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UConn Researcher Develops Successful Zika Virus Vaccine in Preclinical Studies
UConn researcher Paulo Verardi, associate professor of pathobiology and veterinary science in the College of Agriculture, Health and Natural Resources, has demonstrated the success of a vaccine against Zika virus and recently published his findings in Scientific Reports, a Nature Research publication. He has also filed provisional patents with UConn’s Technology Commercialization Services for the novel vaccine platform technology used to generate the vaccine, as well as genetic modifications made to the vaccine that significantly enhance expression of the vaccine antigen. Verardi, a Brazilian native, was in Brazil visiting family in the summer of 2015 when the Zika outbreak first began to make waves and soon reached epidemic status. Back in the United States, Verardi kept tabs on the Zika epidemic and its emerging connection to microcephaly, a serious birth defect that causes babies to be born with small heads and underdeveloped brains. In October of that year, Verardi called then-Ph.D.-student Brittany Jasperse (CAHNR ‘19) into his office and told her he wanted to apply their newly developed vaccine platform and start developing a vaccine for Zika virus. It’s an impressive achievement and there’s a full article attached for those looking to know more. Verardi emphasizes that developing vaccines for viruses, in this case Zika, help the world be better prepared for outbreaks of novel and emerging viruses by having vaccine development frameworks in place. “Emerging viruses are not going to stop popping up any time soon, so we need to be prepared,” Verardi says. “Part of being prepared is to continue the development of these platforms.” If you’re a journalist looking to know more about Zika virus and this emerging news about a vaccine – then let us help. Dr. Paulo Verardi is a virologist who specializes in vaccine research and development. He is an Associate Professor at UConn and a member of the Center of Excellence for Vaccine Research. Dr. Verardi is available to speak with media regarding this emerging development – simply click on his icon now to arrange an interview today.

As President Biden Lays Out Infrastructure Plan, Experts Available to Discuss Proposals
As President Joe Biden lays out his plan for improving the nation's infrastructure, experts from Rensselaer Polytechnic Institute are available to discuss the ways in which proposed projects could affect shipping and delivery of goods, congestion in cities, and emissions in the environment, among other topics. José Holguín-Veras, the director of the Center for Infrastructure, Transportation, and the Environment at Rensselaer, and Cara Wang, an associate professor of civil and environmental engineering at Rensselaer, are leading experts in the role of infrastructure on freight and transportation systems, and the environmental impacts of both. Their research focuses on improving transportation and freight systems in order to increase efficiency, reduce traffic congestion and, in turn, reduce vehicle emissions. Holguín-Veras and Wang can also discuss what their research has uncovered that could guide policy makers as new projects are planned.

Solar geoengineering - it’s a topic that has caused an ethical lightening storm in the science community. The concept is complex. Should the world take on the crisis of climate change by attempting to artificially attempting to cool the earth? It’s an idea that has the National Academies of Sciences, Engineering and Medicine seeking a billion dollars in the next five years to investigate the theory. It’s a topic that is somewhat controversial, and journalists are looking to leading experts from across America for expert insight, opinion and perspective. Prakash Kashwan, a political scientist at the University of Connecticut, said he felt the report could have better emphasized the seriousness of some concerns over others. Uncertainties about the impacts of solar geoengineering on global weather patterns have the potential to affect some regions of the world more severely than others, he pointed out. Some experts have raised concerns about potential effects of geoengineering on monsoon rainfall in parts of Asia and Africa, he said. More than 2 billion people around the world rely on these rainfall patterns to support their water and agricultural needs. These kinds of issues should be given special weight, Kashwan suggested. "Some uncertainties are much more highly consequential for the global society, and especially for the poor and vulnerable," he told E&E News. Kashwan also reiterated concerns about potential political effects. While the report makes clear that geoengineering is not a substitute for climate mitigation, he suggests that this doesn't necessarily prevent policymakers from using it in that way. "The problem is the extent to which researchers are really helpless in deciding how research is used in the political system," he said. "That part has yet to be fully appreciated." Kashwan suggests that more dialogue might be warranted before funding a national research program, with greater input from both the international community and political experts who can weigh in on the ways that geoengineering research might affect political decisions. March 26, Scientific American It's a captivating idea – but it could have political, social and ethical consequences. Dr. Kashwan has also been interviewed by The New York Times. If you are a journalist looking to learn more about solar geoengineering, its possibilities and the reasons some scientists are worried – then let us help with your coverage. Prakash Kashwan is an Associate Professor of Political Science at UConn and an expert in the areas of environmental and climate justice, planetary justice, global commons, climate governance, and climate geoengineering governance. Dr. Kashwan is available to speak with media regarding this topic – simply click on his icon now to arrange an interview today.

