discuss sustainability, but this is a great example of how many social costs ensue with our addiction to consumption. So while we pay a low economic cost, we need to start asking ourselves if it is worth the social and environmental ones.” Clothing donors received shopping credits at the thrift store for each item they donate. The thrift store also gave shopping credits for donations of nonperishable food items, hygiene products and cleaning supplies to the Eagle Essentials Food Pantry. On campus programs like this provide perspective and lived experiences from students and faculty – and if you are a journalist looking to know more about Georgia Southern’s Sustainability Programs – then let us help. Cami Sockow and Geneisa Ragin are available for interviews — simply reach out to Georgia Southern Director of Communications Jennifer Wise at jwise@georgiasouthern.edu to set and time and date.
Are big changes coming to financial accountability in Ontario as Laurentian loses its elite status?
As the higher education community anxiously awaits more news on just exactly how Laurentian University in Sudbury has essentially gone bankrupt, those who oversee universities and colleges in Ontario are also watching with interest. The chain of events that led to Laurentian having to file for creditor protection reveal a failure in governance. And it points to a wider set of reforms that are being contemplated within the public sector. A special investigator’s report on the Laurentian University insolvency is coming out soon, according to the Minister of Training, Colleges and Universities, Ross Romano. The province has warned it may introduce legislation granting it greater oversight of every university’s finances. Recently, Umar Saeed, a public sector accounting expert and a partner at Welch LLP, sat down with Newspoint360 to discuss in an in-depth interview how Ontario’s ability to control and govern the university sector is unlike other provinces, such as British Columbia. If new legislation is introduced that enhances the government’s ability to appoint Board members or control the financial and operating policies of Ontario universities, it will have broad implications for the entire university sector in Ontario: • New legislation may lead to consolidating all the universities (debts and deficits) into the Ontario government’s public accounts • Legislation would acknowledge an implicit promise by the Ontario government to backstop public sector debt (including the university sector) • Public universities may lose their perceived independence if they are “controlled” for accounting purposes The story of Laurentian University is fundamentally about poor governance. However, missing from this story is the backdrop and conditions that led to poor governance. There’s a lot at stake for Laurentian, it’s faculty and staff and the provincial university sector as a whole, and if you are a journalist looking to cover this topic, then let us help. Umar Saeed is a partner at Welch LLP in Ottawa and an expert in Public-Sector Accounting Standards. Umar is available to speak with media about this subject – simply click on his icon now to arrange an email today.
Solar geoengineering - it’s a topic that has caused an ethical lightening storm in the science community. The concept is complex. Should the world take on the crisis of climate change by attempting to artificially attempting to cool the earth? It’s an idea that has the National Academies of Sciences, Engineering and Medicine seeking a billion dollars in the next five years to investigate the theory. It’s a topic that is somewhat controversial, and journalists are looking to leading experts from across America for expert insight, opinion and perspective. Prakash Kashwan, a political scientist at the University of Connecticut, said he felt the report could have better emphasized the seriousness of some concerns over others. Uncertainties about the impacts of solar geoengineering on global weather patterns have the potential to affect some regions of the world more severely than others, he pointed out. Some experts have raised concerns about potential effects of geoengineering on monsoon rainfall in parts of Asia and Africa, he said. More than 2 billion people around the world rely on these rainfall patterns to support their water and agricultural needs. These kinds of issues should be given special weight, Kashwan suggested. "Some uncertainties are much more highly consequential for the global society, and especially for the poor and vulnerable," he told E&E News. Kashwan also reiterated concerns about potential political effects. While the report makes clear that geoengineering is not a substitute for climate mitigation, he suggests that this doesn't necessarily prevent policymakers from using it in that way. "The problem is the extent to which researchers are really helpless in deciding how research is used in the political system," he said. "That part has yet to be fully appreciated." Kashwan suggests that more dialogue might be warranted before funding a national research program, with greater input from both the international community and political experts who can weigh in on the ways that geoengineering research might affect political decisions. March 26, Scientific American It's a captivating idea – but it could have political, social and ethical consequences. Dr. Kashwan has also been interviewed by The New York Times. If you are a journalist looking to learn more about solar geoengineering, its possibilities and the reasons some scientists are worried – then let us help with your coverage. Prakash Kashwan is an Associate Professor of Political Science at UConn and an expert in the areas of environmental and climate justice, planetary justice, global commons, climate governance, and climate geoengineering governance. Dr. Kashwan is available to speak with media regarding this topic – simply click on his icon now to arrange an interview today.
Kids in School: 3 Feet Apart or 6 Feet?