The aftermath of a mass shooting in America
Last week America was shocked by two major mass shooting events in a week. Almost 20 people were killed and so many more will suffer the short- and long-term effects of these tragic and violent events. According to recent media reports, though the election and a full year of COVID-19 dominated news coverage, 2020 was one of the deadliest years for gun violence in decades. Until two lethal rampages this month, mass shootings had largely been absent from headlines during the coronavirus pandemic. But people were still dying — at a record rate. In 2020, gun violence killed nearly 20,000 Americans, according to data from the Gun Violence Archive, more than any other year in at least two decades. An additional 24,000 people died by suicide with a gun. The vast majority of these tragedies happen far from the glare of the national spotlight, unfolding instead in homes or on city streets and — like the Covid-19 crisis — disproportionately affecting communities of color. March 23, Washington Post And as America carries on and moves forward, the survivors, witnesses and families of those killed will be adapting to a new life and a multitude of physical and psychological challenges. If you’re a reporter looking to cover the issues survivors of mass-shooting events will experience, then let us help. Dr. Laura C. Wilson is a clinical psychologist whose expertise focuses on post-trauma functioning, particularly in survivors of sexual violence or mass trauma (e.g., terrorism, mass shootings, combat). Her research interests extend to predictors of violence and aggression, including psychophysiological and personality factors, as well as indicators of PTSD following mass trauma, long-term functioning among first responders, outcomes among survivors of sexual violence, and the influence of media on mental illness stigma. Dr. Wilson is available to speak with media – simply click on her icon to arrange an interview today.

What Can A Forgotten Piece of Our Opioid Addiction and Treatment History Teach Us?
As the nation struggles with the third wave of a continuing opioid epidemic, a newly republished book co-authored by Nancy Campbell, the head of the Department of Science and Technology Studies at Rensselaer Polytechnic Institute, offers insight into present-day drug addiction and treatment by exploring a complex chapter from the nation’s past. Written with JP Olsen and Luke Walden, The Narcotic Farm: The Rise and Fall of America’s First Prison for Drug Addicts details the history of the United States Narcotic Farm, a federal institution that opened in 1935 outside of Lexington, Kentucky. Jointly operated from 1935 to 1975 by the U.S. Public Health Service and the Federal Bureau of Prisons, the Narcotic Farm was a combination prison, hospital, working farm, rehabilitation center, and research laboratory. “All of our scientific knowledge about human opioid addiction comes from that time, comes from that place,” said Campbell, a leading figure in the social history of drugs, drug policy, and harm reduction, on an episode of the Landmark Recovery Radio podcast. The facility, which was also the subject of a 2009 documentary featuring Campbell, has a complicated legacy. It revolutionized treatment methods commonly accepted today, such as using methadone to medically manage heroin detox and the development of drugs like naloxone and buprenorphine. But it fell under a cloud of suspicion in 1975, when Congress learned that researchers had recruited patients as test subjects for CIA-funded LSD experiments as part of the notorious MK-Ultra project. “With the ongoing opioid epidemic worsening this past year in the midst of the COVID-19 pandemic, the lessons learned in this book continue to be relevant today,” Campbell said. Campbell is also the author of Using Women: Gender, Drug Policy, and Social Justice and Discovering Addiction: The Science and Politics of Substance Abuse Research, as well as the co-author of Gendering Addiction: The Politics of Drug Treatment in a Neurochemical World. Her most recent book, OD: Naloxone and the Politics of Overdose, was published in 2020. “Nobody should die of overdose. A high overdose death rate signals that we have not cared for the people who have been hurt most by the war on drugs, first pursued by President Dwight D. Eisenhower in 1954,” Campbell said in a recent “Academic Minute” segment. Campbell is available to discuss a wide range of topics relating to drug policy and history, including the Narcotic Farm.

Childhood psychology expert on migrant children at U.S.-Mexico border
Kathryn Humphreys, assistant professor, department of psychology and human development, is available for commentary on the influx of migrant children at the border and group-based housing for these children. Kathryn received her doctoral degree in clinical psychology and has expertise in infant and early childhood mental health. Her research focuses on characterizing the early environment and examining links to later life outcomes. Some of her recent research finds that stressful or traumatic experiences occurring in a child’s earliest years—birth to age 5—have been linked to reduced hippocampal volume in adolescence, which is connected to learning, memory and mood.

Product Returns Represent Billion-Dollar Strategic Blind Spot for Major Retailers
“Product returns have never, to our knowledge, been explicitly included as a stage in a major customer journey model,” the authors note in their paper. “This exclusion represents a strategic blind-spot for marketers.” In December 2020, Linne Fulcher, vice president, customer strategy, science and journeys at Walmart U.S., published a blog post that outlined Walmart’s new return policy. Dubbed “Carrier Pickup by FedEx,” the service was just in time for the holidays, free, and “here to stay,” Fulcher wrote. She described the policy as “an incredibly convenient way to make that unwanted gift ‘magically’ disappear,” whether customers bought items in a store, online, or from a third party vendor. “We want the returns experience to be easy, safe and seamless,” she added. Returns are big business. According to the National Retail Federation (NRF), U.S. consumers returned an estimated $428 billion worth of merchandise last year—approximately 10.6 percent of total U.S. retail sales. The numbers for ecommerce are even more startling: online shopping accounted for roughly $565 billion of 2020 retail sales, of which $102 billion in merchandise—about 18 percent—was returned. However, retail advisory firm Optoro noted in 2019 that of 117 top retailers, not even a third of them quantify the full cost of returns. Even before the pandemic hit, Sandy Jap, Sarah Beth Brown professor in marketing, Ryan Hamilton, associate professor of marketing, and former Goizueta Business School dean, Tom Robertson, were perplexed at how little academic research existed regarding returns. “Instead of viewing returns as a nuisance and an added cost, they are an opportunity to engage with customers and build brand loyalty,” explains Robertson. “Returns are part and parcel of the new retail landscape. This has been exacerbated by the strong uptick in online.” To help retailers identify opportunities, Jap, Hamilton, and Robertson wrote “Many (Un)happy Returns? The Changing Nature of Retail Product Returns and Future Research Directions,” published in Journal of Retailing last year. The article is essentially a researcher’s road map for exploring this “strategically important area,” says Jap. Some retailers, such as Warby Parker and Stitch Fix, have built returns into their business models. Others, like Zappos and Nordstrom, have made consumer-generated returns easy, assuming that doing so engenders brand loyalty and repeat business. Yet most retailers seem “to lack a coherent philosophy” on returns and “appear not to have built return rates into their business models at all,” the trio state in their paper. “There are so many interesting and important questions to be answered around product returns,” says Hamilton. “Important as returns are, the academic marketing research has barely scratched the surface.” “Many (Un)happy Returns” highlights five specific areas where advancements in theory and practice would provide opportunity for greater understanding: 1. How product returns transform the customer journey 2. The “dark side” of returns—exploring the gray area between justified returns and outright fraud 3. The effects of returns on traditional retailer supply chains 4. Customer response to easy product returns and practices 5. The effect of retailers’ product return practices on their reputation “These questions represent a range of important directions for assembling a body of work on retailer-initiated and customer-initiated return behaviors and processes,” they write. “Ultimately, these might serve to improve the performance of return forecasting models, illuminate optimal go-to-market strategies and distribution processes in the evolving, technology-oriented marketplace that characterizes retailing today.” Each of the five points above are detailed in a piece recently published by Emory University. That article is attached here: If you are a journalist looking to cover this topic or if you are simply interested in learning more, then let us help. Ryan Hamilton, associate professor of marketing at Emory’s Goizueta Business School. Sandy Jap holds the Sarah Beth Brown Endowed Professorship of Marketing Chair at Emory’s Goizueta Business School. Both are available to speak with media, simply click on eithr expert's icon now – to book an interview today.