The Centers for Disease Control and Prevention (CDC) recently published updated guidelines for elementary schools, "now [recommending] that, with universal masking, students should maintain a distance of at least 3 feet in classroom settings" as opposed to the previous recommendation of 6 feet. While many have had strong reactions for and against this updated guidance, immunologist Joseph Comber, PhD, an associate teaching professor of biology at Villanova University, wants to add nuance to the conversation. On the one hand, Dr. Comber notes, when the CDC updates health and safety guidelines, the public can trust that as more information and data become available, the science behind the updates becomes more accurate. He stresses that studies "showed no difference in transmission between kids kept 3 feet apart or 6 feet apart in schools." Plus, Comber says, "we already know that kids younger than 10 and 11 are less likely to spread the virus than older kids and adults." However, Dr. Comber cautions that the subjects of the study followed "strict mask guidance and adherence to masking. We don't know what happens if schools enforce 3 feet of distance but are not strict with masking." He also points out that where the study was done can have an impact on the results. Comber emphasizes that "community spread is most important to the specific community and, as we've seen so far, different states and regions can spike with infections at different times." He wonders "if this is especially true in areas that have higher virus circulation than others." Dr. Comber notes that these guidelines are for elementary schools only, with one rather large caveat: "children are increasingly being infected." Another concern with these shifting regulations is whether they will impact public trust. Villanova professor Jie Xu, PhD, is an expert on science and health communications. Her concern about this change is minimal "because science is evolving." She emphasizes that "we need to be able to revise conclusions when new evidence comes in," and she sees the country's "highly politicized environment" as something to be taken more seriously, when it comes to public health. Dr. Xu cites "rising distrust in authorities and institutions (which has been going on for quite some time)" and notes that, when it comes to the nation’s children, in-person versus virtual schooling is a "highly charged issue." In the end, according to Dr. Comber, "it remains to be seen what happens when kids are packed 3 feet into classrooms on a broad scale."
Election integrity and the Peach State - What does the new voting law in Georgia mean for voters?
It’s a law that passed in record time. Georgia politics is once again capturing the national spotlight and headlines with The Election Integrity Act of 2021. Here’s what it means in a nutshell: “The new law imposes new voter identification requirements for absentee ballots, empowers state officials to take over local elections boards, limits the use of ballot drop boxes and makes it a crime to approach voters in line to give them food and water. "It's like the Christmas tree of goodies for voter suppression," Democratic state Sen. Jen Jordan said on the Senate floor as lawmakers prepared to vote on the nearly 100-page bill Thursday. Republicans cast the measure, dubbed The Election Integrity Act of 2021, as necessary to boost confidence in elections after the 2020 election saw Trump make repeated, unsubstantiated claims of fraud. By Thursday evening, a lawsuit challenging the new law had already been filed by a trio of voting rights groups: the New Georgia Project, the Black Voters Matter Fund and Rise Inc. "In large part because of the racial disparities in areas outside of voting -- such as socioeconomic status, housing, and employment opportunities -- the Voter Suppression Bill disproportionately impacts Black voters, and interacts with these vestiges of discrimination in Georgia to deny Black voters (an) equal opportunity to participate in the political process and/or elect a candidate of their choice," the lawsuit states. March 26 – CNN The new law is under a lot of scrutiny and is getting a lot of coverage. If you are a journalist looking for expert perspective on the legality and legitimacy of new law, what it may mean for future elections in Georgia voters and potentially voters across America, then let us help. Dr. Stephen Farnsworth is a sought-after political commentator on presidential politics. He has been widely featured in national media, including The Washington Post, Reuters, The Chicago Tribune and MSNBC. Dr. Farnsworth is available to speak with media any time regarding the election and its aftermath – simply click on his icon to arrange an interview today.
What Can A Forgotten Piece of Our Opioid Addiction and Treatment History Teach Us?
As the nation struggles with the third wave of a continuing opioid epidemic, a newly republished book co-authored by Nancy Campbell, the head of the Department of Science and Technology Studies at Rensselaer Polytechnic Institute, offers insight into present-day drug addiction and treatment by exploring a complex chapter from the nation’s past. Written with JP Olsen and Luke Walden, The Narcotic Farm: The Rise and Fall of America’s First Prison for Drug Addicts details the history of the United States Narcotic Farm, a federal institution that opened in 1935 outside of Lexington, Kentucky. Jointly operated from 1935 to 1975 by the U.S. Public Health Service and the Federal Bureau of Prisons, the Narcotic Farm was a combination prison, hospital, working farm, rehabilitation center, and research laboratory. “All of our scientific knowledge about human opioid addiction comes from that time, comes from that place,” said Campbell, a leading figure in the social history of drugs, drug policy, and harm reduction, on an episode of the Landmark Recovery Radio podcast. The facility, which was also the subject of a 2009 documentary featuring Campbell, has a complicated legacy. It revolutionized treatment methods commonly accepted today, such as using methadone to medically manage heroin detox and the development of drugs like naloxone and buprenorphine. But it fell under a cloud of suspicion in 1975, when Congress learned that researchers had recruited patients as test subjects for CIA-funded LSD experiments as part of the notorious MK-Ultra project. “With the ongoing opioid epidemic worsening this past year in the midst of the COVID-19 pandemic, the lessons learned in this book continue to be relevant today,” Campbell said. Campbell is also the author of Using Women: Gender, Drug Policy, and Social Justice and Discovering Addiction: The Science and Politics of Substance Abuse Research, as well as the co-author of Gendering Addiction: The Politics of Drug Treatment in a Neurochemical World. Her most recent book, OD: Naloxone and the Politics of Overdose, was published in 2020. “Nobody should die of overdose. A high overdose death rate signals that we have not cared for the people who have been hurt most by the war on drugs, first pursued by President Dwight D. Eisenhower in 1954,” Campbell said in a recent “Academic Minute” segment. Campbell is available to discuss a wide range of topics relating to drug policy and history, including the Narcotic Farm.