How well do you know your sense of touch? UMW’s Sushma Subramanian explains it all in new book
The University of Mary Washington’s Sushma Subramanian’s latest book, How to Feel: The Science and Meaning of Touch, is now available on bookstore shelves and online retailers across America. The journalist, assistant professor and author was recently featured in Discover Magazine, where she shares her inspiration for the book and sits down to answer to serious questions about science and the need to touch. Several years ago, Sushma Subramanian was procrastinating on her work when she noticed her desk was a bit wobbly. It was a rather mundane moment, she recalls, and one that’s only a vague memory now. But as she began to fiddle with the shaky tabletop, the science journalist found herself noting how the experience felt: the grain of the wood against her fingers, the pinching of her skin and the sensation of her muscles straining to lift the desk. As Subramanian explains in her book, How to Feel: The Science and Meaning of Touch, it was a moment when she began to consider how little she knew about this multifaceted sense — “a capacity,” she writes, “that never shuts off.” The questions kept forming, eventually leading Subramanian, a professor of journalism at the University of Mary Washington, to write an article for Discover in 2015 about the development of tactile touch screens — which use haptic technology, such as vibrations in handheld devices. In her latest work, she dives deeper into that world, but also explores the limits of our sense of touch and what makes it so versatile. Discover caught up with Subramanian to talk about touch in the age of COVID-19, the future of tactile research and how we experience the sense differently across personal and cultural barriers. March 08 - Discover Magazine Her interview is also part of the attached article and is a very compelling read. If you are a journalist looking to speak with Sushma Subramanian about her latest book, then let us help. Simply click on Sushma’s icon now to arrange a time and interview.

Ask the Expert: Vaccine myths and scientific facts
Now that there are authorized and recommended COVID-19 vaccines, it is critical people receive accurate information. Peter Gulick, professor of medicine at the Michigan State University College of Osteopathic Medicine and infectious disease expert, reviews some myths about the vaccine and counters these with scientific facts. Myth: The COVID-19 vaccines were developed in a rush, so their effectiveness and safety can’t be trusted. Fact: Studies found that the Pfizer/BioNTech and Moderna are both about 95% effective compared to the influenza vaccine, which ranges from being 50% to 60% effective each year. The Johnson & Johnson vaccine is 85% effective at curbing serious or moderate illness. The most important statistic is that all three were 100% effective in stopping hospitalizations and death. As of March 9, 2021, the Centers for Disease Control and Prevention reports that 93.7 million people have been vaccinated and all safety data collected from these doses show no red flags. There have been about 5 cases of anaphylaxis, an allergic reaction, per 1 million but this is no different than allergic reactions from other vaccines. There are many reasons why the COVID-19 vaccines could be developed so quickly and here are a few: The COVID-19 vaccines from Pfizer/BioNTech and Moderna were created with a messenger RNA technology that has been in development for years, so the companies could start the vaccine development process early in the pandemic. China isolated and shared genetic information about COVID-19 promptly so scientists could start working on vaccines. The vaccine developers didn’t skip any testing steps but conducted some of the steps on an overlapping schedule to gather data faster. The Pfizer/BioNTech and Moderna vaccines were created using messenger RNA, or mRNA, which allows a faster approach than the traditional way that vaccines are made. Because COVID-19 is so contagious and widespread, it did not take long to see if the vaccine worked for the vaccinated study volunteers. Companies began making vaccines early in the process — even before FDA authorization — so some supplies were ready when authorization occurred. They develop COVID-19 vaccines so quickly also due to years of previous research on the SARS COV-1, a related virus. Myth: The messenger RNA technology used to make the Pfizer/BioNTech and Moderna COVID-19 vaccine is brand new. Fact: The messenger RNA technology behind these two vaccines has been studied and in development for almost two decades. Interest has grown in these vaccines because they can be developed in a laboratory using readily available materials, making vaccine development faster. mRNA vaccines have been studied before for flu, Zika and rabies. Myth: You only need one dose of J&J vaccine so it’s more effective. Fact: Johnson & Johnson’s vaccine uses a different strategy — a weakened cold virus that is reprogrammed to include the code for the spike protein. Once inside the body, the viral genes trigger a similar response against the virus. All three vaccines are considered overall effective and 100% effective in preventing hospitalizations and death. Myth: Vaccine efficacy and effectiveness mean the same thing. Fact: Efficacy and effectiveness do not mean the same thing. “Efficacy” refers to the results for how well a drug or vaccine works based on testing while “effectiveness” refers to how well these products work in the real world, in a much larger group of people. Most people, however, use them interchangeably even though they have different scientific meanings. Myth: The vaccines aren’t effective against new strains of the virus. Fact: Currently, we know both the U.K. strain as well as the South African variant have increased transmissibility of 30% to 50% over the natural strain. As far as an increase in causing more serious disease, it is not known yet. We have over 600 U.K. variants in Michigan and one case of the South African variant, and I just heard of 47 cases of the U.K. variant in Grand Ledge. We (Michigan) are second in the nation in variants, but that's likely because we test for them more. The most important information is that the vaccines, in general, are 100% effective in prevention of hospitalization and death. So, it is felt they all offer some protection against variants to prevent serious disease. As far as the Johnson & Johnson, it was used with variants and has efficacy overall of 72% in U.S., 66% in Latin America and 57% in South Africa (where the main strain is the South African variant). All companies are looking at modifying (their products) (the mRNA) to cover variants and either give a booster or a multivalent vaccine to cover all variants. Myth: There are severe side effects of the COVID-19 vaccines. Fact: The COVID-19 vaccine can have side effects, but the vast majority go away quickly and aren’t serious. The vaccine developers report that some people experience pain where they were injected; body aches; headaches or fever, lasting for a day or two. This is good and are signs that the vaccine is working to stimulate your immune system. If symptoms persist beyond two days, you should call your doctor. Myth: Getting the COVID-19 vaccine gives you COVID-19. Fact: The vaccine for COVID-19 cannot and will not give you COVID-19. The two authorized mRNA vaccines instruct your cells to reproduce a protein that is part of the SARS-CoV-2 coronavirus, which helps your body recognize and fight the virus, if it comes along. The COVID-19 vaccine does not contain the SARS-Co-2 virus, so you cannot get COVID-19 from the vaccine. The Johnson & Johnson vaccine was developed using adenovirus vector technology and also will not give you COVID-19. It shows your immune system a weakened, common cold virus “disguised” as the coronavirus instead. Adenovirus vaccines have been around for about two decades, the same as mRNA vaccines. Johnson & Johnson developed a vaccine for Ebola using this technology. Myth: The vaccines are ineffective against the virus variants. Fact: More time is needed to study the vaccines’ effectiveness against the variants. Studies are now being conducted to determine if a booster dose is needed to protect against the variants or if modifications to the vaccines are needed. Myth: I already had COVID-19 and I have recovered, so I don't need to get the vaccine. Fact: There is not enough information currently available to say if or for how long after getting COVID-19 someone is protected from getting it again. This is called natural immunity. Early evidence suggests natural immunity from COVID-19 may not last very long, but more studies are needed to better understand this. The CDC recommends getting the COVID-19 vaccine, even if you’ve had COVID-19 previously. However, those that had COVID-19 should delay getting the vaccination until about 90 days from diagnosis. People should not get vaccinated if in quarantine after exposure or if they have COVID-19 symptoms. Myth: I won't need to wear a mask after I get the vaccine. Fact: It may take time for everyone who wants a COVID-19 vaccination to get one. Also, while the vaccine may prevent you from getting sick, more research is needed, but early indications show that while the vaccine is effective in reducing transmission, it is possible for a vaccinated person to spread the virus. Until more is understood about how well the vaccine works, continuing with precautions such as mask-wearing and physical distancing will be important. Myth: COVID-19 vaccines will alter my DNA. Fact: The COVID-19 vaccines will not alter any human genome and cannot make any changes to your DNA. The vaccines contain all the instructions necessary to teach your cells to make SARS-CoV-2's signature spike protein, release it out into the body, and your immune system gets a practice round at fighting off COVID-19. Myth: The COVID-19 vaccine can affect women’s fertility Fact: There is currently no evidence that antibodies formed from COVID-19 vaccination cause any problems with pregnancy, including the development of the placenta. In addition, there is no evidence suggesting that fertility problems are a side effect of any vaccine. People who are trying to become pregnant now or who plan to try in the future may receive the COVID-19 vaccine when it becomes available to them but it’s always prudent to consult with your doctor. Myth: The COVID-19 vaccine was developed to control the general population either through microchip tracking or "nanotransducers" in our brains. Fact: There is no vaccine microchip, and the vaccine cannot track people or gather personal information into a database. Myth: The vaccines were developed and produced using fetal tissue. Fact: The vaccines do not contain fetal cells nor were fetal cells used in the production the Pfizer and Moderna vaccines. Johnson & Johnson used human cell lines or also known as cell cultures to grow the harmless adenovirus but did not use fetal tissue. These same cell lines have been used for other vaccines including hepatitis, chickenpox and rabies and have been around for years. Peter Gulick is an associate professor of medicine at Michigan State University, College of Osteopathic Medicine, and serves as adjunct faculty in the College of Human Medicine and the College of Nursing. Dr. Gulick is available to speak with media - simply click on his icon now to arrange an interview today. Peter Gulick is an associate professor of medicine at Michigan State University, College of Osteopathic Medicine, and serves as adjunct faculty in the College of Human Medicine and the College of Nursing. Dr. Gulick is available to speak with media - simply click on his icon now to arrange an interview today.

Immigration history expert can provide insight on anti-Asian racism in the U.S.
Anti-Asian hate crimes are on the rise in America, and new data has revealed over the past year that the number of these incidents — which can include shunning, verbal harassment and physical attacks — is greater than previously reported. And a disproportionate number have been directed at Asian women, such as the recent Atlanta spa shootings and the assault on an elderly woman in San Francisco. The research released by reporting forum Stop AAPI Hate on Tuesday revealed nearly 3,800 incidents were reported over the course of roughly a year during the pandemic. It’s a significantly higher number than last year's count of about 2,800 hate incidents nationwide over the span of five months. Women made up a far higher share of the reports, at 68 percent, compared to men, who made up 29 percent of respondents. The non-profit does not report incidents to police. The data, which includes incidents that occurred between March 19 of last year and Feb. 28 of this year, shows that roughly 503 incidents took place in 2021 alone. Verbal harassment and shunning were the most common types of discrimination, making up 68.1 percent and 20.5 percent of the reports respectively. The third most common category, physical assault, made up 11.1 percent of the total incidents. More than a third of incidents occurred at businesses, the primary site of discrimination, while a quarter took place in public streets. According to the data, Asian women report hate incidents 2.3 times more than men. A further examination of the submitted reports showed that in many cases, the verbal harassment that women received reflected the very intersection of racism and sexism. March 16 – NBC News If you’re a journalist covering this news story, then let us help. Dr. Krystyn Moon is an expert in U.S. immigration history, popular culture, race and ethnic studies – and is available to speak with media regarding the recent study and the history of the anti-Asian racism and violence in the United States. If you are looking to arrange an interview, simply click on her icon now to book a time today.






